MPD: Project measures / variables set: Schonfeld1 AUC

Project measures / variables set: Schonfeld1 AUC_ITT

ID, description, units	MPD:32318 AUC_ITT glucose levels, area under curve, insulin tolerance test (human insulin 0.75 U/kg bw i.p., 5h fast) [AUC]
Measures	• 0 to 60 min • 0 to 120 min
Data set, strains	Schonfeld1 inbred 10 strains sex: both age: 9-13wks
Procedure	insulin tolerance
Comparison	timecourse, same cohort
Ontology mappings	VT:0000188 blood glucose amount VT:0015088 glucose metabolism trait MA:0000059 blood MP:0005291 abnormal glucose tolerance

Values Means Δ Means Z-scores

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Schonfeld1 - glucose levels, area under curve, insulin tolerance test (human insulin 0.75 U/kg bw i.p., 5h fast)

ANOVA Summary "within" = Within error "between" = Between Error (Animal ID)

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
between sex	1	5935414.4222	5935414.4222	1.9112	0.1711
between strain	8	376303699.6111	47037962.4514	15.1464	< 0.0001
between sex:strain	8	59661843.8778	7457730.4847	2.4014	0.0235
between Residuals	72	223599552.4	3105549.3389
within group	1	1099427004.0889	1099427004.0889	1742.2071	< 0.0001
within group:sex	1	3704883.2	3704883.2	5.8709	0.0179
within group:strain	8	90476705.6111	11309588.2014	17.9217	< 0.0001
within group:sex:strain	8	14109214.5	1763651.8125	2.7948	0.0094
within Residuals	72	45435897.6	631054.1333

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Schonfeld1	32318	insulin tolerance	(none)	glucose levels, area under curve, insulin tolerance test (human insulin 0.75 U/kg bw i.p., 5h fast) [AUC] 0 to 60 min AUC_ITT1	inbred	10	both	9-13wks
Schonfeld1	32319	insulin tolerance	(none)	glucose levels, area under curve, insulin tolerance test (human insulin 0.75 U/kg bw i.p., 5h fast) [AUC] 0 to 120 min AUC_ITT2	inbred	10	both	9-13wks