MPD: Project measures / variables set: Jaxpheno3 T4

Project measures / variables set: Jaxpheno3 T4

ID, description, units	MPD:22820 T4 thyroxine (plasma T4) [µg/dL]
Measures	• age 8wks • age 16wks
Data set, strains	Jaxpheno3 inbred 11 strains sex: both
Procedure	metabolic panel
Comparison	multiple cohorts measured at two age timepoints
Ontology mappings	VT:0005475 blood thyroxine amount MA:0002501 plasma MP:0005475 abnormal circulating thyroxine level

Values Means Δ Means Z-scores

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Jaxpheno3 - thyroxine (plasma T4)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
age	1	7.1667	7.1667	7.192	0.0075
age:sex	1	0.3371	0.3371	0.3383	0.561
age:sex:strain	7	78.2019	11.1717	11.2111	< 0.0001
age:strain	7	87.4998	12.5	12.544	< 0.0001
Residuals	541	539.1006	0.9965
sex	1	11.933	11.933	11.9751	0.0006
sex:strain	7	146.794	20.9706	21.0445	< 0.0001
strain	7	479.6918	68.5274	68.7689	< 0.0001

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Jaxpheno3	22820	metabolic panel	(none)	thyroxine (plasma T4) [µg/dL] at age 8wks T4_8	inbred	11	both	8wks
Jaxpheno3	22821	metabolic panel	(none)	thyroxine (plasma T4) [µg/dL] at age 16wks T4_16	inbred	8	both	16wks