MPD: Project measures / variables set: Graubert1 adenoma

Project measures / variables set: Graubert1 adenoma_lung

ID, description, units	MPD:11616 adenoma_lung lung adenoma frequency rate [score] ENU study
Measures	• control • ENU
Data set, strains	Graubert1 inbred 20 strains sex: both age: 13-68wks
Procedure	histopathology
Comparison	control group vs. treated group
Ontology mappings	VT:0001175 lung morphology trait VT:0010487 response to xenobiotic stimulus trait MA:0000415 lung MP:0008872 abnormal physiological response to xenobiotic MP:0010639 altered tumor pathology MP:0013151 abnormal incidence of induced tumors

Values Means Δ Means Z-scores

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Graubert1 - lung adenoma frequency rate

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	0.2	0.2	7.4607	0.0066
group:sex	1	0.1443	0.1443	5.3833	0.0209
group:sex:strain	18	0.5984	0.0332	1.24	0.2259
group:strain	18	0.754	0.0419	1.5625	0.0669
Residuals	373	10.0	0.0268
sex	1	0.3357	0.3357	12.5228	0.0005
sex:strain	18	0.7199	0.04	1.4917	0.0893
strain	18	0.8111	0.0451	1.6809	0.0404

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Graubert1	11616	histopathology	ENU	lung adenoma frequency rate [score] control adenoma_lung	inbred	20	both	13-68wks
Graubert1	11656	histopathology	ENU	lung adenoma frequency rate [score] ENU adenoma_lung_enu	inbred	20	both	13-68wks