Project measure / variable:   Levy1   Tb_connectivity

ID, description, units MPD:54905   Tb_connectivity   trabecular bone connectivity density of femur (Conn.D)   [mm-3]  
Data set, strains Levy1   CC pre   31 strains     sex: both     age: 8-14wks
Procedure computed tomography
Ontology mappings

  STRAIN COMPARISON PLOT
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Levy1 - trabecular bone connectivity density of femur (Conn.D)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested24 strains27 strains
Mean of the strain means85.4   mm-3 118   mm-3
Median of the strain means64.9   mm-3 117   mm-3
SD of the strain means± 54.1 ± 50.2
Coefficient of variation (CV)0.634 0.424
Min–max range of strain means16.0   –   194   mm-3 9.96   –   220   mm-3
Mean sample size per strain3.0   mice 3.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 21580.7307 21580.7307 24.575 < 0.0001
strain 16 234491.6162 14655.726 16.6892 < 0.0001
sex:strain 16 54697.449 3418.5906 3.8929 < 0.0001
Residuals 88 77277.88 878.1577


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
PreCC1061/Tau f 55.1 33.9   2   24.0 0.615 31.1, 79.1 -0.56
PreCC111/Tau f 160.0 28.7   5 12.8 0.179 133.0, 208.0 1.38
PreCC111/Tau m 146.0 13.4   4 6.68 0.0918 130.0, 163.0 0.55
PreCC1156/Tau m 138.0 2.96   2   2.09 0.0214 136.0, 140.0 0.39
PreCC1379/Tau m 152.0 0.0   1   0.0 0.0 152.0, 152.0 0.67
PreCC1452/Tau m 116.0 0.0   1   0.0 0.0 116.0, 116.0 -0.05
PreCC1513/Tau f 194.0 11.9   4 5.93 0.0612 181.0, 208.0 2.01
PreCC1513/Tau m 220.0 22.2   3 12.8 0.101 195.0, 236.0 2.03
PreCC188/Tau f 58.3 35.4   2   25.1 0.608 33.2, 83.3 -0.5
PreCC188/Tau m 53.4 14.9   7 5.62 0.278 31.5, 76.4 -1.29
PreCC1912/Tau f 155.0 16.9   2   12.0 0.109 143.0, 167.0 1.29
PreCC1912/Tau m 153.0 59.2   4 29.6 0.386 96.4, 206.0 0.69
PreCC2126/Tau f 16.0 15.3   4 7.63 0.952 2.89, 36.9 -1.28
PreCC2126/Tau m 9.96 5.42   2   3.84 0.545 6.12, 13.8 -2.16
PreCC2156/Tau f 104.0 21.6   3 12.5 0.208 79.3, 118.0 0.34
PreCC2156/Tau m 104.0 51.8   5 23.2 0.5 29.9, 167.0 -0.28
PreCC2391/Tau m 17.2 18.5   2   13.1 1.08 4.04, 30.3 -2.01
PreCC2438/Tau f 187.0 0.0   1   0.0 0.0 187.0, 187.0 1.88
PreCC2573/Tau m 128.0 55.2   3 31.9 0.433 77.9, 187.0 0.19
PreCC2680/Tau f 45.4 2.19   2   1.55 0.0482 43.8, 46.9 -0.74
PreCC2680/Tau m 76.9 35.4   5 15.8 0.46 20.6, 109.0 -0.82
PreCC2689/Tau f 67.0 7.95   4 3.98 0.119 59.6, 78.3 -0.34
PreCC2689/Tau m 121.0 35.3   2   25.0 0.292 96.1, 146.0 0.05
PreCC2750/Tau f 32.9 3.72   2   2.63 0.113 30.3, 35.5 -0.97
PreCC2750/Tau m 112.0 61.4   3 35.5 0.551 59.1, 179.0 -0.12
PreCC3348/Tau f 181.0 0.0   1   0.0 0.0 181.0, 181.0 1.77
PreCC3348/Tau m 172.0 17.2   6 7.04 0.1 142.0, 194.0 1.07
PreCC3438/Tau f 45.7 26.0   2   18.4 0.568 27.3, 64.1 -0.73
PreCC3438/Tau m 102.0 49.2   3 28.4 0.483 73.4, 159.0 -0.32
PreCC3480/Tau f 17.7 23.2   2   16.4 1.31 1.31, 34.2 -1.25
PreCC3480/Tau m 142.0 0.0   1   0.0 0.0 142.0, 142.0 0.47
PreCC3912/Tau f 98.4 20.7   5 9.27 0.211 70.3, 125.0 0.24
PreCC3912/Tau m 117.0 38.9   5 17.4 0.331 88.8, 176.0 -0.03
PreCC4052/Tau f 44.2 16.0   7 6.06 0.363 24.3, 67.3 -0.76
PreCC4052/Tau m 148.0 31.8   5 14.2 0.215 115.0, 197.0 0.59
PreCC4141/Tau f 65.6 22.8   3 13.2 0.348 39.3, 80.3 -0.37
PreCC4141/Tau m 193.0 31.9   3 18.4 0.165 159.0, 222.0 1.49
PreCC4438/Tau f 61.2 9.25   3 5.34 0.151 51.3, 69.6 -0.45
PreCC4457/Tau f 99.7 9.68   4 4.84 0.0971 93.5, 114.0 0.26
PreCC4457/Tau m 150.0 56.2   3 32.5 0.375 86.2, 193.0 0.63
PreCC519/Tau f 121.0 19.2   4 9.58 0.158 101.0, 146.0 0.66
PreCC519/Tau m 73.4 20.5   2   14.5 0.279 58.9, 87.9 -0.89
PreCC521/Tau f 36.7 5.7   3 3.29 0.155 30.1, 40.2 -0.9
PreCC521/Tau m 65.1 17.9   4 8.95 0.275 49.4, 90.4 -1.06
PreCC557/Tau f 54.4 29.2   4 14.6 0.537 27.5, 94.3 -0.57
PreCC611/Tau m 93.2 12.0   3 6.93 0.129 84.1, 107.0 -0.5
PreCC670/Tau m 195.0 34.3   3 19.8 0.176 159.0, 227.0 1.53
PreCC711/Tau f 84.4 6.32   2   4.47 0.0749 79.9, 88.9 -0.02
PreCC711/Tau m 94.0 0.0   1   0.0 0.0 94.0, 94.0 -0.48
PreCC72/Tau f 64.3 16.6   3 9.56 0.258 49.6, 82.2 -0.39
PreCC72/Tau m 101.0 17.5   3 10.1 0.172 84.8, 120.0 -0.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
PreCC111/Tau f 160.2613 13.2526 186.5981 133.9245
PreCC111/Tau m 145.5587 14.8169 175.0041 116.1133
PreCC1513/Tau f 193.7857 14.8169 223.2311 164.3403
PreCC1513/Tau m 220.1801 17.109 254.1807 186.1794
PreCC188/Tau f 58.2774 20.9542 99.9195 16.6353
PreCC188/Tau m 53.4281 11.2005 75.6867 31.1695
PreCC1912/Tau f 155.2394 20.9542 196.8814 113.5973
PreCC1912/Tau m 153.4445 14.8169 182.8899 123.9991
PreCC2126/Tau f 16.0295 14.8169 45.4749 0.0
PreCC2126/Tau m 9.9586 20.9542 51.6006 0.0
PreCC2156/Tau f 104.2111 17.109 138.2117 70.2105
PreCC2156/Tau m 103.6409 13.2526 129.9776 77.3041
PreCC2680/Tau f 45.3751 20.9542 87.0172 3.733
PreCC2680/Tau m 76.8891 13.2526 103.2259 50.5523
PreCC2689/Tau f 66.9815 14.8169 96.4269 37.5361
PreCC2689/Tau m 121.1103 20.9542 162.7524 79.4683
PreCC2750/Tau f 32.9178 20.9542 74.5598 0.0
PreCC2750/Tau m 111.5435 17.109 145.5441 77.5429
PreCC3438/Tau f 45.7114 20.9542 87.3534 4.0693
PreCC3438/Tau m 101.9201 17.109 135.9207 67.9195
PreCC3912/Tau f 98.3609 13.2526 124.6976 72.0241
PreCC3912/Tau m 117.3965 13.2526 143.7333 91.0597
PreCC4052/Tau f 44.1796 11.2005 66.4382 21.921
PreCC4052/Tau m 147.8716 13.2526 174.2083 121.5348
PreCC4141/Tau f 65.5686 17.109 99.5692 31.5679
PreCC4141/Tau m 193.278 17.109 227.2786 159.2773
PreCC4457/Tau f 99.6698 14.8169 129.1152 70.2243
PreCC4457/Tau m 149.7682 17.109 183.7689 115.7676
PreCC519/Tau f 121.4303 14.8169 150.8757 91.9849
PreCC519/Tau m 73.4145 20.9542 115.0565 31.7724
PreCC521/Tau f 36.7012 17.109 70.7018 2.7006
PreCC521/Tau m 65.0745 14.8169 94.5199 35.6291
PreCC72/Tau f 64.2646 17.109 98.2652 30.264
PreCC72/Tau m 101.3657 17.109 135.3664 67.3651


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
PreCC111/Tau both 152.91 9.9395 172.6626 133.1574
PreCC1513/Tau both 206.9829 11.3166 229.4722 184.4936
PreCC188/Tau both 55.8528 11.8799 79.4616 32.2439
PreCC1912/Tau both 154.3419 12.8318 179.8424 128.8414
PreCC2126/Tau both 12.994 12.8318 38.4945 0.0
PreCC2156/Tau both 103.926 10.8207 125.4299 82.4221
PreCC2680/Tau both 61.1321 12.3967 85.7679 36.4963
PreCC2689/Tau both 94.0459 12.8318 119.5464 68.5454
PreCC2750/Tau both 72.2306 13.5259 99.1105 45.3508
PreCC3438/Tau both 73.8157 13.5259 100.6956 46.9359
PreCC3912/Tau both 107.8787 9.371 126.5016 89.2558
PreCC4052/Tau both 96.0256 8.6759 113.2671 78.7841
PreCC4141/Tau both 129.4233 12.0979 153.4653 105.3812
PreCC4457/Tau both 124.719 11.3166 147.2083 102.2297
PreCC519/Tau both 97.4224 12.8318 122.9228 71.9219
PreCC521/Tau both 50.8878 11.3166 73.3771 28.3985
PreCC72/Tau both 82.8152 12.0979 106.8572 58.7731




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA