Project measure / variable:   HMDPpheno8   SO_sphingomyelin

ID, description, units MPD:50383   SO_sphingomyelin   liver stearoyl sphingomyelin (16h fast), relative abundance    
Data set, strains HMDPpheno8   HMDP   96 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings


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  STRAIN COMPARISON PLOT
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HMDPpheno8 - liver stearoyl sphingomyelin (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested96 strains
Mean of the strain means454195   None
Median of the strain means444280   None
SD of the strain means± 134497
Coefficient of variation (CV)0.296
Min–max range of strain means161483   –   778162   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 20 665588762207.73 33279438110.3865 0.5575 0.9129
Residuals 31 1850509636091.05 59693859228.7436


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 778162.0 0.0   1   0.0 0.0 778162.0, 778162.0 2.41
A/J m 481398.0 0.0   1   0.0 0.0 481398.0, 481398.0 0.2
AKR/J m 438640.0 0.0   1   0.0 0.0 438640.0, 438640.0 -0.12
AXB13/PgnJ m 367676.0 0.0   1   0.0 0.0 367676.0, 367676.0 -0.64
AXB15/PgnJ m 396967.0 0.0   1   0.0 0.0 396967.0, 396967.0 -0.43
AXB19a/PgnJ m 565229.0 0.0   1   0.0 0.0 565229.0, 565229.0 0.83
AXB19b/PgnJ m 378769.0 117520.0   2   83099.0 0.31 295670.0, 461868.0 -0.56
AXB19/PgnJ m 416997.0 0.0   1   0.0 0.0 416997.0, 416997.0 -0.28
AXB23/PgnJ m 515842.0 0.0   1   0.0 0.0 515842.0, 515842.0 0.46
AXB24/PgnJ m 499592.0 182895.0   2   129326.0 0.366 370266.0, 628918.0 0.34
AXB2/PgnJ m 412892.0 0.0   1   0.0 0.0 412892.0, 412892.0 -0.31
AXB4/PgnJ m 525462.0 0.0   1   0.0 0.0 525462.0, 525462.0 0.53
AXB5/PgnJ m 352034.0 0.0   1   0.0 0.0 352034.0, 352034.0 -0.76
AXB6/PgnJ m 326766.0 0.0   1   0.0 0.0 326766.0, 326766.0 -0.95
AXB8/PgnJ m 239512.0 0.0   1   0.0 0.0 239512.0, 239512.0 -1.6
BALB/cJ m 729137.0 1497.0   3 865.0 0.00205 728055.0, 730846.0 2.04
BTBR T+ Itpr3tf/J m 553854.0 0.0   1   0.0 0.0 553854.0, 553854.0 0.74
BUB/BnJ m 534153.0 0.0   1   0.0 0.0 534153.0, 534153.0 0.59
BXA11/PgnJ m 439600.0 0.0   1   0.0 0.0 439600.0, 439600.0 -0.11
BXA12/PgnJ m 345759.0 0.0   1   0.0 0.0 345759.0, 345759.0 -0.81
BXA13/PgnJ m 478734.0 0.0   1   0.0 0.0 478734.0, 478734.0 0.18
BXA14/PgnJ m 242048.0 0.0   1   0.0 0.0 242048.0, 242048.0 -1.58
BXA16/PgnJ m 338255.0 7594.0   2   5370.0 0.0225 332885.0, 343625.0 -0.86
BXA24/PgnJ m 383169.0 0.0   1   0.0 0.0 383169.0, 383169.0 -0.53
BXA25/PgnJ m 375321.0 0.0   1   0.0 0.0 375321.0, 375321.0 -0.59
BXA26/PgnJ m 290496.0 0.0   1   0.0 0.0 290496.0, 290496.0 -1.22
BXA2/PgnJ m 580582.0 0.0   1   0.0 0.0 580582.0, 580582.0 0.94
BXA4/PgnJ m 312319.0 0.0   1   0.0 0.0 312319.0, 312319.0 -1.05
BXA7/PgnJ m 382961.0 0.0   1   0.0 0.0 382961.0, 382961.0 -0.53
BXA8/PgnJ m 305788.0 0.0   1   0.0 0.0 305788.0, 305788.0 -1.1
BXD11/TyJ m 161483.0 0.0   1   0.0 0.0 161483.0, 161483.0 -2.18
BXD15/TyJ m 184546.0 0.0   1   0.0 0.0 184546.0, 184546.0 -2.0
BXD18/TyJ m 379530.0 0.0   1   0.0 0.0 379530.0, 379530.0 -0.56
BXD19/TyJ m 390865.0 308218.0   2   217943.0 0.789 172922.0, 608808.0 -0.47
BXD20/TyJ m 760148.0 0.0   1   0.0 0.0 760148.0, 760148.0 2.27
BXD21/TyJ m 432424.0 0.0   1   0.0 0.0 432424.0, 432424.0 -0.16
BXD22/TyJ m 695876.0 0.0   1   0.0 0.0 695876.0, 695876.0 1.8
BXD24/TyJ m 413169.0 0.0   1   0.0 0.0 413169.0, 413169.0 -0.31
BXD24/TyJ-Cep290rd16/J m 494711.0 0.0   1   0.0 0.0 494711.0, 494711.0 0.3
BXD28/TyJ m 471754.0 39780.0   2   28128.0 0.0843 443626.0, 499882.0 0.13
BXD29-Tlr4lps-2J/J m 661724.0 0.0   1   0.0 0.0 661724.0, 661724.0 1.54
BXD2/TyJ m 300008.0 0.0   1   0.0 0.0 300008.0, 300008.0 -1.15
BXD32/TyJ m 559144.0 0.0   1   0.0 0.0 559144.0, 559144.0 0.78
BXD33/TyJ m 459641.0 0.0   1   0.0 0.0 459641.0, 459641.0 0.04
BXD34/TyJ m 404717.0 0.0   1   0.0 0.0 404717.0, 404717.0 -0.37
BXD36/TyJ m 451427.0 0.0   1   0.0 0.0 451427.0, 451427.0 -0.02
BXD38/TyJ m 463310.0 0.0   1   0.0 0.0 463310.0, 463310.0 0.07
BXD39/TyJ m 467544.0 0.0   1   0.0 0.0 467544.0, 467544.0 0.1
BXD40/TyJ m 385848.0 0.0   1   0.0 0.0 385848.0, 385848.0 -0.51
BXD42/TyJ m 442639.0 0.0   1   0.0 0.0 442639.0, 442639.0 -0.09
BXD5/TyJ m 465280.0 0.0   1   0.0 0.0 465280.0, 465280.0 0.08
BXD6/TyJ m 426115.0 0.0   1   0.0 0.0 426115.0, 426115.0 -0.21
BXD8/TyJ m 478640.0 0.0   1   0.0 0.0 478640.0, 478640.0 0.18
BXD9/TyJ m 329758.0 0.0   1   0.0 0.0 329758.0, 329758.0 -0.93
BXH20/KccJ m 713693.0 0.0   1   0.0 0.0 713693.0, 713693.0 1.93
BXH22/KccJ m 451621.0 0.0   1   0.0 0.0 451621.0, 451621.0 -0.02
BXH2/TyJ m 469944.0 0.0   1   0.0 0.0 469944.0, 469944.0 0.12
BXH4/TyJ m 365272.0 30424.0   2   21513.0 0.0833 343759.0, 386785.0 -0.66
BXH6/TyJ m 480256.0 0.0   1   0.0 0.0 480256.0, 480256.0 0.19
BXH7/TyJ m 618832.0 0.0   1   0.0 0.0 618832.0, 618832.0 1.22
BXH8/TyJ m 460139.0 0.0   1   0.0 0.0 460139.0, 460139.0 0.04
BXH9/TyJ m 493941.0 0.0   1   0.0 0.0 493941.0, 493941.0 0.3
C3H/HeJ m 425553.0 11457.0   2   8101.0 0.0269 417452.0, 433654.0 -0.21
C57BL/6J m 448417.0 65753.0   4 32877.0 0.147 404169.0, 545028.0 -0.04
C57L/J m 426855.0 0.0   1   0.0 0.0 426855.0, 426855.0 -0.2
C58/J m 637746.0 0.0   1   0.0 0.0 637746.0, 637746.0 1.36
CAST/EiJ m 406572.0 0.0   1   0.0 0.0 406572.0, 406572.0 -0.35
CBA/J m 285125.0 0.0   1   0.0 0.0 285125.0, 285125.0 -1.26
CE/J m 201197.0 0.0   1   0.0 0.0 201197.0, 201197.0 -1.88
CXB11/HiAJ m 371648.0 181045.0   2   128018.0 0.487 243630.0, 499666.0 -0.61
CXB12/HiAJ m 612521.0 100976.0   2   71401.0 0.165 541120.0, 683921.0 1.18
CXB13/HiAJ m 579089.0 189159.0   3 109211.0 0.327 460689.0, 797245.0 0.93
CXB1/ByJ m 482845.0 129456.0   3 74742.0 0.268 395943.0, 631629.0 0.21
CXB2/ByJ m 734174.0 839708.0   3 484806.0 1.14 244920.0, 1703771.0 2.08
CXB3/ByJ m 614481.0 27438.0   2   19402.0 0.0447 595080.0, 633883.0 1.19
CXB4/ByJ m 352243.0 85856.0   2   60710.0 0.244 291533.0, 412952.0 -0.76
CXB6/ByJ m 422448.0 62659.0   3 36176.0 0.148 358155.0, 483335.0 -0.24
CXB7/ByJ m 513413.0 54079.0   2   38240.0 0.105 475173.0, 551653.0 0.44
CXB8/HiAJ m 536284.0 52644.0   2   37225.0 0.0982 499058.0, 573509.0 0.61
CXB9/HiAJ m 501634.0 216903.0   3 125229.0 0.432 370001.0, 751980.0 0.35
DBA/2J m 445920.0 78613.0   4 39307.0 0.176 377464.0, 559228.0 -0.06
FVB/NJ m 734770.0 0.0   1   0.0 0.0 734770.0, 734770.0 2.09
I/LnJ m 554747.0 0.0   1   0.0 0.0 554747.0, 554747.0 0.75
KK/HlJ m 178040.0 0.0   1   0.0 0.0 178040.0, 178040.0 -2.05
LG/J m 348178.0 0.0   1   0.0 0.0 348178.0, 348178.0 -0.79
LP/J m 404731.0 0.0   1   0.0 0.0 404731.0, 404731.0 -0.37
MA/MyJ m 313757.0 0.0   1   0.0 0.0 313757.0, 313757.0 -1.04
NOD/ShiLtJ m 563490.0 0.0   1   0.0 0.0 563490.0, 563490.0 0.81
NON/ShiLtJ m 519892.0 0.0   1   0.0 0.0 519892.0, 519892.0 0.49
NZW/LacJ m 198161.0 0.0   1   0.0 0.0 198161.0, 198161.0 -1.9
PL/J m 417118.0 0.0   1   0.0 0.0 417118.0, 417118.0 -0.28
RIIIS/J m 724106.0 0.0   1   0.0 0.0 724106.0, 724106.0 2.01
SEA/GnJ m 428278.0 0.0   1   0.0 0.0 428278.0, 428278.0 -0.19
SJL/J m 355095.0 0.0   1   0.0 0.0 355095.0, 355095.0 -0.74
SM/J m 535252.0 0.0   1   0.0 0.0 535252.0, 535252.0 0.6
SWR/J m 606792.0 0.0   1   0.0 0.0 606792.0, 606792.0 1.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
AXB19b/PgnJ m 378768.9 172762.6395 731120.6263 26417.1737
AXB24/PgnJ m 499592.3 172762.6395 851944.0263 147240.5737
BALB/cJ m 729136.9333 141060.1045 1016830.9132 441442.9535
BXA16/PgnJ m 338254.9 172762.6395 690606.6263 0.0
BXD19/TyJ m 390865.1 172762.6395 743216.8263 38513.3737
BXD28/TyJ m 471754.0 172762.6395 824105.7263 119402.2737
BXH4/TyJ m 365271.8 172762.6395 717623.5263 12920.0737
C3H/HeJ m 425552.9 172762.6395 777904.6263 73201.1737
C57BL/6J m 448416.575 122161.6339 697566.8701 199266.2799
CXB11/HiAJ m 371648.15 172762.6395 723999.8763 19296.4237
CXB12/HiAJ m 612520.55 172762.6395 964872.2763 260168.8237
CXB13/HiAJ m 579089.2667 141060.1045 866783.2465 291395.2868
CXB1/ByJ m 482844.8 141060.1045 770538.7798 195150.8202
CXB2/ByJ m 734173.9 141060.1045 1021867.8798 446479.9202
CXB3/ByJ m 614481.2 172762.6395 966832.9263 262129.4737
CXB4/ByJ m 352242.65 172762.6395 704594.3763 0.0
CXB6/ByJ m 422447.5333 141060.1045 710141.5132 134753.5535
CXB7/ByJ m 513413.0 172762.6395 865764.7263 161061.2737
CXB8/HiAJ m 536283.5 172762.6395 888635.2263 183931.7737
CXB9/HiAJ m 501633.9667 141060.1045 789327.9465 213939.9868
DBA/2J m 445919.9 122161.6339 695070.1951 196769.6049




  GWAS USING LINEAR MIXED MODELS