Project measure / variable:   CGDpheno3   QTc

ID, description, units MPD:43936   QTc   rate-corrected QT interval   [ms]  
Data set, strains CGDpheno3   CC diallel w/par   42 strains     sex: both     age: 12wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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CGDpheno3 - rate-corrected QT interval



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ — 51.7 51.1 43.4 — 45.8 45.9 47.5
A ♀ 50.3 41.4 44.0 50.7 44.2 45.4 — —
B6 ♀ 48.7 44.7 46.7 47.0 46.0 46.5 53.3 48.6
CAST ♀ 51.3 51.3 — — — 46.9 — —
NOD ♀ 49.5 43.6 45.7 49.5 46.0 46.3 45.6 —
NZO ♀ 46.7 43.8 45.7 — 43.5 47.6 — 46.7
PWK ♀ 45.9 47.4 44.9 — — 45.2 — —
WSB ♀ — 44.1 — — — 48.1 — —

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ — 51.9 — 50.1 — 47.2 45.9 46.5
A ♀ 50.1 46.0 45.9 — 41.2 44.9 — —
B6 ♀ 46.8 48.9 45.8 49.7 45.1 48.1 46.6 46.3
CAST ♀ 46.4 50.0 — — — 48.6 — —
NOD ♀ 49.2 44.4 45.0 50.1 47.0 45.1 46.0 —
NZO ♀ 47.2 44.4 46.9 — 46.1 48.3 — 44.7
PWK ♀ 45.8 44.6 46.2 — — 48.1 — —
WSB ♀ — — — — — 45.3 — —

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested42 strains39 strains
Mean of the strain means46.9   ms 46.8   ms
Median of the strain means46.4   ms 46.4   ms
SD of the strain means± 2.66 ± 2.12
Coefficient of variation (CV)0.0568 0.0452
Min–max range of strain means41.4   –   53.3   ms 41.2   –   51.9   ms
Mean sample size per strain4.8   mice 4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4.3697 4.3697 0.5461 0.4605
strain 38 1454.3241 38.2717 4.7834 < 0.0001
sex:strain 38 575.0426 15.1327 1.8914 0.0019
Residuals 306 2448.3046 8.001


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129SAF1 f 51.7 3.62   5 1.62 0.0701 46.8, 56.4 1.82
129SAF1 m 51.9 2.66   5 1.19 0.0513 49.1, 54.8 2.4
129SB6F1 f 51.1 3.07   5 1.37 0.06 46.2, 54.2 1.59
129SCASTF1 f 43.4 6.07   5 2.71 0.14 36.8, 51.7 -1.3
129SCASTF1 m 50.1 1.75   5 0.783 0.035 47.5, 52.3 1.55
129SNZOF1 f 45.8 1.02   7 0.387 0.0223 44.9, 47.9 -0.4
129SNZOF1 m 47.2 1.88   13 0.52 0.0397 44.5, 51.2 0.17
129SPWKF1 f 45.9 5.13   3 2.96 0.112 40.5, 50.7 -0.36
129SPWKF1 m 45.9 3.23   5 1.45 0.0704 42.6, 49.9 -0.44
129SWSBF1 f 47.5 1.91   2   1.35 0.0402 46.1, 48.8 0.24
129SWSBF1 m 46.5 0.212   2   0.15 0.00456 46.4, 46.7 -0.16
A129SF1 f 50.3 7.26   5 3.25 0.144 43.8, 61.2 1.29
A129SF1 m 50.1 1.01   5 0.453 0.0202 48.9, 51.5 1.55
AB6F1 f 44.0 1.52   5 0.679 0.0345 41.5, 45.4 -1.07
AB6F1 m 45.9 1.99   5 0.892 0.0434 44.1, 48.4 -0.44
ACASTF1 f 50.7 3.57   4 1.78 0.0703 47.8, 55.1 1.44
A/J f 41.4 3.89   5 1.74 0.094 35.7, 45.0 -2.05
A/J m 46.0 2.88   5 1.29 0.0625 42.6, 48.9 -0.39
ANODF1 f 44.2 2.69   5 1.2 0.0609 41.5, 48.0 -1.0
ANODF1 m 41.2 2.63   5 1.18 0.0639 38.4, 44.8 -2.66
ANZOF1 f 45.4 3.55   5 1.59 0.0782 41.4, 51.1 -0.55
ANZOF1 m 44.9 2.36   5 1.06 0.0526 42.3, 48.7 -0.91
B6129SF1/J f 48.7 1.84   5 0.822 0.0378 46.7, 51.4 0.69
B6129SF1/J m 46.8 1.91   5 0.852 0.0407 44.4, 48.8 -0.01
B6AF1/J f 44.7 3.49   5 1.56 0.0781 41.4, 50.4 -0.81
B6AF1/J m 48.9 3.95   5 1.77 0.0807 42.8, 53.1 0.98
B6CASTF1 f 47.0 1.66   5 0.744 0.0354 45.2, 49.3 0.05
B6CASTF1 m 49.7 2.14   5 0.957 0.0431 46.7, 51.9 1.36
B6NODF1 f 46.0 1.62   5 0.724 0.0352 43.9, 47.7 -0.32
B6NODF1 m 45.1 1.98   5 0.887 0.0439 42.0, 47.4 -0.82
B6NZOF1 f 46.5 2.18   5 0.973 0.0468 43.9, 49.7 -0.14
B6NZOF1 m 48.1 3.31   5 1.48 0.0688 45.6, 53.6 0.6
B6PWKF1 f 53.3 9.07   5 4.06 0.17 42.8, 63.3 2.42
B6PWKF1 m 46.6 2.75   5 1.23 0.0591 42.5, 49.6 -0.11
B6WSBF1 f 48.6 4.65   5 2.08 0.0958 41.3, 53.3 0.65
B6WSBF1 m 46.3 1.97   5 0.882 0.0426 44.2, 48.4 -0.25
C57BL/6J f 46.7 1.99   5 0.891 0.0427 45.4, 50.2 -0.06
C57BL/6J m 45.8 0.303   5 0.136 0.00663 45.5, 46.3 -0.49
CAST129SF1 f 51.3 3.52   5 1.58 0.0687 48.2, 57.3 1.67
CAST129SF1 m 46.4 4.76   5 2.13 0.103 37.9, 49.4 -0.2
CASTAF1 f 51.3 3.42   3 1.98 0.0667 47.4, 53.8 1.67
CASTAF1 m 50.0 2.42   5 1.08 0.0484 46.2, 52.6 1.5
CASTNZOF1 f 46.9 2.11   5 0.944 0.045 44.4, 49.5 0.01
CASTNZOF1 m 48.6 1.72   5 0.77 0.0355 46.4, 51.2 0.84
NOD129SF1 f 49.5 2.19   5 0.978 0.0442 47.7, 52.4 0.99
NOD129SF1 m 49.2 1.73   5 0.773 0.0351 46.2, 50.3 1.12
NODAF1 f 43.6 0.719   5 0.322 0.0165 42.5, 44.5 -1.23
NODAF1 m 44.4 2.59   5 1.16 0.0582 40.8, 47.6 -1.15
NODB6F1 f 45.7 2.11   5 0.943 0.0461 43.8, 49.1 -0.44
NODB6F1 m 45.0 1.07   5 0.48 0.0238 44.0, 46.8 -0.87
NODCASTF1 f 49.5 1.92   5 0.859 0.0388 46.4, 51.0 0.99
NODCASTF1 m 50.1 2.12   5 0.946 0.0422 47.4, 52.5 1.55
NODNZOF1 f 46.3 2.27   5 1.01 0.0489 43.6, 49.3 -0.21
NODNZOF1 m 45.1 2.57   5 1.15 0.0569 41.7, 48.9 -0.82
NODPWKF1 f 45.6 2.07   7 0.782 0.0454 43.2, 49.5 -0.47
NODPWKF1 m 46.0 2.12   5 0.947 0.046 43.1, 48.4 -0.39
NOD/ShiLtJ f 46.0 0.903   5 0.404 0.0196 45.0, 46.9 -0.32
NOD/ShiLtJ m 47.0 1.14   5 0.51 0.0243 45.5, 48.4 0.08
NZO129SF1 f 46.7 1.39   5 0.62 0.0297 45.2, 48.3 -0.06
NZO129SF1 m 47.2 2.21   5 0.987 0.0467 44.8, 50.4 0.17
NZOAF1 f 43.8 3.75   4 1.87 0.0856 41.1, 49.3 -1.15
NZOAF1 m 44.4 2.34   5 1.05 0.0528 41.9, 46.9 -1.15
NZOB6F1 f 45.7 1.51   5 0.676 0.0331 43.3, 47.2 -0.44
NZOB6F1 m 46.9 1.47   5 0.658 0.0314 45.2, 49.0 0.03
NZO/HlLtJ f 47.6 2.34   5 1.05 0.0492 45.2, 50.8 0.28
NZO/HlLtJ m 48.3 2.65   5 1.19 0.0549 46.0, 51.9 0.69
NZONODF1 f 43.5 1.13   5 0.505 0.026 42.0, 44.6 -1.26
NZONODF1 m 46.1 3.27   5 1.46 0.0709 42.4, 50.1 -0.35
NZOWSBF1 f 46.7 2.13   5 0.951 0.0455 45.0, 49.6 -0.06
NZOWSBF1 m 44.7 2.24   5 1.0 0.0502 41.4, 46.9 -1.01
PWK129SF1 f 45.9 4.38   5 1.96 0.0955 39.5, 49.4 -0.36
PWK129SF1 m 45.8 0.808   3 0.467 0.0176 45.1, 46.7 -0.49
PWKAF1 f 47.4 0.439   5 0.196 0.00928 46.8, 47.8 0.2
PWKAF1 m 44.6 1.58   5 0.705 0.0353 42.7, 46.2 -1.05
PWKB6F1 f 44.9 2.24   5 1.0 0.0498 41.0, 46.5 -0.74
PWKB6F1 m 46.2 2.08   5 0.93 0.045 43.0, 48.1 -0.3
PWKNZOF1 f 45.2 3.03   5 1.35 0.067 40.4, 48.6 -0.62
PWKNZOF1 m 48.1 2.37   3 1.37 0.0492 45.4, 49.6 0.6
WSBAF1 f 44.1 0.0   1   0.0 0.0 44.1, 44.1 -1.04
WSBNZOF1 f 48.1 0.569   3 0.328 0.0118 47.6, 48.7 0.47
WSBNZOF1 m 45.3 1.99   4 0.997 0.044 42.6, 47.3 -0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 f 51.66 1.265 54.1492 49.1708
129SAF1 m 51.9 1.265 54.3892 49.4108
129SCASTF1 f 43.38 1.265 45.8692 40.8908
129SCASTF1 m 50.06 1.265 52.5492 47.5708
129SNZOF1 f 45.8143 1.0691 47.918 43.7105
129SNZOF1 m 47.2 0.7845 48.7437 45.6563
129SPWKF1 f 45.9 1.6331 49.1135 42.6865
129SPWKF1 m 45.92 1.265 48.4092 43.4308
129SWSBF1 f 47.45 2.0001 51.3857 43.5143
129SWSBF1 m 46.55 2.0001 50.4857 42.6143
A129SF1 f 50.3 1.265 52.7892 47.8108
A129SF1 m 50.14 1.265 52.6292 47.6508
AB6F1 f 44.04 1.265 46.5292 41.5508
AB6F1 m 45.9 1.265 48.3892 43.4108
A/J f 41.42 1.265 43.9092 38.9308
A/J m 46.02 1.265 48.5092 43.5308
ANODF1 f 44.2 1.265 46.6892 41.7108
ANODF1 m 41.24 1.265 43.7292 38.7508
ANZOF1 f 45.38 1.265 47.8692 42.8908
ANZOF1 m 44.94 1.265 47.4292 42.4508
B6129SF1/J f 48.68 1.265 51.1692 46.1908
B6129SF1/J m 46.82 1.265 49.3092 44.3308
B6AF1/J f 44.66 1.265 47.1492 42.1708
B6AF1/J m 48.92 1.265 51.4092 46.4308
B6CASTF1 f 47.0 1.265 49.4892 44.5108
B6CASTF1 m 49.72 1.265 52.2092 47.2308
B6NODF1 f 45.96 1.265 48.4492 43.4708
B6NODF1 m 45.12 1.265 47.6092 42.6308
B6NZOF1 f 46.48 1.265 48.9692 43.9908
B6NZOF1 m 48.12 1.265 50.6092 45.6308
B6PWKF1 f 53.28 1.265 55.7692 50.7908
B6PWKF1 m 46.6 1.265 49.0892 44.1108
B6WSBF1 f 48.56 1.265 51.0492 46.0708
B6WSBF1 m 46.28 1.265 48.7692 43.7908
C57BL/6J f 46.66 1.265 49.1492 44.1708
C57BL/6J m 45.78 1.265 48.2692 43.2908
CAST129SF1 f 51.26 1.265 53.7492 48.7708
CAST129SF1 m 46.36 1.265 48.8492 43.8708
CASTAF1 f 51.3 1.6331 54.5135 48.0865
CASTAF1 m 50.04 1.265 52.5292 47.5508
CASTNZOF1 f 46.94 1.265 49.4292 44.4508
CASTNZOF1 m 48.58 1.265 51.0692 46.0908
NOD129SF1 f 49.5 1.265 51.9892 47.0108
NOD129SF1 m 49.22 1.265 51.7092 46.7308
NODAF1 f 43.62 1.265 46.1092 41.1308
NODAF1 m 44.42 1.265 46.9092 41.9308
NODB6F1 f 45.7 1.265 48.1892 43.2108
NODB6F1 m 45.02 1.265 47.5092 42.5308
NODCASTF1 f 49.54 1.265 52.0292 47.0508
NODCASTF1 m 50.1 1.265 52.5892 47.6108
NODNZOF1 f 46.34 1.265 48.8292 43.8508
NODNZOF1 m 45.1 1.265 47.5892 42.6108
NODPWKF1 f 45.6143 1.0691 47.718 43.5105
NODPWKF1 m 45.98 1.265 48.4692 43.4908
NOD/ShiLtJ f 46.0 1.265 48.4892 43.5108
NOD/ShiLtJ m 46.96 1.265 49.4492 44.4708
NZO129SF1 f 46.72 1.265 49.2092 44.2308
NZO129SF1 m 47.22 1.265 49.7092 44.7308
NZOAF1 f 43.75 1.4143 46.533 40.967
NZOAF1 m 44.36 1.265 46.8492 41.8708
NZOB6F1 f 45.74 1.265 48.2292 43.2508
NZOB6F1 m 46.92 1.265 49.4092 44.4308
NZO/HlLtJ f 47.56 1.265 50.0492 45.0708
NZO/HlLtJ m 48.28 1.265 50.7692 45.7908
NZONODF1 f 43.46 1.265 45.9492 40.9708
NZONODF1 m 46.08 1.265 48.5692 43.5908
NZOWSBF1 f 46.74 1.265 49.2292 44.2508
NZOWSBF1 m 44.7 1.265 47.1892 42.2108
PWK129SF1 f 45.92 1.265 48.4092 43.4308
PWK129SF1 m 45.8333 1.6331 49.0469 42.6198
PWKAF1 f 47.36 1.265 49.8492 44.8708
PWKAF1 m 44.64 1.265 47.1292 42.1508
PWKB6F1 f 44.92 1.265 47.4092 42.4308
PWKB6F1 m 46.18 1.265 48.6692 43.6908
PWKNZOF1 f 45.2 1.265 47.6892 42.7108
PWKNZOF1 m 48.1333 1.6331 51.3469 44.9198
WSBNZOF1 f 48.0667 1.6331 51.2802 44.8531
WSBNZOF1 m 45.325 1.4143 48.108 42.542


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 both 51.78 0.8945 53.5401 50.0199
129SCASTF1 both 46.72 0.8945 48.4801 44.9599
129SNZOF1 both 46.5071 0.663 47.8118 45.2025
129SPWKF1 both 45.91 1.0329 47.9424 43.8776
129SWSBF1 both 47.0 1.4143 49.783 44.217
A129SF1 both 50.22 0.8945 51.9801 48.4599
AB6F1 both 44.97 0.8945 46.7301 43.2099
A/J both 43.72 0.8945 45.4801 41.9599
ANODF1 both 42.72 0.8945 44.4801 40.9599
ANZOF1 both 45.16 0.8945 46.9201 43.3999
B6129SF1/J both 47.75 0.8945 49.5101 45.9899
B6AF1/J both 46.79 0.8945 48.5501 45.0299
B6CASTF1 both 48.36 0.8945 50.1201 46.5999
B6NODF1 both 45.54 0.8945 47.3001 43.7799
B6NZOF1 both 47.3 0.8945 49.0601 45.5399
B6PWKF1 both 49.94 0.8945 51.7001 48.1799
B6WSBF1 both 47.42 0.8945 49.1801 45.6599
C57BL/6J both 46.22 0.8945 47.9801 44.4599
CAST129SF1 both 48.81 0.8945 50.5701 47.0499
CASTAF1 both 50.67 1.0329 52.7024 48.6376
CASTNZOF1 both 47.76 0.8945 49.5201 45.9999
NOD129SF1 both 49.36 0.8945 51.1201 47.5999
NODAF1 both 44.02 0.8945 45.7801 42.2599
NODB6F1 both 45.36 0.8945 47.1201 43.5999
NODCASTF1 both 49.82 0.8945 51.5801 48.0599
NODNZOF1 both 45.72 0.8945 47.4801 43.9599
NODPWKF1 both 45.7971 0.8281 47.4267 44.1676
NOD/ShiLtJ both 46.48 0.8945 48.2401 44.7199
NZO129SF1 both 46.97 0.8945 48.7301 45.2099
NZOAF1 both 44.055 0.9487 45.9219 42.1881
NZOB6F1 both 46.33 0.8945 48.0901 44.5699
NZO/HlLtJ both 47.92 0.8945 49.6801 46.1599
NZONODF1 both 44.77 0.8945 46.5301 43.0099
NZOWSBF1 both 45.72 0.8945 47.4801 43.9599
PWK129SF1 both 45.8767 1.0329 47.9091 43.8443
PWKAF1 both 46.0 0.8945 47.7601 44.2399
PWKB6F1 both 45.55 0.8945 47.3101 43.7899
PWKNZOF1 both 46.6667 1.0329 48.6991 44.6343
WSBNZOF1 both 46.6958 1.0802 48.8214 44.5703




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA