Project measure / variable:   CGDpheno3   R_amplitude

ID, description, units MPD:43929   R_amplitude   R-wave amplitude   [mV]  
Data set, strains CGDpheno3   CC diallel w/par   42 strains     sex: both     age: 12wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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CGDpheno3 - R-wave amplitude



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ — 430 444 335 — 319 398 417
A ♀ 296 455 324 410 451 406 — —
B6 ♀ 393 283 435 355 386 361 344 314
CAST ♀ 341 360 — — — 291 — —
NOD ♀ 396 304 422 495 453 414 483 —
NZO ♀ 377 336 374 — 387 365 — 357
PWK ♀ 433 358 497 — — 377 — —
WSB ♀ — 323 — — — 351 — —

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ — 407 — 321 — 312 243 246
A ♀ 313 381 418 — 402 267 — —
B6 ♀ 284 348 411 441 394 351 284 297
CAST ♀ 281 327 — — — 434 — —
NOD ♀ 380 331 465 349 441 336 398 —
NZO ♀ 243 278 329 — 332 470 — 256
PWK ♀ 432 376 444 — — 633 — —
WSB ♀ — — — — — 221 — —

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested42 strains39 strains
Mean of the strain means382   mV 356   mV
Median of the strain means377   mV 348   mV
SD of the strain means± 55.7 ± 82.7
Coefficient of variation (CV)0.146 0.232
Min–max range of strain means283   –   497   mV 221   –   633   mV
Mean sample size per strain4.8   mice 4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 81739.1127 81739.1127 10.4211 0.0014
strain 38 1084059.7087 28527.8871 3.6371 < 0.0001
sex:strain 38 622623.4509 16384.8277 2.0889 0.0004
Residuals 306 2400143.1793 7843.6052


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129SAF1 f 430.0 86.3   5 38.6 0.201 289.0, 514.0 0.86
129SAF1 m 407.0 103.0   5 46.2 0.254 326.0, 582.0 0.62
129SB6F1 f 444.0 125.0   5 55.7 0.281 314.0, 646.0 1.11
129SCASTF1 f 335.0 79.0   5 35.3 0.236 262.0, 458.0 -0.85
129SCASTF1 m 321.0 60.8   5 27.2 0.19 235.0, 383.0 -0.42
129SNZOF1 f 319.0 87.8   7 33.2 0.275 206.0, 457.0 -1.13
129SNZOF1 m 312.0 88.0   13 24.4 0.282 239.0, 516.0 -0.53
129SPWKF1 f 398.0 105.0   3 60.6 0.264 299.0, 508.0 0.28
129SPWKF1 m 243.0 24.2   5 10.8 0.0996 212.0, 267.0 -1.36
129SWSBF1 f 417.0 84.6   2   59.8 0.203 357.0, 477.0 0.63
129SWSBF1 m 246.0 95.4   2   67.5 0.388 179.0, 313.0 -1.33
A129SF1 f 296.0 102.0   5 45.7 0.344 231.0, 475.0 -1.55
A129SF1 m 313.0 63.3   5 28.3 0.202 226.0, 379.0 -0.52
AB6F1 f 324.0 38.2   5 17.1 0.118 274.0, 377.0 -1.04
AB6F1 m 418.0 47.1   5 21.1 0.113 342.0, 466.0 0.75
ACASTF1 f 410.0 76.9   4 38.4 0.187 319.0, 495.0 0.5
A/J f 455.0 54.9   5 24.6 0.121 399.0, 527.0 1.31
A/J m 381.0 58.8   5 26.3 0.154 325.0, 466.0 0.3
ANODF1 f 451.0 119.0   5 53.4 0.265 374.0, 660.0 1.24
ANODF1 m 402.0 125.0   5 55.8 0.311 209.0, 554.0 0.56
ANZOF1 f 406.0 68.5   5 30.7 0.169 348.0, 488.0 0.43
ANZOF1 m 267.0 55.3   5 24.7 0.207 205.0, 350.0 -1.07
B6129SF1/J f 393.0 91.0   5 40.7 0.232 277.0, 514.0 0.19
B6129SF1/J m 284.0 70.8   5 31.7 0.25 229.0, 404.0 -0.87
B6AF1/J f 283.0 46.8   5 20.9 0.165 231.0, 338.0 -1.78
B6AF1/J m 348.0 42.8   5 19.2 0.123 299.0, 403.0 -0.09
B6CASTF1 f 355.0 80.2   5 35.9 0.226 238.0, 460.0 -0.49
B6CASTF1 m 441.0 82.9   5 37.1 0.188 328.0, 552.0 1.03
B6NODF1 f 386.0 54.5   5 24.4 0.141 319.0, 469.0 0.07
B6NODF1 m 394.0 82.1   5 36.7 0.209 256.0, 476.0 0.46
B6NZOF1 f 361.0 109.0   5 48.9 0.303 230.0, 510.0 -0.38
B6NZOF1 m 351.0 54.7   5 24.5 0.156 323.0, 449.0 -0.06
B6PWKF1 f 344.0 94.9   5 42.4 0.275 252.0, 503.0 -0.68
B6PWKF1 m 284.0 75.3   5 33.7 0.265 213.0, 406.0 -0.87
B6WSBF1 f 314.0 57.5   5 25.7 0.183 240.0, 401.0 -1.22
B6WSBF1 m 297.0 94.4   5 42.2 0.318 219.0, 451.0 -0.71
C57BL/6J f 435.0 155.0   5 69.1 0.355 269.0, 678.0 0.95
C57BL/6J m 411.0 34.9   5 15.6 0.0848 361.0, 453.0 0.67
CAST129SF1 f 341.0 78.2   5 35.0 0.229 263.0, 455.0 -0.74
CAST129SF1 m 281.0 83.2   5 37.2 0.296 220.0, 425.0 -0.9
CASTAF1 f 360.0 57.4   3 33.2 0.159 307.0, 421.0 -0.4
CASTAF1 m 327.0 55.4   5 24.8 0.17 246.0, 384.0 -0.35
CASTNZOF1 f 291.0 105.0   5 47.0 0.361 142.0, 432.0 -1.64
CASTNZOF1 m 434.0 155.0   5 69.4 0.357 281.0, 670.0 0.95
NOD129SF1 f 396.0 121.0   5 54.0 0.305 296.0, 559.0 0.25
NOD129SF1 m 380.0 116.0   5 51.8 0.305 282.0, 570.0 0.29
NODAF1 f 304.0 83.8   5 37.5 0.276 189.0, 372.0 -1.4
NODAF1 m 331.0 62.3   5 27.9 0.188 273.0, 424.0 -0.3
NODB6F1 f 422.0 69.8   5 31.2 0.165 348.0, 487.0 0.72
NODB6F1 m 465.0 56.6   5 25.3 0.122 376.0, 520.0 1.32
NODCASTF1 f 495.0 116.0   5 51.9 0.235 347.0, 594.0 2.02
NODCASTF1 m 349.0 210.0   5 94.0 0.602 0.42, 528.0 -0.08
NODNZOF1 f 414.0 101.0   5 45.1 0.244 308.0, 552.0 0.57
NODNZOF1 m 336.0 37.9   5 16.9 0.113 293.0, 388.0 -0.24
NODPWKF1 f 483.0 117.0   7 44.1 0.241 286.0, 645.0 1.81
NODPWKF1 m 398.0 111.0   5 49.7 0.279 292.0, 587.0 0.51
NOD/ShiLtJ f 453.0 65.3   5 29.2 0.144 370.0, 545.0 1.27
NOD/ShiLtJ m 441.0 78.5   5 35.1 0.178 356.0, 545.0 1.03
NZO129SF1 f 377.0 66.7   5 29.8 0.177 304.0, 458.0 -0.09
NZO129SF1 m 243.0 58.4   5 26.1 0.241 182.0, 323.0 -1.36
NZOAF1 f 336.0 57.3   4 28.7 0.171 298.0, 420.0 -0.83
NZOAF1 m 278.0 91.8   5 41.1 0.331 177.0, 386.0 -0.94
NZOB6F1 f 374.0 57.6   5 25.7 0.154 303.0, 447.0 -0.15
NZOB6F1 m 329.0 50.4   5 22.5 0.153 267.0, 370.0 -0.32
NZO/HlLtJ f 365.0 78.9   5 35.3 0.216 296.0, 455.0 -0.31
NZO/HlLtJ m 470.0 93.4   5 41.8 0.199 333.0, 580.0 1.38
NZONODF1 f 387.0 117.0   5 52.4 0.303 313.0, 594.0 0.09
NZONODF1 m 332.0 47.9   5 21.4 0.144 288.0, 408.0 -0.29
NZOWSBF1 f 357.0 90.9   5 40.7 0.255 232.0, 453.0 -0.45
NZOWSBF1 m 256.0 53.5   5 23.9 0.209 213.0, 329.0 -1.21
PWK129SF1 f 433.0 113.0   5 50.4 0.26 287.0, 598.0 0.91
PWK129SF1 m 432.0 62.3   3 36.0 0.144 376.0, 499.0 0.92
PWKAF1 f 358.0 129.0   5 57.5 0.359 274.0, 583.0 -0.43
PWKAF1 m 376.0 67.7   5 30.3 0.18 269.0, 436.0 0.24
PWKB6F1 f 497.0 153.0   5 68.6 0.309 397.0, 765.0 2.06
PWKB6F1 m 444.0 80.8   5 36.1 0.182 368.0, 561.0 1.07
PWKNZOF1 f 377.0 73.2   5 32.7 0.194 297.0, 485.0 -0.09
PWKNZOF1 m 633.0 98.9   3 57.1 0.156 544.0, 740.0 3.35
WSBAF1 f 323.0 0.0   1   0.0 0.0 323.0, 323.0 -1.06
WSBNZOF1 f 351.0 68.2   3 39.4 0.194 284.0, 421.0 -0.56
WSBNZOF1 m 221.0 16.8   4 8.42 0.0762 202.0, 239.0 -1.63


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 f 430.35 39.6071 508.2867 352.4133
129SAF1 m 406.994 39.6071 484.9307 329.0573
129SCASTF1 f 335.29 39.6071 413.2267 257.3533
129SCASTF1 m 320.772 39.6071 398.7087 242.8353
129SNZOF1 f 319.36 33.4741 385.2285 253.4915
129SNZOF1 m 311.7315 24.5633 360.0658 263.3972
129SPWKF1 f 398.1467 51.1325 498.7625 297.5308
129SPWKF1 m 242.546 39.6071 320.4827 164.6093
129SWSBF1 f 416.835 62.6243 540.0638 293.6062
129SWSBF1 m 246.02 62.6243 369.2488 122.7912
A129SF1 f 296.5 39.6071 374.4367 218.5633
A129SF1 m 312.506 39.6071 390.4427 234.5693
AB6F1 f 324.282 39.6071 402.2187 246.3453
AB6F1 m 417.582 39.6071 495.5187 339.6453
A/J f 454.74 39.6071 532.6767 376.8033
A/J m 380.758 39.6071 458.6947 302.8213
ANODF1 f 450.992 39.6071 528.9287 373.0553
ANODF1 m 401.652 39.6071 479.5887 323.7153
ANZOF1 f 405.936 39.6071 483.8727 327.9993
ANZOF1 m 267.154 39.6071 345.0907 189.2173
B6129SF1/J f 392.702 39.6071 470.6387 314.7653
B6129SF1/J m 283.568 39.6071 361.5047 205.6313
B6AF1/J f 282.816 39.6071 360.7527 204.8793
B6AF1/J m 347.746 39.6071 425.6827 269.8093
B6CASTF1 f 354.812 39.6071 432.7487 276.8753
B6CASTF1 m 441.026 39.6071 518.9627 363.0893
B6NODF1 f 386.096 39.6071 464.0327 308.1593
B6NODF1 m 393.99 39.6071 471.9267 316.0533
B6NZOF1 f 360.818 39.6071 438.7547 282.8813
B6NZOF1 m 351.476 39.6071 429.4127 273.5393
B6PWKF1 f 344.34 39.6071 422.2767 266.4033
B6PWKF1 m 283.924 39.6071 361.8607 205.9873
B6WSBF1 f 314.336 39.6071 392.2727 236.3993
B6WSBF1 m 297.086 39.6071 375.0227 219.1493
C57BL/6J f 435.042 39.6071 512.9787 357.1053
C57BL/6J m 411.048 39.6071 488.9847 333.1113
CAST129SF1 f 340.94 39.6071 418.8767 263.0033
CAST129SF1 m 280.844 39.6071 358.7807 202.9073
CASTAF1 f 360.1133 51.1325 460.7292 259.4975
CASTAF1 m 326.584 39.6071 404.5207 248.6473
CASTNZOF1 f 291.352 39.6071 369.2887 213.4153
CASTNZOF1 m 434.142 39.6071 512.0787 356.2053
NOD129SF1 f 395.672 39.6071 473.6087 317.7353
NOD129SF1 m 380.284 39.6071 458.2207 302.3473
NODAF1 f 303.86 39.6071 381.7967 225.9233
NODAF1 m 331.08 39.6071 409.0167 253.1433
NODB6F1 f 422.394 39.6071 500.3307 344.4573
NODB6F1 m 464.938 39.6071 542.8747 387.0013
NODCASTF1 f 494.562 39.6071 572.4987 416.6253
NODCASTF1 m 348.9 39.6071 426.8367 270.9633
NODNZOF1 f 413.62 39.6071 491.5567 335.6833
NODNZOF1 m 336.272 39.6071 414.2087 258.3353
NODPWKF1 f 482.7371 33.4741 548.6057 416.8686
NODPWKF1 m 398.454 39.6071 476.3907 320.5173
NOD/ShiLtJ f 453.478 39.6071 531.4147 375.5413
NOD/ShiLtJ m 441.124 39.6071 519.0607 363.1873
NZO129SF1 f 377.4 39.6071 455.3367 299.4633
NZO129SF1 m 242.562 39.6071 320.4987 164.6253
NZOAF1 f 335.865 44.2821 423.0009 248.7291
NZOAF1 m 277.74 39.6071 355.6767 199.8033
NZOB6F1 f 374.274 39.6071 452.2107 296.3373
NZOB6F1 m 328.566 39.6071 406.5027 250.6293
NZO/HlLtJ f 364.766 39.6071 442.7027 286.8293
NZO/HlLtJ m 469.536 39.6071 547.4727 391.5993
NZONODF1 f 387.12 39.6071 465.0567 309.1833
NZONODF1 m 332.28 39.6071 410.2167 254.3433
NZOWSBF1 f 356.914 39.6071 434.8507 278.9773
NZOWSBF1 m 256.448 39.6071 334.3847 178.5113
PWK129SF1 f 432.832 39.6071 510.7687 354.8953
PWK129SF1 m 432.2567 51.1325 532.8725 331.6408
PWKAF1 f 358.342 39.6071 436.2787 280.4053
PWKAF1 m 375.84 39.6071 453.7767 297.9033
PWKB6F1 f 496.512 39.6071 574.4487 418.5753
PWKB6F1 m 443.638 39.6071 521.5747 365.7013
PWKNZOF1 f 376.666 39.6071 454.6027 298.7293
PWKNZOF1 m 633.2333 51.1325 733.8492 532.6175
WSBNZOF1 f 351.3933 51.1325 452.0092 250.7775
WSBNZOF1 m 220.9025 44.2821 308.0384 133.7666


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 both 418.672 28.0064 473.7816 363.5624
129SCASTF1 both 328.031 28.0064 383.1406 272.9214
129SNZOF1 both 315.5458 20.7598 356.3957 274.6958
129SPWKF1 both 320.3463 32.339 383.9814 256.7113
129SWSBF1 both 331.4275 44.2821 418.5634 244.2916
A129SF1 both 304.503 28.0064 359.6126 249.3934
AB6F1 both 370.932 28.0064 426.0416 315.8224
A/J both 417.749 28.0064 472.8586 362.6394
ANODF1 both 426.322 28.0064 481.4316 371.2124
ANZOF1 both 336.545 28.0064 391.6546 281.4354
B6129SF1/J both 338.135 28.0064 393.2446 283.0254
B6AF1/J both 315.281 28.0064 370.3906 260.1714
B6CASTF1 both 397.919 28.0064 453.0286 342.8094
B6NODF1 both 390.043 28.0064 445.1526 334.9334
B6NZOF1 both 356.147 28.0064 411.2566 301.0374
B6PWKF1 both 314.132 28.0064 369.2416 259.0224
B6WSBF1 both 305.711 28.0064 360.8206 250.6014
C57BL/6J both 423.045 28.0064 478.1546 367.9354
CAST129SF1 both 310.892 28.0064 366.0016 255.7824
CASTAF1 both 343.3487 32.339 406.9837 279.7136
CASTNZOF1 both 362.747 28.0064 417.8566 307.6374
NOD129SF1 both 387.978 28.0064 443.0876 332.8684
NODAF1 both 317.47 28.0064 372.5796 262.3604
NODB6F1 both 443.666 28.0064 498.7756 388.5564
NODCASTF1 both 421.731 28.0064 476.8406 366.6214
NODNZOF1 both 374.946 28.0064 430.0556 319.8364
NODPWKF1 both 440.5956 25.9289 491.6171 389.574
NOD/ShiLtJ both 447.301 28.0064 502.4106 392.1914
NZO129SF1 both 309.981 28.0064 365.0906 254.8714
NZOAF1 both 306.8025 29.7053 365.255 248.35
NZOB6F1 both 351.42 28.0064 406.5296 296.3104
NZO/HlLtJ both 417.151 28.0064 472.2606 362.0414
NZONODF1 both 359.7 28.0064 414.8096 304.5904
NZOWSBF1 both 306.681 28.0064 361.7906 251.5714
PWK129SF1 both 432.5443 32.339 496.1794 368.9093
PWKAF1 both 367.091 28.0064 422.2006 311.9814
PWKB6F1 both 470.075 28.0064 525.1846 414.9654
PWKNZOF1 both 504.9497 32.339 568.5847 441.3146
WSBNZOF1 both 286.1479 33.821 352.6991 219.5968




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA