Project measure / variable:   CGDpheno3   CV

ID, description, units MPD:43928   CV   coefficient of variance, heart rate   [%]  
Data set, strains CGDpheno3   CC diallel w/par   42 strains     sex: both     age: 12wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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CGDpheno3 - coefficient of variance, heart rate



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 2.59 2.02 3.39 2.46 6.29 1.07
A ♀ 10.3 2.73 2.48 4.95 1.60 5.20
B6 ♀ 3.84 2.97 1.64 3.09 1.21 4.26 5.53 4.33
CAST ♀ 5.00 6.28 7.11
NOD ♀ 2.89 4.95 0.900 1.67 0.640 1.55 1.17
NZO ♀ 1.20 1.09 1.02 0.860 1.44 3.38
PWK ♀ 2.05 4.62 1.99 1.86
WSB ♀ 0.660 1.33

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 2.48 2.65 2.26 2.15 0.680
A ♀ 5.66 3.42 2.12 0.922 1.33
B6 ♀ 3.34 5.94 1.08 3.22 1.28 3.22 3.71 4.97
CAST ♀ 4.26 7.01 2.40
NOD ♀ 1.36 1.02 0.808 1.50 0.986 0.936 1.66
NZO ♀ 2.20 1.62 0.778 0.774 1.13 1.23
PWK ♀ 3.03 4.24 1.34 1.43
WSB ♀ 0.708

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested42 strains39 strains
Mean of the strain means2.99   % 2.33   %
Median of the strain means2.47   % 1.66   %
SD of the strain means± 2.10 ± 1.60
Coefficient of variation (CV)0.702 0.687
Min–max range of strain means0.640   –   10.3   % 0.680   –   7.01   %
Mean sample size per strain4.8   mice 4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 37.9102 37.9102 5.2732 0.0223
strain 38 1029.4656 27.0912 3.7683 < 0.0001
sex:strain 38 242.8844 6.3917 0.8891 0.6597
Residuals 306 2199.9121 7.1893


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129SAF1 f 2.59 0.858   5 0.384 0.331 1.49, 3.65 -0.19
129SAF1 m 2.48 1.53   5 0.684 0.616 0.64, 4.11 0.09
129SB6F1 f 2.02 1.58   5 0.705 0.78 0.62, 4.64 -0.46
129SCASTF1 f 3.39 0.82   5 0.367 0.242 2.95, 4.85 0.19
129SCASTF1 m 2.65 1.66   5 0.74 0.624 0.78, 4.59 0.2
129SNZOF1 f 2.46 2.22   7 0.839 0.903 0.88, 7.28 -0.25
129SNZOF1 m 2.26 1.38   13 0.383 0.612 0.62, 5.04 -0.04
129SPWKF1 f 6.29 4.93   3 2.85 0.784 1.58, 11.4 1.57
129SPWKF1 m 2.15 1.15   5 0.515 0.536 0.96, 3.86 -0.11
129SWSBF1 f 1.07 0.127   2   0.09 0.119 0.98, 1.16 -0.92
129SWSBF1 m 0.68 0.0141   2   0.01 0.0208 0.67, 0.69 -1.03
A129SF1 f 10.3 7.34   5 3.28 0.71 1.53, 18.8 3.48
A129SF1 m 5.66 2.56   5 1.15 0.453 1.63, 7.72 2.08
AB6F1 f 2.48 2.15   5 0.959 0.866 0.75, 6.12 -0.24
AB6F1 m 2.12 0.984   5 0.44 0.463 1.31, 3.6 -0.13
ACASTF1 f 4.95 5.15   4 2.58 1.04 1.0, 12.5 0.93
A/J f 2.73 2.23   5 0.998 0.818 0.46, 5.94 -0.12
A/J m 3.42 4.61   5 2.06 1.35 0.72, 11.5 0.68
ANODF1 f 1.6 1.14   5 0.511 0.712 0.63, 3.48 -0.66
ANODF1 m 0.922 0.666   5 0.298 0.722 0.55, 2.11 -0.88
ANZOF1 f 5.2 6.7   5 3.0 1.29 1.12, 17.1 1.05
ANZOF1 m 1.33 0.734   5 0.328 0.553 0.67, 2.35 -0.62
B6129SF1/J f 3.84 2.46   5 1.1 0.642 2.33, 8.17 0.4
B6129SF1/J m 3.34 3.09   5 1.38 0.925 0.68, 7.23 0.63
B6AF1/J f 2.97 2.03   5 0.908 0.683 0.86, 5.44 -0.01
B6AF1/J m 5.94 6.83   5 3.06 1.15 1.16, 18.0 2.25
B6CASTF1 f 3.09 1.02   5 0.455 0.329 1.87, 4.3 0.05
B6CASTF1 m 3.22 0.133   5 0.0594 0.0413 3.04, 3.37 0.56
B6NODF1 f 1.21 0.488   5 0.218 0.404 0.73, 1.71 -0.85
B6NODF1 m 1.28 0.556   5 0.249 0.435 0.76, 1.92 -0.66
B6NZOF1 f 4.26 4.66   5 2.08 1.09 0.91, 11.9 0.6
B6NZOF1 m 3.22 3.21   5 1.43 0.997 1.41, 8.89 0.56
B6PWKF1 f 5.53 2.87   5 1.28 0.52 1.17, 8.63 1.21
B6PWKF1 m 3.71 3.88   5 1.74 1.05 1.03, 10.3 0.86
B6WSBF1 f 4.33 1.25   5 0.557 0.288 3.32, 6.36 0.64
B6WSBF1 m 4.97 3.78   5 1.69 0.76 1.14, 10.6 1.65
C57BL/6J f 1.64 0.336   5 0.15 0.205 1.2, 2.1 -0.64
C57BL/6J m 1.08 0.766   5 0.343 0.708 0.48, 2.34 -0.78
CAST129SF1 f 5.0 4.19   5 1.87 0.838 1.35, 10.1 0.96
CAST129SF1 m 4.26 4.64   5 2.07 1.09 0.74, 10.7 1.21
CASTAF1 f 6.28 4.34   3 2.51 0.691 2.8, 11.2 1.57
CASTAF1 m 7.01 4.05   5 1.81 0.578 2.02, 12.3 2.92
CASTNZOF1 f 7.11 8.58   5 3.84 1.21 0.97, 20.4 1.96
CASTNZOF1 m 2.4 2.35   5 1.05 0.982 0.74, 6.51 0.04
NOD129SF1 f 2.89 3.29   5 1.47 1.14 0.95, 8.74 -0.05
NOD129SF1 m 1.36 0.513   5 0.229 0.376 0.63, 2.01 -0.61
NODAF1 f 4.95 3.57   5 1.6 0.721 1.66, 10.2 0.93
NODAF1 m 1.02 0.508   5 0.227 0.5 0.55, 1.88 -0.82
NODB6F1 f 0.9 0.181   5 0.0807 0.201 0.65, 1.15 -1.0
NODB6F1 m 0.808 0.233   5 0.104 0.288 0.57, 1.19 -0.95
NODCASTF1 f 1.67 0.581   5 0.26 0.347 0.82, 2.31 -0.63
NODCASTF1 m 1.5 0.565   5 0.253 0.377 0.63, 2.14 -0.52
NODNZOF1 f 1.55 0.954   5 0.427 0.616 0.65, 3.12 -0.69
NODNZOF1 m 0.936 0.241   5 0.108 0.257 0.59, 1.2 -0.87
NODPWKF1 f 1.17 0.521   7 0.197 0.445 0.41, 1.89 -0.87
NODPWKF1 m 1.66 1.0   5 0.449 0.605 0.57, 2.95 -0.42
NOD/ShiLtJ f 0.64 0.127   5 0.0567 0.198 0.48, 0.81 -1.12
NOD/ShiLtJ m 0.986 0.633   5 0.283 0.642 0.46, 2.01 -0.84
NZO129SF1 f 1.2 0.191   5 0.0854 0.16 0.93, 1.42 -0.85
NZO129SF1 m 2.2 2.91   5 1.3 1.32 0.49, 7.32 -0.08
NZOAF1 f 1.09 0.386   4 0.193 0.354 0.6, 1.45 -0.91
NZOAF1 m 1.62 1.12   5 0.503 0.693 0.87, 3.49 -0.44
NZOB6F1 f 1.02 0.201   5 0.0899 0.197 0.76, 1.27 -0.94
NZOB6F1 m 0.778 0.178   5 0.0795 0.228 0.48, 0.95 -0.97
NZO/HlLtJ f 1.44 1.51   5 0.673 1.05 0.54, 4.08 -0.74
NZO/HlLtJ m 1.13 1.23   5 0.549 1.09 0.54, 3.32 -0.75
NZONODF1 f 0.86 0.208   5 0.093 0.242 0.65, 1.15 -1.02
NZONODF1 m 0.774 0.258   5 0.115 0.333 0.56, 1.19 -0.97
NZOWSBF1 f 3.38 2.85   5 1.27 0.844 0.68, 7.95 0.19
NZOWSBF1 m 1.23 1.27   5 0.569 1.03 0.61, 3.51 -0.69
PWK129SF1 f 2.05 1.02   5 0.455 0.495 0.72, 3.34 -0.45
PWK129SF1 m 3.03 2.23   3 1.29 0.735 0.46, 4.32 0.44
PWKAF1 f 4.62 4.15   5 1.86 0.899 0.61, 10.0 0.78
PWKAF1 m 4.24 4.44   5 1.99 1.05 0.91, 12.0 1.19
PWKB6F1 f 1.99 0.726   5 0.325 0.364 1.23, 3.12 -0.48
PWKB6F1 m 1.34 0.545   5 0.244 0.408 0.68, 2.1 -0.62
PWKNZOF1 f 1.86 0.818   5 0.366 0.439 0.83, 3.04 -0.54
PWKNZOF1 m 1.43 0.691   3 0.399 0.482 0.86, 2.2 -0.56
WSBAF1 f 0.66 0.0   1   0.0 0.0 0.66, 0.66 -1.11
WSBNZOF1 f 1.33 0.531   3 0.307 0.399 0.89, 1.92 -0.79
WSBNZOF1 m 0.708 0.248   4 0.124 0.351 0.51, 1.05 -1.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 f 2.592 1.1991 4.9515 0.2325
129SAF1 m 2.484 1.1991 4.8435 0.1245
129SCASTF1 f 3.39 1.1991 5.7495 1.0305
129SCASTF1 m 2.654 1.1991 5.0135 0.2945
129SNZOF1 f 2.46 1.0134 4.4542 0.4658
129SNZOF1 m 2.2554 0.7437 3.7187 0.7921
129SPWKF1 f 6.29 1.548 9.3361 3.2439
129SPWKF1 m 2.148 1.1991 4.5075 0.0
129SWSBF1 f 1.07 1.896 4.8008 0.0
129SWSBF1 m 0.68 1.896 4.4108 0.0
A129SF1 f 10.34 1.1991 12.6995 7.9805
A129SF1 m 5.66 1.1991 8.0195 3.3005
AB6F1 f 2.476 1.1991 4.8355 0.1165
AB6F1 m 2.124 1.1991 4.4835 0.0
A/J f 2.73 1.1991 5.0895 0.3705
A/J m 3.418 1.1991 5.7775 1.0585
ANODF1 f 1.604 1.1991 3.9635 0.0
ANODF1 m 0.922 1.1991 3.2815 0.0
ANZOF1 f 5.2 1.1991 7.5595 2.8405
ANZOF1 m 1.328 1.1991 3.6875 0.0
B6129SF1/J f 3.84 1.1991 6.1995 1.4805
B6129SF1/J m 3.344 1.1991 5.7035 0.9845
B6AF1/J f 2.972 1.1991 5.3315 0.6125
B6AF1/J m 5.938 1.1991 8.2975 3.5785
B6CASTF1 f 3.088 1.1991 5.4475 0.7285
B6CASTF1 m 3.222 1.1991 5.5815 0.8625
B6NODF1 f 1.21 1.1991 3.5695 0.0
B6NODF1 m 1.278 1.1991 3.6375 0.0
B6NZOF1 f 4.256 1.1991 6.6155 1.8965
B6NZOF1 m 3.216 1.1991 5.5755 0.8565
B6PWKF1 f 5.528 1.1991 7.8875 3.1685
B6PWKF1 m 3.712 1.1991 6.0715 1.3525
B6WSBF1 f 4.33 1.1991 6.6895 1.9705
B6WSBF1 m 4.974 1.1991 7.3335 2.6145
C57BL/6J f 1.64 1.1991 3.9995 0.0
C57BL/6J m 1.082 1.1991 3.4415 0.0
CAST129SF1 f 4.998 1.1991 7.3575 2.6385
CAST129SF1 m 4.262 1.1991 6.6215 1.9025
CASTAF1 f 6.2833 1.548 9.3295 3.2372
CASTAF1 m 7.012 1.1991 9.3715 4.6525
CASTNZOF1 f 7.11 1.1991 9.4695 4.7505
CASTNZOF1 m 2.396 1.1991 4.7555 0.0365
NOD129SF1 f 2.89 1.1991 5.2495 0.5305
NOD129SF1 m 1.364 1.1991 3.7235 0.0
NODAF1 f 4.952 1.1991 7.3115 2.5925
NODAF1 m 1.016 1.1991 3.3755 0.0
NODB6F1 f 0.9 1.1991 3.2595 0.0
NODB6F1 m 0.808 1.1991 3.1675 0.0
NODCASTF1 f 1.672 1.1991 4.0315 0.0
NODCASTF1 m 1.496 1.1991 3.8555 0.0
NODNZOF1 f 1.548 1.1991 3.9075 0.0
NODNZOF1 m 0.936 1.1991 3.2955 0.0
NODPWKF1 f 1.1714 1.0134 3.1656 0.0
NODPWKF1 m 1.658 1.1991 4.0175 0.0
NOD/ShiLtJ f 0.64 1.1991 2.9995 0.0
NOD/ShiLtJ m 0.986 1.1991 3.3455 0.0
NZO129SF1 f 1.196 1.1991 3.5555 0.0
NZO129SF1 m 2.2 1.1991 4.5595 0.0
NZOAF1 f 1.09 1.3406 3.728 0.0
NZOAF1 m 1.622 1.1991 3.9815 0.0
NZOB6F1 f 1.02 1.1991 3.3795 0.0
NZOB6F1 m 0.778 1.1991 3.1375 0.0
NZO/HlLtJ f 1.438 1.1991 3.7975 0.0
NZO/HlLtJ m 1.126 1.1991 3.4855 0.0
NZONODF1 f 0.86 1.1991 3.2195 0.0
NZONODF1 m 0.774 1.1991 3.1335 0.0
NZOWSBF1 f 3.376 1.1991 5.7355 1.0165
NZOWSBF1 m 1.234 1.1991 3.5935 0.0
PWK129SF1 f 2.052 1.1991 4.4115 0.0
PWK129SF1 m 3.03 1.548 6.0761 0.0
PWKAF1 f 4.622 1.1991 6.9815 2.2625
PWKAF1 m 4.242 1.1991 6.6015 1.8825
PWKB6F1 f 1.994 1.1991 4.3535 0.0
PWKB6F1 m 1.336 1.1991 3.6955 0.0
PWKNZOF1 f 1.862 1.1991 4.2215 0.0
PWKNZOF1 m 1.4333 1.548 4.4795 0.0
WSBNZOF1 f 1.33 1.548 4.3761 0.0
WSBNZOF1 m 0.7075 1.3406 3.3455 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 both 2.538 0.8479 4.2064 0.8696
129SCASTF1 both 3.022 0.8479 4.6904 1.3536
129SNZOF1 both 2.3577 0.6285 3.5944 1.121
129SPWKF1 both 4.219 0.9791 6.1456 2.2924
129SWSBF1 both 0.875 1.3406 3.513 0.0
A129SF1 both 8.0 0.8479 9.6684 6.3316
AB6F1 both 2.3 0.8479 3.9684 0.6316
A/J both 3.074 0.8479 4.7424 1.4056
ANODF1 both 1.263 0.8479 2.9314 0.0
ANZOF1 both 3.264 0.8479 4.9324 1.5956
B6129SF1/J both 3.592 0.8479 5.2604 1.9236
B6AF1/J both 4.455 0.8479 6.1234 2.7866
B6CASTF1 both 3.155 0.8479 4.8234 1.4866
B6NODF1 both 1.244 0.8479 2.9124 0.0
B6NZOF1 both 3.736 0.8479 5.4044 2.0676
B6PWKF1 both 4.62 0.8479 6.2884 2.9516
B6WSBF1 both 4.652 0.8479 6.3204 2.9836
C57BL/6J both 1.361 0.8479 3.0294 0.0
CAST129SF1 both 4.63 0.8479 6.2984 2.9616
CASTAF1 both 6.6477 0.9791 8.5742 4.7211
CASTNZOF1 both 4.753 0.8479 6.4214 3.0846
NOD129SF1 both 2.127 0.8479 3.7954 0.4586
NODAF1 both 2.984 0.8479 4.6524 1.3156
NODB6F1 both 0.854 0.8479 2.5224 0.0
NODCASTF1 both 1.584 0.8479 3.2524 0.0
NODNZOF1 both 1.242 0.8479 2.9104 0.0
NODPWKF1 both 1.4147 0.785 2.9594 0.0
NOD/ShiLtJ both 0.813 0.8479 2.4814 0.0
NZO129SF1 both 1.698 0.8479 3.3664 0.0296
NZOAF1 both 1.356 0.8993 3.1257 0.0
NZOB6F1 both 0.899 0.8479 2.5674 0.0
NZO/HlLtJ both 1.282 0.8479 2.9504 0.0
NZONODF1 both 0.817 0.8479 2.4854 0.0
NZOWSBF1 both 2.305 0.8479 3.9734 0.6366
PWK129SF1 both 2.541 0.9791 4.4676 0.6144
PWKAF1 both 4.432 0.8479 6.1004 2.7636
PWKB6F1 both 1.665 0.8479 3.3334 0.0
PWKNZOF1 both 1.6477 0.9791 3.5742 0.0
WSBNZOF1 both 1.0188 1.0239 3.0336 0.0




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA