Project measure / variable:   CGDpheno3   systolic_BP


  STRAIN COMPARISON PLOT
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CGDpheno3 - systolic blood pressure



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 114 122 135
A ♀ 111 118
B6 ♀ 123 108 140 126
CAST ♀
NOD ♀ 134 124 108
NZO ♀ 124 134 139 118
PWK ♀ 120 111
WSB ♀ 140 142

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 110 123 128 109
A ♀ 128 104 119
B6 ♀ 127 109 145 118
CAST ♀
NOD ♀ 132 124 106 130
NZO ♀ 131 122 124 117
PWK ♀ 131 106
WSB ♀ 120 136 127

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested20 strains24 strains
Mean of the strain means125   mmHg 122   mmHg
Median of the strain means124   mmHg 124   mmHg
SD of the strain means± 11.3 ± 10.5
Coefficient of variation (CV)0.0907 0.0864
Min–max range of strain means108   –   142   mmHg 104   –   145   mmHg
Mean sample size per strain4.6   mice 4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 701.7815 701.7815 2.3745 0.1259
strain 17 15289.322 899.3719 3.0431 0.0002
sex:strain 17 5599.9744 329.4103 1.1146 0.3478
Residuals 122 36056.6052 295.5459


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129SAF1 f 114.0 38.2   5 17.1 0.335 66.6, 161.0 -0.93
129SAF1 m 110.0 26.7   5 12.0 0.243 76.1, 136.0 -1.13
129SB6F1 m 123.0 9.56   5 4.27 0.0779 112.0, 135.0 0.1
129SNZOF1 f 122.0 9.19   2   6.5 0.075 116.0, 129.0 -0.23
129SNZOF1 m 128.0 14.3   6 5.84 0.112 105.0, 144.0 0.58
129SWSBF1 f 135.0 22.3   5 9.96 0.165 113.0, 170.0 0.93
129SWSBF1 m 109.0 8.72   5 3.9 0.0803 96.7, 119.0 -1.23
A129SF1 f 111.0 9.45   5 4.23 0.0851 97.6, 122.0 -1.2
A129SF1 m 128.0 23.5   5 10.5 0.183 95.1, 154.0 0.58
AB6F1 f 118.0 11.0   5 4.92 0.0928 105.0, 131.0 -0.58
AB6F1 m 104.0 18.8   5 8.39 0.181 74.2, 119.0 -1.7
AWSBF1 m 119.0 9.95   5 4.45 0.0836 107.0, 132.0 -0.28
B6129SF1/J f 123.0 7.95   5 3.56 0.0645 115.0, 133.0 -0.14
B6129SF1/J m 127.0 20.6   3 11.9 0.162 104.0, 143.0 0.48
B6AF1/J f 108.0 11.0   5 4.91 0.102 93.2, 123.0 -1.47
B6AF1/J m 109.0 12.3   5 5.5 0.112 94.2, 125.0 -1.23
B6NODF1 f 140.0 7.11   5 3.18 0.0508 131.0, 150.0 1.37
B6NODF1 m 145.0 12.5   5 5.58 0.0863 124.0, 158.0 2.19
B6NZOF1 f 126.0 6.88   5 3.08 0.0544 116.0, 134.0 0.13
B6NZOF1 m 118.0 10.5   5 4.72 0.0895 107.0, 135.0 -0.37
NOD129SF1 f 134.0 18.3   5 8.18 0.137 114.0, 153.0 0.84
NOD129SF1 m 132.0 16.4   5 7.32 0.124 106.0, 147.0 0.96
NODAF1 m 124.0 14.0   5 6.27 0.113 111.0, 145.0 0.2
NODNZOF1 f 124.0 13.6   4 6.81 0.11 111.0, 143.0 -0.05
NODNZOF1 m 106.0 29.9   4 14.9 0.283 63.0, 132.0 -1.51
NODPWKF1 f 108.0 26.1   3 15.0 0.241 81.9, 134.0 -1.47
NODPWKF1 m 130.0 16.4   4 8.21 0.126 115.0, 150.0 0.77
NZO129SF1 f 124.0 9.46   5 4.23 0.0763 108.0, 131.0 -0.05
NZO129SF1 m 131.0 0.0   1   0.0 0.0 131.0, 131.0 0.86
NZOAF1 f 134.0 10.8   4 5.39 0.0808 121.0, 143.0 0.84
NZOAF1 m 122.0 19.2   5 8.58 0.158 94.8, 143.0 0.01
NZOB6F1 f 139.0 8.65   5 3.87 0.0624 124.0, 146.0 1.28
NZOB6F1 m 124.0 11.2   4 5.62 0.0903 110.0, 136.0 0.2
NZONODF1 f 118.0 16.1   4 8.06 0.136 95.6, 132.0 -0.58
NZONODF1 m 117.0 22.1   4 11.0 0.188 93.3, 138.0 -0.47
PWKCASTF1 f 120.0 9.43   4 4.71 0.0787 109.0, 131.0 -0.4
PWKCASTF1 m 131.0 0.0   1   0.0 0.0 131.0, 131.0 0.86
PWKNZOF1 f 111.0 15.4   5 6.89 0.139 90.9, 127.0 -1.2
PWKNZOF1 m 106.0 21.6   2   15.2 0.204 90.5, 121.0 -1.51
WSB129SF1 f 140.0 19.4   3 11.2 0.139 123.0, 161.0 1.37
WSB129SF1 m 120.0 5.57   3 3.21 0.0464 114.0, 125.0 -0.18
WSBB6F1 f 142.0 15.9   5 7.09 0.111 128.0, 167.0 1.55
WSBB6F1 m 136.0 6.08   3 3.51 0.0447 129.0, 140.0 1.34
WSBNZOF1 m 127.0 12.6   4 6.32 0.0993 109.0, 138.0 0.48


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 f 114.24 7.6883 129.4597 99.0203
129SAF1 m 109.98 7.6883 125.1997 94.7603
129SNZOF1 f 122.5 12.1562 146.5644 98.4356
129SNZOF1 m 127.8333 7.0184 141.7269 113.9397
129SWSBF1 f 134.8 7.6883 150.0197 119.5803
129SWSBF1 m 108.54 7.6883 123.7597 93.3203
A129SF1 f 111.12 7.6883 126.3397 95.9003
A129SF1 m 128.42 7.6883 143.6397 113.2003
AB6F1 f 118.4 7.6883 133.6197 103.1803
AB6F1 m 103.54 7.6883 118.7597 88.3203
B6129SF1/J f 123.2 7.6883 138.4197 107.9803
B6129SF1/J m 127.3333 9.9255 146.9818 107.6848
B6AF1/J f 108.04 7.6883 123.2597 92.8203
B6AF1/J m 109.44 7.6883 124.6597 94.2203
B6NODF1 f 140.0 7.6883 155.2197 124.7803
B6NODF1 m 144.6 7.6883 159.8197 129.3803
B6NZOF1 f 126.4 7.6883 141.6197 111.1803
B6NZOF1 m 117.8 7.6883 133.0197 102.5803
NOD129SF1 f 133.6 7.6883 148.8197 118.3803
NOD129SF1 m 132.2 7.6883 147.4197 116.9803
NODNZOF1 f 124.0 8.5957 141.0161 106.9839
NODNZOF1 m 105.5 8.5957 122.5161 88.4839
NODPWKF1 f 108.3 9.9255 127.9485 88.6515
NODPWKF1 m 130.5 8.5957 147.5161 113.4839
NZOAF1 f 133.5 8.5957 150.5161 116.4839
NZOAF1 m 121.76 7.6883 136.9797 106.5403
NZOB6F1 f 138.6 7.6883 153.8197 123.3803
NZOB6F1 m 124.5 8.5957 141.5161 107.4839
NZONODF1 f 118.15 8.5957 135.1661 101.1339
NZONODF1 m 117.325 8.5957 134.3411 100.3089
PWKNZOF1 f 110.9 7.6883 126.1197 95.6803
PWKNZOF1 m 105.75 12.1562 129.8144 81.6856
WSB129SF1 f 139.6667 9.9255 159.3152 120.0182
WSB129SF1 m 120.0 9.9255 139.6485 100.3515
WSBB6F1 f 142.4 7.6883 157.6197 127.1803
WSBB6F1 m 136.0 9.9255 155.6485 116.3515


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 both 112.11 5.4364 122.8719 101.3481
129SNZOF1 both 125.1667 7.0184 139.0603 111.2731
129SWSBF1 both 121.67 5.4364 132.4319 110.9081
A129SF1 both 119.77 5.4364 130.5319 109.0081
AB6F1 both 110.97 5.4364 121.7319 100.2081
B6129SF1/J both 125.2667 6.2774 137.6935 112.8399
B6AF1/J both 108.74 5.4364 119.5019 97.9781
B6NODF1 both 142.3 5.4364 153.0619 131.5381
B6NZOF1 both 122.1 5.4364 132.8619 111.3381
NOD129SF1 both 132.9 5.4364 143.6619 122.1381
NODNZOF1 both 114.75 6.0781 126.7822 102.7178
NODPWKF1 both 119.4 6.5651 132.3963 106.4037
NZOAF1 both 127.63 5.7662 139.0447 116.2153
NZOB6F1 both 131.55 5.7662 142.9647 120.1353
NZONODF1 both 117.7375 6.0781 129.7697 105.7053
PWKNZOF1 both 108.325 7.1917 122.5617 94.0883
WSB129SF1 both 129.8333 7.0184 143.7269 115.9397
WSBB6F1 both 139.2 6.2774 151.6268 126.7732




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA