Project measure / variable:   Chang2   retinal_spots

ID, description, units MPD:42704   retinal_spots   retinal spots (multifocal circumscribed areas of hypopigmentation)   [frequency rate]  
Data set, strains Chang2   B6.PWD consomic w/par   28 strains     sex: both     age: 44-61wks
Procedure ophthalmoscopy
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  STRAIN COMPARISON PLOT
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Chang2 - retinal spots (multifocal circumscribed areas of hypopigmentation)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means0.0534   frequency rate 0.0410   frequency rate
Median of the strain means0   frequency rate 0   frequency rate
SD of the strain means± 0.101 ± 0.0770
Coefficient of variation (CV)1.89 1.88
Min–max range of strain means0   –   0.375   frequency rate 0   –   0.333   frequency rate
Mean sample size per strain8.8   mice 8.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0044 0.0044 0.1068 0.744
strain 27 3.2756 0.1213 2.9554 < 0.0001
sex:strain 27 0.3066 0.0114 0.2766 0.9999
Residuals 424 17.4052 0.041


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 0.375 0.518   8 0.183 1.38 3.2
B6.PWD-Chr1 m 0.333 0.5   9 0.167 1.5 3.79
B6.PWD-Chr10.1 f 0.125 0.354   8 0.125 2.83 0.71
B6.PWD-Chr10.1 m 0.1 0.316   10 0.1 3.16 0.77
B6.PWD-Chr10.2 f 0.0 0.0   10 0.0 0.0 -0.53
B6.PWD-Chr10.2 m 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr10.3 f 0.0 0.0   7 0.0 0.0 -0.53
B6.PWD-Chr10.3 m 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr11.1 f 0.125 0.354   8 0.125 2.83 0.71
B6.PWD-Chr11.1 m 0.125 0.354   8 0.125 2.83 1.09
B6.PWD-Chr11.2 f 0.0 0.0   7 0.0 0.0 -0.53
B6.PWD-Chr11.2 m 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr11.3 f 0.286 0.488   7 0.184 1.71 2.31
B6.PWD-Chr11.3 m 0.111 0.333   9 0.111 3.0 0.91
B6.PWD-Chr12 f 0.111 0.333   9 0.111 3.0 0.57
B6.PWD-Chr12 m 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr13 f 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr13 m 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr14 f 0.0 0.0   9 0.0 0.0 -0.53
B6.PWD-Chr14 m 0.0 0.0   9 0.0 0.0 -0.53
B6.PWD-Chr15 f 0.111 0.333   9 0.111 3.0 0.57
B6.PWD-Chr15 m 0.125 0.354   8 0.125 2.83 1.09
B6.PWD-Chr16 f 0.0 0.0   11 0.0 0.0 -0.53
B6.PWD-Chr16 m 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr17 f 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr17 m 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr18 f 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr18 m 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr19 f 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr19 m 0.0 0.0   9 0.0 0.0 -0.53
B6.PWD-Chr2 f 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr2 m 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr3 f 0.25 0.463   8 0.164 1.85 1.95
B6.PWD-Chr3 m 0.111 0.333   9 0.111 3.0 0.91
B6.PWD-Chr5 f 0.0 0.0   10 0.0 0.0 -0.53
B6.PWD-Chr5 m 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-Chr6 f 0.111 0.333   9 0.111 3.0 0.57
B6.PWD-Chr6 m 0.143 0.378   7 0.143 2.65 1.32
B6.PWD-Chr8 f 0.0 0.0   11 0.0 0.0 -0.53
B6.PWD-Chr8 m 0.1 0.316   10 0.1 3.16 0.77
B6.PWD-Chr9 f 0.0 0.0   11 0.0 0.0 -0.53
B6.PWD-Chr9 m 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-ChrX.1 f 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-ChrX.1 m 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-ChrX.2 f 0.0 0.0   10 0.0 0.0 -0.53
B6.PWD-ChrX.2 m 0.0 0.0   10 0.0 0.0 -0.53
B6.PWD-ChrX.3 f 0.0 0.0   9 0.0 0.0 -0.53
B6.PWD-ChrX.3 m 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-ChrY f 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-ChrY m 0.0 0.0   8 0.0 0.0 -0.53
B6.PWD-mt f 0.0 0.0   9 0.0 0.0 -0.53
B6.PWD-mt m 0.0 0.0   8 0.0 0.0 -0.53
C57BL/6J f 0.0 0.0   9 0.0 0.0 -0.53
C57BL/6J m 0.0 0.0   9 0.0 0.0 -0.53
PWD/PhJ f 0.0 0.0   11 0.0 0.0 -0.53
PWD/PhJ m 0.0 0.0   7 0.0 0.0 -0.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 0.375 0.0716 0.5158 0.2342
B6.PWD-Chr1 m 0.3333 0.0675 0.4661 0.2006
B6.PWD-Chr10.1 f 0.125 0.0716 0.2658 -0.0158
B6.PWD-Chr10.1 m 0.1 0.0641 0.2259 -0.0259
B6.PWD-Chr10.2 f 0.0 0.0641 0.1259 -0.1259
B6.PWD-Chr10.2 m 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr10.3 f 0.0 0.0766 0.1505 -0.1505
B6.PWD-Chr10.3 m 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr11.1 f 0.125 0.0716 0.2658 -0.0158
B6.PWD-Chr11.1 m 0.125 0.0716 0.2658 -0.0158
B6.PWD-Chr11.2 f 0.0 0.0766 0.1505 -0.1505
B6.PWD-Chr11.2 m 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr11.3 f 0.2857 0.0766 0.4362 0.1352
B6.PWD-Chr11.3 m 0.1111 0.0675 0.2439 -0.0216
B6.PWD-Chr12 f 0.1111 0.0675 0.2439 -0.0216
B6.PWD-Chr12 m 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr13 f 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr13 m 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr14 f 0.0 0.0675 0.1327 -0.1327
B6.PWD-Chr14 m 0.0 0.0675 0.1327 -0.1327
B6.PWD-Chr15 f 0.1111 0.0675 0.2439 -0.0216
B6.PWD-Chr15 m 0.125 0.0716 0.2658 -0.0158
B6.PWD-Chr16 f 0.0 0.0611 0.1201 -0.1201
B6.PWD-Chr16 m 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr17 f 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr17 m 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr18 f 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr18 m 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr19 f 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr19 m 0.0 0.0675 0.1327 -0.1327
B6.PWD-Chr2 f 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr2 m 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr3 f 0.25 0.0716 0.3908 0.1092
B6.PWD-Chr3 m 0.1111 0.0675 0.2439 -0.0216
B6.PWD-Chr5 f 0.0 0.0641 0.1259 -0.1259
B6.PWD-Chr5 m 0.0 0.0716 0.1408 -0.1408
B6.PWD-Chr6 f 0.1111 0.0675 0.2439 -0.0216
B6.PWD-Chr6 m 0.1429 0.0766 0.2934 -0.0077
B6.PWD-Chr8 f 0.0 0.0611 0.1201 -0.1201
B6.PWD-Chr8 m 0.1 0.0641 0.2259 -0.0259
B6.PWD-Chr9 f 0.0 0.0611 0.1201 -0.1201
B6.PWD-Chr9 m 0.0 0.0716 0.1408 -0.1408
B6.PWD-ChrX.1 f 0.0 0.0716 0.1408 -0.1408
B6.PWD-ChrX.1 m 0.0 0.0716 0.1408 -0.1408
B6.PWD-ChrX.2 f 0.0 0.0641 0.1259 -0.1259
B6.PWD-ChrX.2 m 0.0 0.0641 0.1259 -0.1259
B6.PWD-ChrX.3 f 0.0 0.0675 0.1327 -0.1327
B6.PWD-ChrX.3 m 0.0 0.0716 0.1408 -0.1408
B6.PWD-ChrY f 0.0 0.0716 0.1408 -0.1408
B6.PWD-ChrY m 0.0 0.0716 0.1408 -0.1408
B6.PWD-mt f 0.0 0.0675 0.1327 -0.1327
B6.PWD-mt m 0.0 0.0716 0.1408 -0.1408
C57BL/6J f 0.0 0.0675 0.1327 -0.1327
C57BL/6J m 0.0 0.0675 0.1327 -0.1327
PWD/PhJ f 0.0 0.0611 0.1201 -0.1201
PWD/PhJ m 0.0 0.0766 0.1505 -0.1505


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 0.3542 0.0492 0.4509 0.2574
B6.PWD-Chr10.1 both 0.1125 0.0481 0.207 0.018
B6.PWD-Chr10.2 both 0.0 0.0481 0.0945 -0.0945
B6.PWD-Chr10.3 both 0.0 0.0524 0.1031 -0.1031
B6.PWD-Chr11.1 both 0.125 0.0507 0.2246 0.0254
B6.PWD-Chr11.2 both 0.0 0.0524 0.1031 -0.1031
B6.PWD-Chr11.3 both 0.1984 0.0511 0.2988 0.0981
B6.PWD-Chr12 both 0.0556 0.0492 0.1523 -0.0412
B6.PWD-Chr13 both 0.0 0.0507 0.0996 -0.0996
B6.PWD-Chr14 both 0.0 0.0478 0.0939 -0.0939
B6.PWD-Chr15 both 0.1181 0.0492 0.2148 0.0213
B6.PWD-Chr16 both 0.0 0.0471 0.0925 -0.0925
B6.PWD-Chr17 both 0.0 0.0507 0.0996 -0.0996
B6.PWD-Chr18 both 0.0 0.0507 0.0996 -0.0996
B6.PWD-Chr19 both 0.0 0.0492 0.0968 -0.0968
B6.PWD-Chr2 both 0.0 0.0507 0.0996 -0.0996
B6.PWD-Chr3 both 0.1806 0.0492 0.2773 0.0838
B6.PWD-Chr5 both 0.0 0.0481 0.0945 -0.0945
B6.PWD-Chr6 both 0.127 0.0511 0.2273 0.0266
B6.PWD-Chr8 both 0.05 0.0443 0.137 -0.037
B6.PWD-Chr9 both 0.0 0.0471 0.0925 -0.0925
B6.PWD-ChrX.1 both 0.0 0.0507 0.0996 -0.0996
B6.PWD-ChrX.2 both 0.0 0.0453 0.089 -0.089
B6.PWD-ChrX.3 both 0.0 0.0492 0.0968 -0.0968
B6.PWD-ChrY both 0.0 0.0507 0.0996 -0.0996
B6.PWD-mt both 0.0 0.0492 0.0968 -0.0968
C57BL/6J both 0.0 0.0478 0.0939 -0.0939
PWD/PhJ both 0.0 0.049 0.0963 -0.0963




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA