Project measure / variable:   Donahue9   BUN

ID, description, units MPD:41817   BUN   blood urea nitrogen (serum BUN)   [mg/dL]  
Data set, strains Donahue9   B6.PWD consomic w/par   25 strains     sex: both     age: 11wks
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  STRAIN COMPARISON PLOT
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Donahue9 - blood urea nitrogen (serum BUN)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains25 strains
Mean of the strain means25.5   mg/dL 29.3   mg/dL
Median of the strain means26.2   mg/dL 29.5   mg/dL
SD of the strain means± 2.94 ± 3.45
Coefficient of variation (CV)0.115 0.118
Min–max range of strain means18.6   –   30.6   mg/dL 22.0   –   35.8   mg/dL
Mean sample size per strain8.2   mice 8.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1603.6348 1603.6348 113.5883 < 0.0001
strain 22 2752.5639 125.1165 8.8622 < 0.0001
sex:strain 22 544.4513 24.7478 1.7529 0.0205
Residuals 331 4673.0423 14.118


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 27.6 3.29   8 1.16 0.119 24.0, 34.0 0.71
B6.PWD-Chr1 m 27.8 2.55   8 0.901 0.0919 24.0, 32.0 -0.44
B6.PWD-Chr10.1 f 21.5 1.85   8 0.655 0.0861 18.0, 24.0 -1.36
B6.PWD-Chr10.1 m 29.5 8.32   8 2.94 0.282 20.0, 44.0 0.05
B6.PWD-Chr10.2 f 21.4 2.58   11 0.778 0.121 17.0, 25.0 -1.4
B6.PWD-Chr10.2 m 27.1 1.85   10 0.586 0.0684 24.0, 30.0 -0.64
B6.PWD-Chr10.3 f 28.4 2.33   8 0.822 0.082 24.0, 31.0 0.98
B6.PWD-Chr10.3 m 31.5 4.41   8 1.56 0.14 26.0, 40.0 0.63
B6.PWD-Chr11.1 f 25.4 3.6   12 1.04 0.142 20.0, 32.0 -0.04
B6.PWD-Chr11.1 m 30.6 3.73   12 1.08 0.122 26.0, 37.0 0.37
B6.PWD-Chr11.2 f 25.3 5.21   10 1.65 0.206 18.0, 34.0 -0.07
B6.PWD-Chr11.2 m 29.6 3.2   10 1.01 0.108 24.0, 34.0 0.08
B6.PWD-Chr11.3 f 27.6 1.84   10 0.581 0.0666 25.0, 30.0 0.71
B6.PWD-Chr11.3 m 28.4 2.77   8 0.981 0.0978 24.0, 32.0 -0.27
B6.PWD-Chr12 f 26.4 1.72   7 0.649 0.065 25.0, 30.0 0.3
B6.PWD-Chr12 m 33.9 7.97   8 2.82 0.235 24.0, 48.0 1.33
B6.PWD-Chr14 f 26.3 3.35   9 1.12 0.127 22.0, 33.0 0.27
B6.PWD-Chr14 m 30.4 4.28   9 1.43 0.14 26.0, 40.0 0.31
B6.PWD-Chr15 f 21.5 3.07   8 1.09 0.143 17.0, 27.0 -1.36
B6.PWD-Chr15 m 24.1 3.27   8 1.16 0.136 20.0, 30.0 -1.51
B6.PWD-Chr16 f 25.3 2.87   10 0.907 0.113 21.0, 30.0 -0.07
B6.PWD-Chr16 m 33.3 3.5   6 1.43 0.105 29.0, 38.0 1.16
B6.PWD-Chr17 f 22.0 2.62   8 0.926 0.119 19.0, 25.0 -1.19
B6.PWD-Chr17 m 27.5 3.12   8 1.1 0.113 24.0, 34.0 -0.53
B6.PWD-Chr18 f 26.4 1.92   8 0.68 0.0729 23.0, 29.0 0.3
B6.PWD-Chr18 m 32.0 1.69   8 0.598 0.0528 29.0, 35.0 0.78
B6.PWD-Chr19 f 26.2 2.19   8 0.773 0.0833 23.0, 29.0 0.24
B6.PWD-Chr19 m 27.2 4.4   8 1.56 0.161 21.0, 34.0 -0.61
B6.PWD-Chr3 m 22.0 2.0   9 0.667 0.0909 20.0, 26.0 -2.12
B6.PWD-Chr5 f 30.6 4.0   8 1.41 0.131 25.0, 37.0 1.73
B6.PWD-Chr5 m 32.8 4.56   8 1.61 0.139 28.0, 42.0 1.01
B6.PWD-Chr6 f 18.6 4.34   8 1.53 0.233 14.0, 27.0 -2.35
B6.PWD-Chr6 m 23.4 3.25   8 1.15 0.139 19.0, 28.0 -1.72
B6.PWD-Chr9 f 27.5 2.08   4 1.04 0.0757 25.0, 30.0 0.68
B6.PWD-Chr9 m 24.6 2.82   7 1.07 0.115 21.0, 28.0 -1.37
B6.PWD-ChrX.1 f 28.4 5.98   5 2.68 0.211 21.0, 34.0 0.98
B6.PWD-ChrX.1 m 33.7 3.93   6 1.61 0.117 29.0, 39.0 1.27
B6.PWD-ChrX.2 m 30.3 2.92   9 0.972 0.0961 26.0, 34.0 0.29
B6.PWD-ChrX.3 f 27.6 2.2   8 0.778 0.0796 24.0, 30.0 0.71
B6.PWD-ChrX.3 m 31.1 6.1   8 2.16 0.196 23.0, 43.0 0.52
B6.PWD-ChrY f 25.5 3.42   8 1.21 0.134 21.0, 33.0 0.0
B6.PWD-ChrY m 29.0 2.93   8 1.04 0.101 26.0, 35.0 -0.09
B6.PWD-mt f 29.2 4.23   8 1.5 0.145 23.0, 36.0 1.26
B6.PWD-mt m 35.8 4.71   8 1.67 0.132 30.0, 43.0 1.88
C57BL/6J f 23.7 1.6   7 0.606 0.0676 21.0, 26.0 -0.62
C57BL/6J m 29.4 3.29   8 1.16 0.112 24.0, 34.0 0.02
PWD/PhJ f 24.3 3.99   7 1.51 0.164 21.0, 30.0 -0.41
PWD/PhJ m 27.9 3.55   9 1.18 0.127 21.0, 33.0 -0.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 27.625 1.3284 30.2382 25.0118
B6.PWD-Chr1 m 27.75 1.3284 30.3632 25.1368
B6.PWD-Chr10.1 f 21.5 1.3284 24.1132 18.8868
B6.PWD-Chr10.1 m 29.5 1.3284 32.1132 26.8868
B6.PWD-Chr10.2 f 21.3636 1.1329 23.5922 19.1351
B6.PWD-Chr10.2 m 27.1 1.1882 29.4374 24.7626
B6.PWD-Chr10.3 f 28.375 1.3284 30.9882 25.7618
B6.PWD-Chr10.3 m 31.5 1.3284 34.1132 28.8868
B6.PWD-Chr11.1 f 25.4167 1.0847 27.5504 23.283
B6.PWD-Chr11.1 m 30.5833 1.0847 32.717 28.4496
B6.PWD-Chr11.2 f 25.3 1.1882 27.6374 22.9626
B6.PWD-Chr11.2 m 29.6 1.1882 31.9374 27.2626
B6.PWD-Chr11.3 f 27.6 1.1882 29.9374 25.2626
B6.PWD-Chr11.3 m 28.375 1.3284 30.9882 25.7618
B6.PWD-Chr12 f 26.4286 1.4202 29.2222 23.6349
B6.PWD-Chr12 m 33.875 1.3284 36.4882 31.2618
B6.PWD-Chr14 f 26.3333 1.2525 28.7971 23.8695
B6.PWD-Chr14 m 30.4444 1.2525 32.9082 27.9807
B6.PWD-Chr15 f 21.5 1.3284 24.1132 18.8868
B6.PWD-Chr15 m 24.125 1.3284 26.7382 21.5118
B6.PWD-Chr16 f 25.3 1.1882 27.6374 22.9626
B6.PWD-Chr16 m 33.3333 1.5339 36.3508 30.3158
B6.PWD-Chr17 f 22.0 1.3284 24.6132 19.3868
B6.PWD-Chr17 m 27.5 1.3284 30.1132 24.8868
B6.PWD-Chr18 f 26.375 1.3284 28.9882 23.7618
B6.PWD-Chr18 m 32.0 1.3284 34.6132 29.3868
B6.PWD-Chr19 f 26.25 1.3284 28.8632 23.6368
B6.PWD-Chr19 m 27.25 1.3284 29.8632 24.6368
B6.PWD-Chr5 f 30.625 1.3284 33.2382 28.0118
B6.PWD-Chr5 m 32.75 1.3284 35.3632 30.1368
B6.PWD-Chr6 f 18.625 1.3284 21.2382 16.0118
B6.PWD-Chr6 m 23.375 1.3284 25.9882 20.7618
B6.PWD-Chr9 f 27.5 1.8787 31.1957 23.8043
B6.PWD-Chr9 m 24.5714 1.4202 27.3651 21.7778
B6.PWD-ChrX.1 f 28.4 1.6804 31.7055 25.0945
B6.PWD-ChrX.1 m 33.6667 1.5339 36.6842 30.6492
B6.PWD-ChrX.3 f 27.625 1.3284 30.2382 25.0118
B6.PWD-ChrX.3 m 31.125 1.3284 33.7382 28.5118
B6.PWD-ChrY f 25.5 1.3284 28.1132 22.8868
B6.PWD-ChrY m 29.0 1.3284 31.6132 26.3868
B6.PWD-mt f 29.25 1.3284 31.8632 26.6368
B6.PWD-mt m 35.75 1.3284 38.3632 33.1368
C57BL/6J f 23.7143 1.4202 26.508 20.9206
C57BL/6J m 29.375 1.3284 31.9882 26.7618
PWD/PhJ f 24.2857 1.4202 27.0794 21.492
PWD/PhJ m 27.8889 1.2525 30.3527 25.4251


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 27.6875 0.9393 29.5353 25.8397
B6.PWD-Chr10.1 both 25.5 0.9393 27.3478 23.6522
B6.PWD-Chr10.2 both 24.2318 0.8209 25.8466 22.6171
B6.PWD-Chr10.3 both 29.9375 0.9393 31.7853 28.0897
B6.PWD-Chr11.1 both 28.0 0.767 29.5088 26.4912
B6.PWD-Chr11.2 both 27.45 0.8402 29.1028 25.7972
B6.PWD-Chr11.3 both 27.9875 0.8911 29.7405 26.2345
B6.PWD-Chr12 both 30.1518 0.9723 32.0645 28.2391
B6.PWD-Chr14 both 28.3889 0.8856 30.1311 26.6467
B6.PWD-Chr15 both 22.8125 0.9393 24.6603 20.9647
B6.PWD-Chr16 both 29.3167 0.9702 31.2251 27.4082
B6.PWD-Chr17 both 24.75 0.9393 26.5978 22.9022
B6.PWD-Chr18 both 29.1875 0.9393 31.0353 27.3397
B6.PWD-Chr19 both 26.75 0.9393 28.5978 24.9022
B6.PWD-Chr5 both 31.6875 0.9393 33.5353 29.8397
B6.PWD-Chr6 both 21.0 0.9393 22.8478 19.1522
B6.PWD-Chr9 both 26.0357 1.1775 28.3521 23.7193
B6.PWD-ChrX.1 both 31.0333 1.1376 33.2712 28.7955
B6.PWD-ChrX.3 both 29.375 0.9393 31.2228 27.5272
B6.PWD-ChrY both 27.25 0.9393 29.0978 25.4022
B6.PWD-mt both 32.5 0.9393 34.3478 30.6522
C57BL/6J both 26.5446 0.9723 28.4573 24.6319
PWD/PhJ both 26.0873 0.9468 27.9498 24.2249




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA