Project measure / variable:   Donahue9   carbon_dioxide

ID, description, units MPD:41813   carbon_dioxide   dissolved-ionized carbon dioxide (serum CO2)   [mmol/L]  
Data set, strains Donahue9   B6.PWD consomic w/par   24 strains     sex: both     age: 11wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Donahue9 - dissolved-ionized carbon dioxide (serum CO2)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains24 strains
Mean of the strain means11.8   mmol/L 11.5   mmol/L
Median of the strain means12.1   mmol/L 12.0   mmol/L
SD of the strain means± 2.63 ± 3.33
Coefficient of variation (CV)0.223 0.290
Min–max range of strain means4.70   –   15.6   mmol/L 2.55   –   15.3   mmol/L
Mean sample size per strain5.7   mice 6.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 6.3962 6.3962 0.9409 0.3331
strain 21 1162.8719 55.3749 8.1461 < 0.0001
sex:strain 21 558.4914 26.5948 3.9123 < 0.0001
Residuals 225 1529.4883 6.7977


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 14.7 3.12   8 1.1 0.213 10.9, 19.8 1.1
B6.PWD-Chr1 m 14.4 2.1   8 0.744 0.146 11.3, 16.9 0.88
B6.PWD-Chr10.1 f 12.6 1.77   4 0.884 0.14 10.6, 14.9 0.3
B6.PWD-Chr10.1 m 11.5 2.59   8 0.917 0.224 7.8, 14.3 0.01
B6.PWD-Chr10.2 f 10.4 1.56   5 0.697 0.15 8.6, 12.6 -0.53
B6.PWD-Chr10.2 m 9.04 2.4   10 0.758 0.265 5.6, 12.6 -0.73
B6.PWD-Chr10.3 f 7.15 2.42   6 0.99 0.339 4.2, 11.1 -1.77
B6.PWD-Chr10.3 m 15.2 2.7   6 1.1 0.177 12.3, 19.6 1.12
B6.PWD-Chr11.1 f 12.6 0.85   7 0.321 0.0676 11.7, 14.2 0.3
B6.PWD-Chr11.1 m 12.2 1.63   12 0.471 0.134 10.1, 14.6 0.22
B6.PWD-Chr11.2 f 13.1 5.27   8 1.86 0.404 4.5, 20.4 0.49
B6.PWD-Chr11.2 m 14.7 0.88   9 0.293 0.0599 13.4, 16.5 0.97
B6.PWD-Chr11.3 f 12.1 1.42   10 0.45 0.117 10.7, 15.0 0.11
B6.PWD-Chr11.3 m 12.1 2.37   8 0.839 0.196 8.3, 15.2 0.19
B6.PWD-Chr12 f 4.7 0.707   2   0.5 0.15 4.2, 5.2 -2.7
B6.PWD-Chr12 m 3.9 1.65   3 0.954 0.424 2.8, 5.8 -2.27
B6.PWD-Chr14 f 11.6 3.52   7 1.33 0.305 7.7, 18.2 -0.08
B6.PWD-Chr14 m 8.77 2.27   7 0.856 0.258 6.0, 11.4 -0.81
B6.PWD-Chr15 f 14.2 1.52   5 0.678 0.107 12.0, 15.8 0.91
B6.PWD-Chr15 m 11.7 2.0   3 1.16 0.171 10.2, 14.0 0.07
B6.PWD-Chr16 f 13.8 0.662   6 0.27 0.0481 13.2, 15.0 0.76
B6.PWD-Chr16 m 2.55 1.63   2   1.15 0.638 1.4, 3.7 -2.68
B6.PWD-Chr17 f 13.8 1.37   7 0.517 0.0994 12.8, 16.8 0.76
B6.PWD-Chr17 m 15.3 3.13   8 1.11 0.205 9.8, 18.6 1.15
B6.PWD-Chr18 f 15.6 1.78   7 0.672 0.114 13.0, 17.4 1.44
B6.PWD-Chr18 m 14.4 1.53   7 0.576 0.106 12.2, 16.6 0.88
B6.PWD-Chr19 f 11.7 3.04   4 1.52 0.261 7.4, 14.6 -0.04
B6.PWD-Chr19 m 12.1 1.92   6 0.783 0.158 10.2, 15.4 0.19
B6.PWD-Chr3 m 14.0 2.28   7 0.864 0.163 10.2, 17.4 0.76
B6.PWD-Chr5 f 12.0 1.53   7 0.577 0.127 9.0, 13.5 0.08
B6.PWD-Chr5 m 14.3 2.14   8 0.756 0.149 11.5, 16.9 0.85
B6.PWD-Chr6 f 15.2 2.53   8 0.894 0.166 11.7, 18.4 1.29
B6.PWD-Chr6 m 13.4 1.79   8 0.633 0.133 11.6, 17.1 0.58
B6.PWD-ChrX.1 f 10.8 2.7   4 1.35 0.25 8.3, 13.9 -0.38
B6.PWD-ChrX.1 m 14.1 6.11   3 3.53 0.434 7.4, 19.4 0.79
B6.PWD-ChrX.2 m 11.9 6.38   6 2.6 0.536 1.8, 21.4 0.13
B6.PWD-ChrX.3 f 12.1 1.12   3 0.644 0.0924 10.8, 12.9 0.11
B6.PWD-ChrX.3 m 7.75 4.91   6 2.0 0.633 2.1, 15.0 -1.12
B6.PWD-ChrY f 10.3 4.59   6 1.88 0.447 5.5, 17.7 -0.57
B6.PWD-ChrY m 10.5 5.45   6 2.23 0.522 4.4, 17.8 -0.29
B6.PWD-mt f 9.05 1.38   4 0.689 0.152 7.4, 10.5 -1.04
B6.PWD-mt m 8.7 1.14   3 0.656 0.131 7.4, 9.5 -0.83
C57BL/6J f 13.1 1.58   5 0.706 0.121 11.5, 15.2 0.49
C57BL/6J m 11.7 2.86   7 1.08 0.244 7.3, 14.2 0.07
PWD/PhJ f 9.03 1.4   3 0.809 0.155 7.9, 10.6 -1.05
PWD/PhJ m 11.3 1.09   5 0.488 0.097 9.5, 12.4 -0.05


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 14.65 0.9218 16.4665 12.8335
B6.PWD-Chr1 m 14.4375 0.9218 16.254 12.621
B6.PWD-Chr10.1 f 12.625 1.3036 15.1939 10.0561
B6.PWD-Chr10.1 m 11.55 0.9218 13.3665 9.7335
B6.PWD-Chr10.2 f 10.36 1.166 12.6577 8.0623
B6.PWD-Chr10.2 m 9.04 0.8245 10.6647 7.4153
B6.PWD-Chr10.3 f 7.15 1.0644 9.2475 5.0525
B6.PWD-Chr10.3 m 15.2 1.0644 17.2975 13.1025
B6.PWD-Chr11.1 f 12.5714 0.9854 14.5133 10.6295
B6.PWD-Chr11.1 m 12.1917 0.7526 13.6748 10.7085
B6.PWD-Chr11.2 f 13.05 0.9218 14.8665 11.2335
B6.PWD-Chr11.2 m 14.7 0.8691 16.4126 12.9874
B6.PWD-Chr11.3 f 12.11 0.8245 13.7347 10.4853
B6.PWD-Chr11.3 m 12.0875 0.9218 13.904 10.271
B6.PWD-Chr12 f 4.7 1.8436 8.3329 1.0671
B6.PWD-Chr12 m 3.9 1.5053 6.8663 0.9337
B6.PWD-Chr14 f 11.5571 0.9854 13.499 9.6153
B6.PWD-Chr14 m 8.7714 0.9854 10.7133 6.8295
B6.PWD-Chr15 f 14.2 1.166 16.4977 11.9023
B6.PWD-Chr15 m 11.7333 1.5053 14.6996 8.7671
B6.PWD-Chr16 f 13.7667 1.0644 15.8641 11.6692
B6.PWD-Chr16 m 2.55 1.8436 6.1829 0.0
B6.PWD-Chr17 f 13.7714 0.9854 15.7133 11.8295
B6.PWD-Chr17 m 15.275 0.9218 17.0915 13.4585
B6.PWD-Chr18 f 15.5714 0.9854 17.5133 13.6295
B6.PWD-Chr18 m 14.4286 0.9854 16.3705 12.4867
B6.PWD-Chr19 f 11.65 1.3036 14.2189 9.0811
B6.PWD-Chr19 m 12.1 1.0644 14.1975 10.0025
B6.PWD-Chr5 f 12.0143 0.9854 13.9562 10.0724
B6.PWD-Chr5 m 14.3125 0.9218 16.129 12.496
B6.PWD-Chr6 f 15.2375 0.9218 17.054 13.421
B6.PWD-Chr6 m 13.45 0.9218 15.2665 11.6335
B6.PWD-ChrX.1 f 10.8 1.3036 13.3689 8.2311
B6.PWD-ChrX.1 m 14.0667 1.5053 17.0329 11.1004
B6.PWD-ChrX.3 f 12.0667 1.5053 15.0329 9.1004
B6.PWD-ChrX.3 m 7.75 1.0644 9.8475 5.6525
B6.PWD-ChrY f 10.2833 1.0644 12.3808 8.1859
B6.PWD-ChrY m 10.45 1.0644 12.5475 8.3525
B6.PWD-mt f 9.05 1.3036 11.6189 6.4811
B6.PWD-mt m 8.7 1.5053 11.6663 5.7337
C57BL/6J f 13.06 1.166 15.3577 10.7623
C57BL/6J m 11.7429 0.9854 13.6847 9.801
PWD/PhJ f 9.0333 1.5053 11.9996 6.0671
PWD/PhJ m 11.26 1.166 13.5577 8.9623


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 14.5438 0.6518 15.8282 13.2593
B6.PWD-Chr10.1 both 12.0875 0.7983 13.6606 10.5144
B6.PWD-Chr10.2 both 9.7 0.714 11.107 8.293
B6.PWD-Chr10.3 both 11.175 0.7526 12.6581 9.6919
B6.PWD-Chr11.1 both 12.3815 0.62 13.6033 11.1598
B6.PWD-Chr11.2 both 13.875 0.6334 15.1232 12.6268
B6.PWD-Chr11.3 both 12.0988 0.6184 13.3173 10.8802
B6.PWD-Chr12 both 4.3 1.19 6.645 1.955
B6.PWD-Chr14 both 10.1643 0.6968 11.5374 8.7912
B6.PWD-Chr15 both 12.9667 0.952 14.8427 11.0906
B6.PWD-Chr16 both 8.1583 1.0644 10.2558 6.0609
B6.PWD-Chr17 both 14.5232 0.6747 15.8527 13.1937
B6.PWD-Chr18 both 15.0 0.6968 16.3731 13.6269
B6.PWD-Chr19 both 11.875 0.8415 13.5332 10.2168
B6.PWD-Chr5 both 13.1634 0.6747 14.4929 11.8339
B6.PWD-Chr6 both 14.3438 0.6518 15.6282 13.0593
B6.PWD-ChrX.1 both 12.4333 0.9957 14.3953 10.4713
B6.PWD-ChrX.3 both 9.9083 0.9218 11.7248 8.0919
B6.PWD-ChrY both 10.3667 0.7526 11.8498 8.8835
B6.PWD-mt both 8.875 0.9957 10.837 6.913
C57BL/6J both 12.4014 0.7633 13.9056 10.8973
PWD/PhJ both 10.1467 0.952 12.0227 8.2706




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA