Project measure / variable:   Donahue9   sodium

ID, description, units MPD:41807   sodium   sodium (serum Na)   [mmol/L]  
Data set, strains Donahue9   B6.PWD consomic w/par   24 strains     sex: both     age: 11wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Donahue9 - sodium (serum Na)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains24 strains
Mean of the strain means148   mmol/L 148   mmol/L
Median of the strain means147   mmol/L 146   mmol/L
SD of the strain means± 7.30 ± 7.22
Coefficient of variation (CV)0.0495 0.0488
Min–max range of strain means136   –   159   mmol/L 137   –   161   mmol/L
Mean sample size per strain5.7   mice 6.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 160.6245 160.6245 6.4764 0.0116
strain 21 12122.5517 577.2644 23.2753 < 0.0001
sex:strain 21 994.2353 47.3445 1.9089 0.0114
Residuals 229 5679.5598 24.8016


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 144.0 9.44   8 3.34 0.0654 131.0, 156.0 -0.49
B6.PWD-Chr1 m 145.0 6.59   8 2.33 0.0453 136.0, 155.0 -0.42
B6.PWD-Chr10.1 f 156.0 4.6   4 2.3 0.0295 152.0, 162.0 1.16
B6.PWD-Chr10.1 m 161.0 2.43   8 0.86 0.0151 156.0, 164.0 1.8
B6.PWD-Chr10.2 f 159.0 4.26   5 1.91 0.0268 157.0, 167.0 1.57
B6.PWD-Chr10.2 m 159.0 1.91   10 0.604 0.012 156.0, 162.0 1.52
B6.PWD-Chr10.3 f 158.0 1.87   6 0.764 0.0119 155.0, 160.0 1.43
B6.PWD-Chr10.3 m 153.0 1.38   6 0.565 0.00902 152.0, 156.0 0.69
B6.PWD-Chr11.1 f 154.0 1.84   7 0.696 0.012 151.0, 156.0 0.88
B6.PWD-Chr11.1 m 157.0 2.81   12 0.811 0.0179 154.0, 162.0 1.25
B6.PWD-Chr11.2 f 145.0 9.38   8 3.32 0.0645 124.0, 153.0 -0.35
B6.PWD-Chr11.2 m 152.0 4.16   9 1.39 0.0274 145.0, 157.0 0.55
B6.PWD-Chr11.3 f 156.0 3.39   10 1.07 0.0217 152.0, 161.0 1.16
B6.PWD-Chr11.3 m 156.0 2.63   8 0.931 0.0169 153.0, 160.0 1.11
B6.PWD-Chr12 f 159.0 2.55   2   1.8 0.0161 157.0, 160.0 1.57
B6.PWD-Chr12 m 152.0 6.76   6 2.76 0.0444 144.0, 161.0 0.55
B6.PWD-Chr14 f 151.0 4.64   7 1.75 0.0308 145.0, 160.0 0.47
B6.PWD-Chr14 m 154.0 4.61   7 1.74 0.0299 145.0, 158.0 0.83
B6.PWD-Chr15 f 147.0 2.5   5 1.12 0.017 145.0, 151.0 -0.07
B6.PWD-Chr15 m 149.0 1.53   3 0.882 0.0102 148.0, 151.0 0.14
B6.PWD-Chr16 f 148.0 1.39   6 0.568 0.0094 146.0, 150.0 0.06
B6.PWD-Chr16 m 156.0 8.13   2   5.75 0.052 150.0, 162.0 1.11
B6.PWD-Chr17 f 150.0 1.37   7 0.519 0.00913 149.0, 152.0 0.34
B6.PWD-Chr17 m 147.0 2.15   8 0.759 0.0146 144.0, 150.0 -0.14
B6.PWD-Chr18 f 145.0 1.41   7 0.532 0.0097 143.0, 146.0 -0.35
B6.PWD-Chr18 m 144.0 1.05   7 0.397 0.00727 143.0, 146.0 -0.55
B6.PWD-Chr19 f 143.0 4.1   4 2.05 0.0288 138.0, 147.0 -0.62
B6.PWD-Chr19 m 143.0 1.48   6 0.603 0.0104 140.0, 144.0 -0.69
B6.PWD-Chr3 m 146.0 12.1   7 4.56 0.0829 129.0, 162.0 -0.28
B6.PWD-Chr5 f 136.0 9.82   7 3.71 0.0721 119.0, 151.0 -1.58
B6.PWD-Chr5 m 139.0 11.7   8 4.14 0.0841 121.0, 158.0 -1.25
B6.PWD-Chr6 f 150.0 7.24   8 2.56 0.0483 141.0, 160.0 0.34
B6.PWD-Chr6 m 144.0 2.61   8 0.923 0.0182 139.0, 146.0 -0.55
B6.PWD-ChrX.1 f 137.0 4.51   4 2.25 0.033 132.0, 142.0 -1.44
B6.PWD-ChrX.1 m 139.0 7.58   3 4.38 0.0545 130.0, 144.0 -1.25
B6.PWD-ChrX.2 m 139.0 3.19   6 1.3 0.0229 136.0, 144.0 -1.25
B6.PWD-ChrX.3 f 137.0 1.96   3 1.13 0.0143 135.0, 139.0 -1.44
B6.PWD-ChrX.3 m 138.0 3.42   7 1.29 0.0247 133.0, 142.0 -1.39
B6.PWD-ChrY f 140.0 4.95   6 2.02 0.0355 132.0, 147.0 -1.03
B6.PWD-ChrY m 143.0 2.26   6 0.924 0.0158 141.0, 147.0 -0.69
B6.PWD-mt f 139.0 2.78   4 1.39 0.02 135.0, 142.0 -1.17
B6.PWD-mt m 137.0 5.21   3 3.01 0.0381 131.0, 140.0 -1.52
C57BL/6J f 147.0 6.33   5 2.83 0.043 142.0, 158.0 -0.07
C57BL/6J m 145.0 2.77   7 1.05 0.0191 140.0, 148.0 -0.42
PWD/PhJ f 145.0 4.71   3 2.72 0.0326 142.0, 150.0 -0.35
PWD/PhJ m 154.0 4.91   5 2.2 0.0318 149.0, 161.0 0.83


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 144.4125 1.7607 147.8818 140.9432
B6.PWD-Chr1 m 145.475 1.7607 148.9443 142.0057
B6.PWD-Chr10.1 f 155.875 2.4901 160.7814 150.9686
B6.PWD-Chr10.1 m 160.775 1.7607 164.2443 157.3057
B6.PWD-Chr10.2 f 159.3 2.2272 163.6884 154.9116
B6.PWD-Chr10.2 m 158.96 1.5749 162.0631 155.8569
B6.PWD-Chr10.3 f 157.9 2.0331 161.906 153.894
B6.PWD-Chr10.3 m 153.4 2.0331 157.406 149.394
B6.PWD-Chr11.1 f 153.5429 1.8823 157.2517 149.834
B6.PWD-Chr11.1 m 157.425 1.4376 160.2577 154.5923
B6.PWD-Chr11.2 f 145.4625 1.7607 148.9318 141.9932
B6.PWD-Chr11.2 m 151.9111 1.66 155.182 148.6402
B6.PWD-Chr11.3 f 156.37 1.5749 159.4731 153.2669
B6.PWD-Chr11.3 m 155.9625 1.7607 159.4318 152.4932
B6.PWD-Chr12 f 158.6 3.5215 165.5386 151.6614
B6.PWD-Chr12 m 152.35 2.0331 156.356 148.344
B6.PWD-Chr14 f 150.7 1.8823 154.4089 146.9911
B6.PWD-Chr14 m 154.0571 1.8823 157.766 150.3483
B6.PWD-Chr15 f 147.46 2.2272 151.8484 143.0716
B6.PWD-Chr15 m 149.3667 2.8753 155.032 143.7013
B6.PWD-Chr16 f 148.1 2.0331 152.106 144.094
B6.PWD-Chr16 m 156.25 3.5215 163.1886 149.3114
B6.PWD-Chr17 f 150.4714 1.8823 154.1803 146.7626
B6.PWD-Chr17 m 147.175 1.7607 150.6443 143.7057
B6.PWD-Chr18 f 145.1571 1.8823 148.866 141.4483
B6.PWD-Chr18 m 144.4429 1.8823 148.1517 140.734
B6.PWD-Chr19 f 142.55 2.4901 147.4564 137.6436
B6.PWD-Chr19 m 142.6667 2.0331 146.6727 138.6606
B6.PWD-Chr5 f 136.0429 1.8823 139.7517 132.334
B6.PWD-Chr5 m 139.325 1.7607 142.7943 135.8557
B6.PWD-Chr6 f 149.7875 1.7607 153.2568 146.3182
B6.PWD-Chr6 m 143.6625 1.7607 147.1318 140.1932
B6.PWD-ChrX.1 f 136.55 2.4901 141.4564 131.6436
B6.PWD-ChrX.1 m 139.0333 2.8753 144.6987 133.368
B6.PWD-ChrX.3 f 137.2667 2.8753 142.932 131.6013
B6.PWD-ChrX.3 m 138.3714 1.8823 142.0803 134.6626
B6.PWD-ChrY f 139.5 2.0331 143.506 135.494
B6.PWD-ChrY m 142.9667 2.0331 146.9727 138.9606
B6.PWD-mt f 138.85 2.4901 143.7564 133.9436
B6.PWD-mt m 136.5667 2.8753 142.232 130.9013
C57BL/6J f 147.04 2.2272 151.4284 142.6516
C57BL/6J m 144.9143 1.8823 148.6231 141.2054
PWD/PhJ f 144.8 2.8753 150.4654 139.1346
PWD/PhJ m 154.34 2.2272 158.7284 149.9516


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 144.9437 1.245 147.3969 142.4906
B6.PWD-Chr10.1 both 158.325 1.5248 161.3295 155.3205
B6.PWD-Chr10.2 both 159.13 1.3639 161.8173 156.4427
B6.PWD-Chr10.3 both 155.65 1.4376 158.4827 152.8173
B6.PWD-Chr11.1 both 155.4839 1.1843 157.8174 153.1505
B6.PWD-Chr11.2 both 148.6868 1.21 151.0709 146.3027
B6.PWD-Chr11.3 both 156.1662 1.1811 158.4935 153.839
B6.PWD-Chr12 both 155.475 2.0331 159.481 151.469
B6.PWD-Chr14 both 152.3786 1.331 155.0011 149.756
B6.PWD-Chr15 both 148.4133 1.8185 151.9964 144.8302
B6.PWD-Chr16 both 152.175 2.0331 156.181 148.169
B6.PWD-Chr17 both 148.8232 1.2887 151.3625 146.2839
B6.PWD-Chr18 both 144.8 1.331 147.4226 142.1774
B6.PWD-Chr19 both 142.6083 1.6073 145.7754 139.4413
B6.PWD-Chr5 both 137.6839 1.2887 140.2232 135.1446
B6.PWD-Chr6 both 146.725 1.245 149.1782 144.2718
B6.PWD-ChrX.1 both 137.7917 1.9018 141.539 134.0444
B6.PWD-ChrX.3 both 137.819 1.7183 141.2048 134.4333
B6.PWD-ChrY both 141.2333 1.4376 144.066 138.4006
B6.PWD-mt both 137.7083 1.9018 141.4556 133.961
C57BL/6J both 145.9771 1.458 148.85 143.1043
PWD/PhJ both 149.57 1.8185 153.1531 145.9869




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA