Project measure / variable:   Donahue5   pct_NEUT

ID, description, units MPD:41401   pct_NEUT   neutrophil differential (percentage of viable WBC)   [%]  
Data set, strains Donahue5   B6.A consomic w/par   22 strains     sex: both     age: 7wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Donahue5 - neutrophil differential (percentage of viable WBC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains22 strains
Mean of the strain means10.4   % 12.1   %
Median of the strain means10.1   % 10.8   %
SD of the strain means± 3.55 ± 5.33
Coefficient of variation (CV)0.342 0.441
Min–max range of strain means5.23   –   18.8   % 5.38   –   27.8   %
Mean sample size per strain8.4   mice 8.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 223.0031 223.0031 9.3068 0.0025
strain 21 6889.9866 328.0946 13.6927 < 0.0001
sex:strain 21 746.9244 35.5678 1.4844 0.0797
Residuals 341 8170.7758 23.9612


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 15.0 10.3   16 2.57 0.688 3.07, 31.7 1.3
A/J m 14.0 8.02   16 2.01 0.572 5.12, 25.2 0.36
B6.A-Chr1 f 10.9 1.41   8 0.497 0.129 8.84, 12.5 0.15
B6.A-Chr1 m 13.1 2.09   8 0.74 0.16 10.1, 16.2 0.19
B6.A-Chr10 f 10.1 4.4   8 1.56 0.438 4.89, 18.2 -0.08
B6.A-Chr10 m 10.5 3.69   8 1.3 0.352 4.29, 15.3 -0.3
B6.A-Chr11 f 7.95 2.4   8 0.848 0.302 4.5, 11.1 -0.69
B6.A-Chr11 m 7.76 2.97   8 1.05 0.383 5.45, 14.5 -0.81
B6.A-Chr12 f 10.1 3.88   8 1.37 0.386 4.28, 15.1 -0.08
B6.A-Chr12 m 12.8 3.13   8 1.11 0.245 8.18, 16.3 0.14
B6.A-Chr13 f 7.93 5.13   8 1.81 0.647 4.32, 18.5 -0.69
B6.A-Chr13 m 9.01 3.7   8 1.31 0.41 5.34, 16.4 -0.58
B6.A-Chr14 f 11.0 4.1   8 1.45 0.374 6.78, 17.3 0.17
B6.A-Chr14 m 8.73 1.31   8 0.464 0.15 6.89, 10.5 -0.63
B6.A-Chr15 f 7.96 3.44   8 1.22 0.432 1.31, 11.9 -0.68
B6.A-Chr15 m 15.0 3.54   8 1.25 0.236 11.1, 20.3 0.55
B6.A-Chr16 f 12.1 3.9   8 1.38 0.324 5.32, 18.1 0.48
B6.A-Chr16 m 11.0 3.83   8 1.35 0.348 4.11, 16.1 -0.2
B6.A-Chr17 f 5.59 2.38   8 0.843 0.426 3.19, 10.4 -1.35
B6.A-Chr17 m 6.84 1.29   8 0.456 0.189 4.9, 8.52 -0.98
B6.A-Chr18 f 7.75 1.62   8 0.574 0.21 6.25, 11.1 -0.74
B6.A-Chr18 m 9.58 2.92   8 1.03 0.305 6.62, 14.7 -0.47
B6.A-Chr19 f 6.8 3.19   8 1.13 0.468 3.41, 12.8 -1.01
B6.A-Chr19 m 7.72 2.08   8 0.735 0.269 5.2, 10.6 -0.82
B6.A-Chr2 f 9.07 4.92   9 1.64 0.542 3.44, 18.8 -0.37
B6.A-Chr2 m 9.51 5.56   8 1.97 0.585 2.96, 16.2 -0.48
B6.A-Chr3 f 18.8 7.87   8 2.78 0.418 10.3, 33.6 2.37
B6.A-Chr3 m 27.8 9.87   8 3.49 0.355 11.7, 41.0 2.95
B6.A-Chr4 f 15.3 4.28   8 1.51 0.279 8.72, 21.6 1.39
B6.A-Chr4 m 22.8 5.56   8 1.97 0.244 12.6, 32.2 2.01
B6.A-Chr5 f 7.82 2.29   8 0.811 0.293 5.29, 12.1 -0.72
B6.A-Chr5 m 9.78 5.04   8 1.78 0.515 5.91, 21.6 -0.43
B6.A-Chr6 f 7.08 2.0   8 0.707 0.282 4.56, 9.11 -0.93
B6.A-Chr6 m 6.76 2.79   8 0.987 0.413 3.45, 11.3 -1.0
B6.A-Chr7 f 11.0 7.1   8 2.51 0.646 3.3, 23.3 0.17
B6.A-Chr7 m 11.5 5.84   8 2.07 0.509 5.41, 23.1 -0.11
B6.A-Chr8 f 15.0 3.86   8 1.36 0.257 9.68, 20.4 1.3
B6.A-Chr8 m 15.8 5.31   8 1.88 0.335 7.53, 23.8 0.7
B6.A-Chr9 f 14.1 3.92   8 1.39 0.278 7.61, 19.1 1.05
B6.A-Chr9 m 13.5 3.31   8 1.17 0.246 9.58, 18.6 0.27
B6.A-ChrX f 11.9 3.02   8 1.07 0.252 6.74, 15.0 0.43
B6.A-ChrX m 16.9 7.48   8 2.65 0.442 6.93, 31.3 0.9
C57BL/6J f 5.23 3.13   16 0.783 0.599 1.7, 11.1 -1.45
C57BL/6J m 5.38 3.65   16 0.914 0.68 1.2, 11.8 -1.26


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 14.9519 1.2238 17.3589 12.5448
A/J m 14.02 1.2238 16.4271 11.6129
B6.A-Chr1 f 10.9112 1.7307 14.3153 7.5072
B6.A-Chr1 m 13.0625 1.7307 16.4666 9.6584
B6.A-Chr10 f 10.0512 1.7307 13.4553 6.6472
B6.A-Chr10 m 10.4612 1.7307 13.8653 7.0572
B6.A-Chr11 f 7.9487 1.7307 11.3528 4.5447
B6.A-Chr11 m 7.7637 1.7307 11.1678 4.3597
B6.A-Chr12 f 10.0538 1.7307 13.4578 6.6497
B6.A-Chr12 m 12.795 1.7307 16.1991 9.3909
B6.A-Chr13 f 7.9275 1.7307 11.3316 4.5234
B6.A-Chr13 m 9.0075 1.7307 12.4116 5.6034
B6.A-Chr14 f 10.9838 1.7307 14.3878 7.5797
B6.A-Chr14 m 8.7312 1.7307 12.1353 5.3272
B6.A-Chr15 f 7.955 1.7307 11.3591 4.5509
B6.A-Chr15 m 14.9625 1.7307 18.3666 11.5584
B6.A-Chr16 f 12.0638 1.7307 15.4678 8.6597
B6.A-Chr16 m 11.005 1.7307 14.4091 7.6009
B6.A-Chr17 f 5.595 1.7307 8.9991 2.1909
B6.A-Chr17 m 6.8375 1.7307 10.2416 3.4334
B6.A-Chr18 f 7.7513 1.7307 11.1553 4.3472
B6.A-Chr18 m 9.58 1.7307 12.9841 6.1759
B6.A-Chr19 f 6.805 1.7307 10.2091 3.4009
B6.A-Chr19 m 7.7162 1.7307 11.1203 4.3122
B6.A-Chr2 f 9.0722 1.6317 12.2816 5.8628
B6.A-Chr2 m 9.505 1.7307 12.9091 6.1009
B6.A-Chr3 f 18.8125 1.7307 22.2166 15.4084
B6.A-Chr3 m 27.775 1.7307 31.1791 24.3709
B6.A-Chr4 f 15.34 1.7307 18.7441 11.9359
B6.A-Chr4 m 22.7625 1.7307 26.1666 19.3584
B6.A-Chr5 f 7.825 1.7307 11.2291 4.4209
B6.A-Chr5 m 9.775 1.7307 13.1791 6.3709
B6.A-Chr6 f 7.0837 1.7307 10.4878 3.6797
B6.A-Chr6 m 6.765 1.7307 10.1691 3.3609
B6.A-Chr7 f 10.9812 1.7307 14.3853 7.5772
B6.A-Chr7 m 11.4663 1.7307 14.8703 8.0622
B6.A-Chr8 f 15.0225 1.7307 18.4266 11.6184
B6.A-Chr8 m 15.8287 1.7307 19.2328 12.4247
B6.A-Chr9 f 14.1137 1.7307 17.5178 10.7097
B6.A-Chr9 m 13.4712 1.7307 16.8753 10.0672
B6.A-ChrX f 11.95 1.7307 15.3541 8.5459
B6.A-ChrX m 16.9162 1.7307 20.3203 13.5122
C57BL/6J f 5.2306 1.2238 7.6377 2.8236
C57BL/6J m 5.3781 1.2238 7.7852 2.9711


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 14.4859 0.8653 16.188 12.7839
B6.A-Chr1 both 11.9869 1.2238 14.3939 9.5798
B6.A-Chr10 both 10.2562 1.2238 12.6633 7.8492
B6.A-Chr11 both 7.8562 1.2238 10.2633 5.4492
B6.A-Chr12 both 11.4244 1.2238 13.8314 9.0173
B6.A-Chr13 both 8.4675 1.2238 10.8746 6.0604
B6.A-Chr14 both 9.8575 1.2238 12.2646 7.4504
B6.A-Chr15 both 11.4587 1.2238 13.8658 9.0517
B6.A-Chr16 both 11.5344 1.2238 13.9414 9.1273
B6.A-Chr17 both 6.2163 1.2238 8.6233 3.8092
B6.A-Chr18 both 8.6656 1.2238 11.0727 6.2586
B6.A-Chr19 both 7.2606 1.2238 9.6677 4.8536
B6.A-Chr2 both 9.2886 1.1893 11.6279 6.9494
B6.A-Chr3 both 23.2937 1.2238 25.7008 20.8867
B6.A-Chr4 both 19.0512 1.2238 21.4583 16.6442
B6.A-Chr5 both 8.8 1.2238 11.2071 6.3929
B6.A-Chr6 both 6.9244 1.2238 9.3314 4.5173
B6.A-Chr7 both 11.2238 1.2238 13.6308 8.8167
B6.A-Chr8 both 15.4256 1.2238 17.8327 13.0186
B6.A-Chr9 both 13.7925 1.2238 16.1996 11.3854
B6.A-ChrX both 14.4331 1.2238 16.8402 12.0261
C57BL/6J both 5.3044 0.8653 7.0064 3.6023




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA