Project measure / variable:   Bopp1   luciferase_liver

ID, description, units MPD:36407   luciferase_liver   percentage of parasites in liver relative to all organs tested   [%]  
Plasmodium berghei study
Data set, strains Bopp1   inbred   28 strains     sex: both     age: 8-12wks
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  STRAIN COMPARISON PLOT
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Bopp1 - percentage of parasites in liver relative to all organs tested



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested26 strains25 strains
Mean of the strain means30.5   % 28.9   %
Median of the strain means28.7   % 23.5   %
SD of the strain means± 12.1 ± 13.6
Coefficient of variation (CV)0.397 0.472
Min–max range of strain means15.5   –   63.3   % 7.76   –   58.4   %
Mean sample size per strain1.9   mice 1.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 6.8339 6.8339 0.0662 0.7986
strain 13 8964.2493 689.5576 6.6815 < 0.0001
sex:strain 13 1435.5012 110.4232 1.07 0.4167
Residuals 32 3302.5103 103.2034


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 40.4 0.933   2   0.66 0.0231 39.7, 41.0 0.82
129S1/SvImJ m 21.2 3.49   2   2.47 0.164 18.8, 23.7 -0.56
A/J f 18.2 0.403   2   0.285 0.0222 17.9, 18.5 -1.01
A/J m 26.5 6.38   2   4.51 0.241 22.0, 31.0 -0.17
AKR/J f 37.8 8.88   4 4.44 0.235 25.5, 45.0 0.61
AKR/J m 46.7 5.6   3 3.23 0.12 42.3, 53.0 1.31
BTBR T+ Itpr3tf/J f 15.6 3.37   2   2.38 0.215 13.2, 18.0 -1.23
BTBR T+ Itpr3tf/J m 20.4 0.53   2   0.375 0.026 20.0, 20.8 -0.62
BUB/BnJ f 24.0 2.14   2   1.52 0.0892 22.5, 25.5 -0.53
BUB/BnJ m 22.5 9.33   2   6.59 0.415 15.9, 29.1 -0.47
C3H/HeJ f 15.5 3.45   2   2.44 0.222 13.1, 18.0 -1.24
C3H/HeJ m 22.5 2.75   2   1.95 0.122 20.6, 24.4 -0.47
C57BL/6J m 37.0 2.56   2   1.81 0.0692 35.2, 38.8 0.6
C57BR/cdJ f 26.0 7.3   2   5.17 0.281 20.9, 31.2 -0.37
C57BR/cdJ m 18.2 9.35   2   6.61 0.513 11.6, 24.8 -0.78
C58/J f 42.4 11.4   2   8.09 0.27 34.3, 50.5 0.99
C58/J m 56.5 26.1   2   18.4 0.462 38.0, 74.9 2.03
CBA/J f 22.0 0.0   1   0.0 0.0 22.0, 22.0 -0.7
CBA/J m 14.0 1.03   2   0.725 0.0734 13.2, 14.7 -1.09
CZECHII/EiJ f 22.3 0.0   1   0.0 0.0 22.3, 22.3 -0.68
CZECHII/EiJ m 23.5 0.764   2   0.54 0.0325 22.9, 24.0 -0.39
DBA/2J f 20.9 5.95   3 3.43 0.284 16.0, 27.5 -0.79
DBA/2J m 7.76 0.0   1   0.0 0.0 7.76, 7.76 -1.55
I/LnJ f 31.8 7.59   2   5.37 0.239 26.4, 37.1 0.11
I/LnJ m 19.7 0.0   1   0.0 0.0 19.7, 19.7 -0.67
KK/HlJ f 42.6 18.6   2   13.1 0.437 29.4, 55.7 1.0
KK/HlJ m 26.6 4.08   2   2.89 0.153 23.8, 29.5 -0.17
LG/J f 31.4 8.28   2   5.85 0.263 25.6, 37.3 0.08
MRL/MpJ f 39.3 4.31   2   3.04 0.11 36.3, 42.4 0.73
NOD/ShiLtJ f 22.5 3.36   3 1.94 0.15 20.2, 26.4 -0.66
NOD/ShiLtJ m 14.4 0.622   2   0.44 0.0431 14.0, 14.9 -1.06
NON/ShiLtJ f 40.6 0.0   1   0.0 0.0 40.6, 40.6 0.84
NON/ShiLtJ m 42.5 6.98   2   4.93 0.164 37.6, 47.5 1.0
NZO/HlLtJ f 63.3 5.66   2   4.01 0.0894 59.3, 67.3 2.71
NZO/HlLtJ m 58.4 1.14   2   0.805 0.0195 57.6, 59.2 2.17
NZW/LacJ f 31.6 0.0   1   0.0 0.0 31.6, 31.6 0.09
NZW/LacJ m 19.3 0.0   1   0.0 0.0 19.3, 19.3 -0.7
PERA/EiJ f 19.6 0.863   2   0.61 0.0441 18.9, 20.2 -0.9
P/J f 15.8 0.474   2   0.335 0.03 15.4, 16.1 -1.21
P/J m 32.7 0.0   1   0.0 0.0 32.7, 32.7 0.28
PL/J f 23.7 4.22   2   2.98 0.178 20.8, 26.7 -0.56
PL/J m 32.6 8.32   2   5.88 0.255 26.8, 38.5 0.27
RIIIS/J m 20.1 12.7   2   8.99 0.633 11.1, 29.1 -0.64
SJL/J f 35.8 8.01   2   5.66 0.224 30.1, 41.5 0.44
SJL/J m 52.8 0.0   1   0.0 0.0 52.8, 52.8 1.76
SM/J f 21.0 1.36   2   0.965 0.0651 20.0, 21.9 -0.78
SM/J m 21.4 8.95   2   6.33 0.419 15.1, 27.7 -0.55
SWR/J f 35.8 35.6   2   25.2 0.996 10.6, 61.0 0.44
SWR/J m 25.8 4.09   2   2.9 0.159 22.9, 28.7 -0.22
WSB/EiJ f 52.3 0.0   1   0.0 0.0 52.3, 52.3 1.8
WSB/EiJ m 38.5 14.1   3 8.15 0.366 24.1, 52.3 0.71


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 40.39 7.1834 55.0222 25.7578
129S1/SvImJ m 21.245 7.1834 35.8772 6.6128
A/J f 18.195 7.1834 32.8272 3.5628
A/J m 26.5 7.1834 41.1322 11.8678
AKR/J f 37.78 5.0795 48.1265 27.4335
AKR/J m 46.7367 5.8652 58.6838 34.7895
BTBR T+ Itpr3tf/J f 15.62 7.1834 30.2522 0.9878
BTBR T+ Itpr3tf/J m 20.395 7.1834 35.0272 5.7628
BUB/BnJ f 24.025 7.1834 38.6572 9.3928
BUB/BnJ m 22.475 7.1834 37.1072 7.8428
C3H/HeJ f 15.53 7.1834 30.1622 0.8978
C3H/HeJ m 22.495 7.1834 37.1272 7.8628
C57BR/cdJ f 26.035 7.1834 40.6672 11.4028
C57BR/cdJ m 18.23 7.1834 32.8622 3.5978
C58/J f 42.355 7.1834 56.9872 27.7228
C58/J m 56.485 7.1834 71.1172 41.8528
KK/HlJ f 42.56 7.1834 57.1922 27.9278
KK/HlJ m 26.635 7.1834 41.2672 12.0028
NOD/ShiLtJ f 22.4833 5.8652 34.4305 10.5362
NOD/ShiLtJ m 14.43 7.1834 29.0622 0.0
NZO/HlLtJ f 63.335 7.1834 77.9672 48.7028
NZO/HlLtJ m 58.415 7.1834 73.0472 43.7828
PL/J f 23.735 7.1834 38.3672 9.1028
PL/J m 32.63 7.1834 47.2622 17.9978
SM/J f 20.975 7.1834 35.6072 6.3428
SM/J m 21.39 7.1834 36.0222 6.7578
SWR/J f 35.785 7.1834 50.4172 21.1528
SWR/J m 25.775 7.1834 40.4072 11.1428


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 30.8175 5.0795 41.164 20.471
A/J both 22.3475 5.0795 32.694 12.001
AKR/J both 42.2583 3.8795 50.1606 34.3561
BTBR T+ Itpr3tf/J both 18.0075 5.0795 28.354 7.661
BUB/BnJ both 23.25 5.0795 33.5965 12.9035
C3H/HeJ both 19.0125 5.0795 29.359 8.666
C57BR/cdJ both 22.1325 5.0795 32.479 11.786
C58/J both 49.42 5.0795 59.7665 39.0735
KK/HlJ both 34.5975 5.0795 44.944 24.251
NOD/ShiLtJ both 18.4567 4.6369 27.9017 9.0116
NZO/HlLtJ both 60.875 5.0795 71.2215 50.5285
PL/J both 28.1825 5.0795 38.529 17.836
SM/J both 21.1825 5.0795 31.529 10.836
SWR/J both 30.78 5.0795 41.1265 20.4335




  GWAS USING LINEAR MIXED MODELS