Project measure / variable:   Schonfeld1   TC

ID, description, units MPD:32331   TC   total cholesterol (plasma CHOL)   [mg/dL]  
Data set, strains Schonfeld1   inbred   11 strains     sex: both     age: 9-13wks
Procedure lipid profile
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  STRAIN COMPARISON PLOT
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Schonfeld1 - total cholesterol (plasma CHOL)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means91.7   mg/dL 93.0   mg/dL
Median of the strain means80.0   mg/dL 84.1   mg/dL
SD of the strain means± 31.9 ± 25.6
Coefficient of variation (CV)0.347 0.275
Min–max range of strain means63.3   –   165   mg/dL 69.9   –   153   mg/dL
Mean sample size per strain6.2   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 295.7049 295.7049 3.3943 0.0688
strain 8 61569.6813 7696.2102 88.3412 < 0.0001
sex:strain 8 10311.4338 1288.9292 14.795 < 0.0001
Residuals 87 7579.368 87.1192


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ f 99.1 9.64   10 3.05 0.0973 87.6, 116.0 0.23
129X1/SvJ m 108.0 9.84   5 4.4 0.0908 92.0, 116.0 0.59
AKR/J f 69.5 0.716   5 0.32 0.0103 69.2, 70.8 -0.7
BALB/cByJ f 86.5 17.2   10 5.44 0.199 68.8, 113.0 -0.16
BALB/cByJ m 88.4 10.1   5 4.53 0.114 81.2, 105.0 -0.18
BALB/cJ m 69.9 10.1   5 4.53 0.145 63.4, 87.2 -0.9
C3H/HeJ f 165.0 9.92   5 4.44 0.0601 148.0, 173.0 2.3
C3H/HeJ m 114.0 4.22   5 1.89 0.0369 107.0, 117.0 0.82
C57BL/6ByJ f 63.3 7.67   5 3.43 0.121 53.2, 73.2 -0.89
C57BL/6ByJ m 70.6 4.98   5 2.23 0.0706 63.6, 76.8 -0.87
C57BL/6J f 73.1 6.97   10 2.2 0.0953 62.4, 82.0 -0.59
C57BL/6J m 84.7 4.33   5 1.94 0.0511 77.6, 88.4 -0.32
DBA/1LacJ f 66.6 4.5   5 2.01 0.0676 60.8, 71.6 -0.79
DBA/1LacJ m 76.4 4.25   5 1.9 0.0557 70.4, 80.8 -0.65
NZB/BlNJ f 124.0 16.7   5 7.46 0.134 99.2, 138.0 1.01
NZB/BlNJ m 153.0 4.66   5 2.08 0.0305 146.0, 158.0 2.35
PL/J f 96.8 4.46   5 1.99 0.0461 92.4, 102.0 0.16
PL/J m 81.3 2.88   5 1.29 0.0354 78.0, 84.8 -0.46
SWR/J f 73.5 9.11   5 4.07 0.124 58.4, 82.0 -0.57
SWR/J m 83.5 6.46   5 2.89 0.0774 75.6, 93.6 -0.37


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ f 99.06 2.9516 104.9266 93.1934
129X1/SvJ m 108.4 4.1742 116.6966 100.1034
BALB/cByJ f 86.46 2.9516 92.3266 80.5934
BALB/cByJ m 88.44 4.1742 96.7366 80.1434
C3H/HeJ f 165.0 4.1742 173.2966 156.7034
C3H/HeJ m 114.4 4.1742 122.6966 106.1034
C57BL/6ByJ f 63.28 4.1742 71.5766 54.9834
C57BL/6ByJ m 70.64 4.1742 78.9366 62.3434
C57BL/6J f 73.12 2.9516 78.9866 67.2534
C57BL/6J m 84.7 4.1742 92.9966 76.4034
DBA/1LacJ f 66.64 4.1742 74.9366 58.3434
DBA/1LacJ m 76.4 4.1742 84.6966 68.1034
NZB/BlNJ f 124.24 4.1742 132.5366 115.9434
NZB/BlNJ m 152.8 4.1742 161.0966 144.5034
PL/J f 96.76 4.1742 105.0566 88.4634
PL/J m 81.28 4.1742 89.5766 72.9834
SWR/J f 73.52 4.1742 81.8166 65.2234
SWR/J m 83.5 4.1742 91.7966 75.2034


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ both 103.73 2.5562 108.8106 98.6494
BALB/cByJ both 87.45 2.5562 92.5306 82.3694
C3H/HeJ both 139.7 2.9516 145.5666 133.8334
C57BL/6ByJ both 66.96 2.9516 72.8266 61.0934
C57BL/6J both 78.91 2.5562 83.9906 73.8294
DBA/1LacJ both 71.52 2.9516 77.3866 65.6534
NZB/BlNJ both 138.52 2.9516 144.3866 132.6534
PL/J both 89.02 2.9516 94.8866 83.1534
SWR/J both 78.51 2.9516 84.3766 72.6434




  GWAS USING LINEAR MIXED MODELS