Project measure / variable:   Eumorphia6   IVRT

ID, description, units MPD:29519   IVRT   mitral valve flow isovolumetric relaxation time   [ms]  
Data set, strains Eumorphia6   inbred   4 strains     sex: both     age: 12wks
Procedure echocardiography
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  STRAIN COMPARISON PLOT
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Eumorphia6 - mitral valve flow isovolumetric relaxation time



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means24.1   ms 25.2   ms
Median of the strain means23.4   ms 23.4   ms
SD of the strain means± 2.67 ± 4.57
Coefficient of variation (CV)0.111 0.181
Min–max range of strain means21.9   –   28.0   ms 22.2   –   31.9   ms
Mean sample size per strain5.8   mice 6.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 12.4529 12.4529 0.613 0.4384
strain 3 191.8155 63.9385 3.1475 0.0357
sex:strain 3 311.0535 103.6845 5.1041 0.0045
Residuals 39 792.2503 20.3141


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 28.0 4.05   6 1.65 0.145 21.8, 33.3 1.44
129S2/SvPas m 22.2 3.32   6 1.36 0.149 16.8, 26.0 -0.66
BALB/cByJ f 23.7 5.2   6 2.12 0.22 19.3, 32.5 -0.17
BALB/cByJ m 24.3 2.84   6 1.16 0.117 20.8, 28.5 -0.2
C3HeB/FeJ f 23.0 3.02   5 1.35 0.131 20.0, 26.8 -0.43
C3HeB/FeJ m 31.9 8.57   6 3.5 0.269 24.3, 48.5 1.47
C57BL/6J f 21.9 2.25   6 0.918 0.103 20.0, 26.0 -0.84
C57BL/6J m 22.4 3.18   6 1.3 0.142 19.3, 27.5 -0.61


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 28.0 1.84 31.7218 24.2782
129S2/SvPas m 22.2333 1.84 25.9551 18.5115
BALB/cByJ f 23.6833 1.84 27.4051 19.9615
BALB/cByJ m 24.3167 1.84 28.0385 20.5949
C3HeB/FeJ f 22.96 2.0156 27.037 18.883
C3HeB/FeJ m 31.9167 1.84 35.6385 28.1949
C57BL/6J f 21.9 1.84 25.6218 18.1782
C57BL/6J m 22.4 1.84 26.1218 18.6782


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 25.1167 1.3011 27.7484 22.485
BALB/cByJ both 24.0 1.3011 26.6317 21.3683
C3HeB/FeJ both 27.4383 1.3646 30.1985 24.6782
C57BL/6J both 22.15 1.3011 24.7817 19.5183




GWAS analysis not available: SNP data is not available for enough strains (at least 4)