Project measure / variable:   Eumorphia6   wave_ratio

ID, description, units MPD:29515   wave_ratio   mitral valve outflow (E/A) wave ratio   [ratio]  
Data set, strains Eumorphia6   inbred   4 strains     sex: both     age: 12wks
Procedure echocardiography
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  STRAIN COMPARISON PLOT
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Eumorphia6 - mitral valve outflow (E/A) wave ratio



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means1.90   ratio 2.41   ratio
Median of the strain means1.91   ratio 2.16   ratio
SD of the strain means± 0.290 ± 0.667
Coefficient of variation (CV)0.153 0.277
Min–max range of strain means1.54   –   2.23   ratio 1.92   –   3.39   ratio
Mean sample size per strain5.8   mice 6.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.9268 2.9268 24.0411 < 0.0001
strain 3 2.7063 0.9021 7.4099 0.0005
sex:strain 3 6.6741 2.2247 18.2738 < 0.0001
Residuals 39 4.7479 0.1217


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 2.23 0.191   6 0.0781 0.0859 1.89, 2.44 1.15
129S2/SvPas m 2.23 0.386   6 0.158 0.173 1.74, 2.81 -0.27
BALB/cByJ f 1.99 0.776   6 0.317 0.391 1.31, 3.25 0.33
BALB/cByJ m 2.09 0.22   6 0.09 0.106 1.77, 2.46 -0.48
C3HeB/FeJ f 1.54 0.18   5 0.0806 0.117 1.32, 1.77 -1.22
C3HeB/FeJ m 3.39 0.0   6 0.0 0.0 3.39, 3.39 1.47
C57BL/6J f 1.82 0.216   6 0.0882 0.119 1.59, 2.22 -0.26
C57BL/6J m 1.92 0.199   6 0.0813 0.103 1.7, 2.24 -0.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 2.2283 0.1424 2.5165 1.9402
129S2/SvPas m 2.2317 0.1424 2.5198 1.9435
BALB/cByJ f 1.9883 0.1424 2.2765 1.7002
BALB/cByJ m 2.0883 0.1424 2.3765 1.8002
C3HeB/FeJ f 1.538 0.156 1.8536 1.2224
C3HeB/FeJ m 3.39 0.1424 3.6781 3.1019
C57BL/6J f 1.82 0.1424 2.1081 1.5319
C57BL/6J m 1.9233 0.1424 2.2115 1.6352


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 2.23 0.1007 2.4337 2.0263
BALB/cByJ both 2.0383 0.1007 2.2421 1.8346
C3HeB/FeJ both 2.464 0.1056 2.6777 2.2503
C57BL/6J both 1.8717 0.1007 2.0754 1.6679




GWAS analysis not available: SNP data is not available for enough strains (at least 4)