Project measure / variable:   Yuan3   T4_M06

ID, description, units MPD:24476   T4_M06   thyroxine (serum T4)   [µg/dL]  at age 6mo  
Data set, strains Yuan3   inbred   30 strains     sex: both     age: 26wks
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  STRAIN COMPARISON PLOT
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Yuan3 - thyroxine (serum T4) at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains25 strains
Mean of the strain means5.53   µg/dL 4.99   µg/dL
Median of the strain means5.70   µg/dL 4.67   µg/dL
SD of the strain means± 1.36 ± 1.28
Coefficient of variation (CV)0.246 0.257
Min–max range of strain means2.40   –   7.74   µg/dL 2.08   –   8.49   µg/dL
Mean sample size per strain7.9   mice 7.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 16.1571 16.1571 19.1631 < 0.0001
strain 22 508.0246 23.092 27.3883 < 0.0001
sex:strain 22 87.3079 3.9685 4.7069 < 0.0001
Residuals 323 272.3323 0.8431


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 4.83 0.776   6 0.317 0.161 3.9, 6.0 -0.52
129S1/SvImJ m 4.44 0.798   8 0.282 0.18 2.6, 5.2 -0.43
A/J f 5.68 0.87   16 0.218 0.153 4.3, 7.2 0.11
A/J m 5.59 1.02   8 0.36 0.182 4.4, 7.8 0.47
BALB/cByJ f 6.87 0.595   8 0.21 0.0865 6.0, 7.7 0.98
BALB/cByJ m 5.71 0.503   8 0.178 0.088 5.0, 6.4 0.56
BTBR T+ Itpr3tf/J f 4.97 0.359   4 0.18 0.0722 4.7, 5.5 -0.41
BTBR T+ Itpr3tf/J m 4.26 0.652   8 0.231 0.153 3.3, 5.1 -0.57
BUB/BnJ f 3.75 0.644   6 0.263 0.172 3.1, 4.7 -1.31
BUB/BnJ m 6.23 0.826   6 0.337 0.133 5.2, 7.2 0.96
C3H/HeJ f 7.7 0.576   8 0.204 0.0748 6.6, 8.3 1.59
C3H/HeJ m 8.49 1.52   7 0.575 0.179 5.8, 10.4 2.73
C57BL/10J f 6.81 1.59   8 0.563 0.234 4.8, 9.5 0.94
C57BL/10J m 6.38 0.74   8 0.262 0.116 5.3, 7.7 1.08
C57BL/6J f 6.49 1.3   8 0.459 0.2 4.0, 8.5 0.7
C57BL/6J m 5.15 0.597   4 0.299 0.116 4.5, 5.9 0.12
C57BLKS/J f 5.62 1.28   8 0.452 0.227 3.6, 7.6 0.06
C57BLKS/J m 4.67 0.645   8 0.228 0.138 3.4, 5.4 -0.25
C57BR/cdJ m 5.23 0.0957   4 0.0479 0.0183 5.1, 5.3 0.18
C57L/J f 5.72 1.03   8 0.364 0.18 4.7, 7.6 0.14
C57L/J m 5.53 1.37   8 0.484 0.248 4.6, 8.6 0.42
CAST/EiJ f 3.47 0.404   3 0.233 0.117 3.0, 3.7 -1.51
CBA/J f 7.65 1.37   6 0.56 0.179 6.1, 9.7 1.55
DBA/2J f 6.08 1.06   8 0.373 0.174 4.7, 8.0 0.4
DBA/2J m 5.77 0.988   16 0.247 0.171 4.1, 7.7 0.61
FVB/NJ f 3.5 0.523   14 0.14 0.15 2.8, 4.1 -1.49
FVB/NJ m 3.56 0.336   9 0.112 0.0945 2.8, 3.9 -1.12
KK/HlJ f 7.74 0.672   8 0.237 0.0868 6.8, 8.6 1.62
LP/J f 4.38 0.796   8 0.281 0.182 3.1, 5.6 -0.85
LP/J m 3.61 0.631   8 0.223 0.175 2.2, 4.2 -1.08
MOLF/EiJ f 4.37 0.941   7 0.356 0.215 3.1, 6.0 -0.85
MOLF/EiJ m 4.39 0.803   7 0.303 0.183 3.2, 5.8 -0.47
MRL/MpJ m 4.92 0.523   8 0.185 0.106 4.3, 6.0 -0.06
NOD.B10Sn-H2b/J f 6.09 0.556   9 0.185 0.0912 5.4, 7.1 0.41
NOD.B10Sn-H2b/J m 4.39 1.07   7 0.405 0.244 2.5, 5.6 -0.47
NON/ShiLtJ f 5.11 1.07   8 0.38 0.21 4.1, 6.6 -0.31
NON/ShiLtJ m 4.56 0.905   8 0.32 0.198 3.7, 6.0 -0.34
NZO/HlLtJ f 4.62 0.812   8 0.287 0.176 3.2, 5.5 -0.67
NZO/HlLtJ m 4.66 0.559   5 0.25 0.12 4.2, 5.6 -0.26
NZW/LacJ f 5.78 0.604   8 0.214 0.105 4.9, 6.8 0.18
P/J f 5.83 0.875   8 0.309 0.15 4.9, 7.4 0.22
P/J m 3.6 0.593   8 0.21 0.165 2.6, 4.3 -1.09
PL/J f 5.97 0.724   10 0.229 0.121 4.8, 7.0 0.32
PL/J m 7.17 1.5   9 0.501 0.21 3.9, 9.5 1.7
PWD/PhJ f 7.24 0.758   8 0.268 0.105 6.0, 8.1 1.25
PWD/PhJ m 5.5 0.9   7 0.34 0.164 3.7, 6.5 0.39
RIIIS/J f 4.76 0.856   7 0.324 0.18 4.1, 6.3 -0.57
RIIIS/J m 4.34 1.32   8 0.466 0.304 1.4, 5.9 -0.51
SJL/J f 4.94 0.886   8 0.313 0.18 3.7, 6.5 -0.43
SM/J f 6.55 1.16   8 0.41 0.177 5.0, 8.1 0.75
SM/J m 4.61 1.13   7 0.428 0.246 3.2, 6.4 -0.3
WSB/EiJ f 2.4 0.438   8 0.155 0.182 1.8, 3.0 -2.3
WSB/EiJ m 2.08 0.354   6 0.145 0.17 1.5, 2.6 -2.27


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 4.8333 0.3749 5.5708 4.0959
129S1/SvImJ m 4.4375 0.3246 5.0762 3.7988
A/J f 5.6812 0.2296 6.1329 5.2296
A/J m 5.5875 0.3246 6.2262 4.9488
BALB/cByJ f 6.875 0.3246 7.5137 6.2363
BALB/cByJ m 5.7125 0.3246 6.3512 5.0738
BTBR T+ Itpr3tf/J f 4.975 0.4591 5.8782 4.0718
BTBR T+ Itpr3tf/J m 4.2625 0.3246 4.9012 3.6238
BUB/BnJ f 3.75 0.3749 4.4875 3.0125
BUB/BnJ m 6.2333 0.3749 6.9708 5.4959
C3H/HeJ f 7.7 0.3246 8.3387 7.0613
C3H/HeJ m 8.4857 0.3471 9.1685 7.8029
C57BL/10J f 6.8125 0.3246 7.4512 6.1738
C57BL/10J m 6.375 0.3246 7.0137 5.7363
C57BL/6J f 6.4875 0.3246 7.1262 5.8488
C57BL/6J m 5.15 0.4591 6.0532 4.2468
C57BLKS/J f 5.625 0.3246 6.2637 4.9863
C57BLKS/J m 4.675 0.3246 5.3137 4.0363
C57L/J f 5.725 0.3246 6.3637 5.0863
C57L/J m 5.525 0.3246 6.1637 4.8863
DBA/2J f 6.075 0.3246 6.7137 5.4363
DBA/2J m 5.7688 0.2296 6.2204 5.3171
FVB/NJ f 3.5 0.2454 3.9828 3.0172
FVB/NJ m 3.5556 0.3061 4.1577 2.9534
LP/J f 4.375 0.3246 5.0137 3.7363
LP/J m 3.6125 0.3246 4.2512 2.9738
MOLF/EiJ f 4.3714 0.3471 5.0542 3.6887
MOLF/EiJ m 4.3857 0.3471 5.0685 3.7029
NOD.B10Sn-H2b/J f 6.0889 0.3061 6.691 5.4867
NOD.B10Sn-H2b/J m 4.3857 0.3471 5.0685 3.7029
NON/ShiLtJ f 5.1125 0.3246 5.7512 4.4738
NON/ShiLtJ m 4.5625 0.3246 5.2012 3.9238
NZO/HlLtJ f 4.625 0.3246 5.2637 3.9863
NZO/HlLtJ m 4.66 0.4106 5.4679 3.8521
P/J f 5.825 0.3246 6.4637 5.1863
P/J m 3.6 0.3246 4.2387 2.9613
PL/J f 5.97 0.2904 6.5413 5.3987
PL/J m 7.1667 0.3061 7.7688 6.5645
PWD/PhJ f 7.2375 0.3246 7.8762 6.5988
PWD/PhJ m 5.5 0.3471 6.1828 4.8172
RIIIS/J f 4.7571 0.3471 5.4399 4.0744
RIIIS/J m 4.3375 0.3246 4.9762 3.6988
SM/J f 6.55 0.3246 7.1887 5.9113
SM/J m 4.6143 0.3471 5.2971 3.9315
WSB/EiJ f 2.4 0.3246 3.0387 1.7613
WSB/EiJ m 2.0833 0.3749 2.8208 1.3459


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4.6354 0.2479 5.1232 4.1476
A/J both 5.6344 0.1988 6.0255 5.2433
BALB/cByJ both 6.2937 0.2296 6.7454 5.8421
BTBR T+ Itpr3tf/J both 4.6187 0.2811 5.1719 4.0656
BUB/BnJ both 4.9917 0.2651 5.5131 4.4702
C3H/HeJ both 8.0929 0.2376 8.5603 7.6254
C57BL/10J both 6.5937 0.2296 7.0454 6.1421
C57BL/6J both 5.8187 0.2811 6.3719 5.2656
C57BLKS/J both 5.15 0.2296 5.6016 4.6984
C57L/J both 5.625 0.2296 6.0766 5.1734
DBA/2J both 5.9219 0.1988 6.313 5.5308
FVB/NJ both 3.5278 0.1962 3.9137 3.1419
LP/J both 3.9937 0.2296 4.4454 3.5421
MOLF/EiJ both 4.3786 0.2454 4.8614 3.8958
NOD.B10Sn-H2b/J both 5.2373 0.2314 5.6925 4.7821
NON/ShiLtJ both 4.8375 0.2296 5.2891 4.3859
NZO/HlLtJ both 4.6425 0.2617 5.1574 4.1276
P/J both 4.7125 0.2296 5.1641 4.2609
PL/J both 6.5683 0.2109 6.9833 6.1533
PWD/PhJ both 6.3687 0.2376 6.8362 5.9013
RIIIS/J both 4.5473 0.2376 5.0148 4.0799
SM/J both 5.5821 0.2376 6.0496 5.1147
WSB/EiJ both 2.2417 0.2479 2.7295 1.7539




  GWAS USING LINEAR MIXED MODELS