Project measure / variable:   Eumorphia1   ALP

ID, description, units MPD:23902   ALP   alkaline phosphatase (plasma ALP)   [IU/L]  
Data set, strains Eumorphia1   inbred   4 strains     sex: both     age: 12wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Eumorphia1 - alkaline phosphatase (plasma ALP)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means154   IU/L 128   IU/L
Median of the strain means152   IU/L 134   IU/L
SD of the strain means± 24.9 ± 16.8
Coefficient of variation (CV)0.162 0.131
Min–max range of strain means125   –   185   IU/L 104   –   141   IU/L
Mean sample size per strain30.0   mice 29.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 41214.777 41214.777 37.9874 < 0.0001
strain 3 62762.2351 20920.745 19.2825 < 0.0001
sex:strain 3 7858.7014 2619.5671 2.4144 0.0674
Residuals 229 248455.6113 1084.959


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 125.0 22.2   20 4.97 0.178 76.0, 154.0 -1.15
129S2/SvPas m 104.0 26.6   19 6.09 0.254 70.0, 173.0 -1.43
BALB/cJ f 147.0 37.1   35 6.27 0.252 69.0, 212.0 -0.27
BALB/cJ m 129.0 27.6   34 4.73 0.214 82.0, 172.0 0.06
C3HeB/FeJ f 185.0 36.0   35 6.09 0.194 125.0, 310.0 1.25
C3HeB/FeJ m 141.0 27.7   35 4.69 0.197 98.0, 262.0 0.77
C57BL/6J f 158.0 44.6   30 8.15 0.283 81.0, 236.0 0.17
C57BL/6J m 138.0 30.8   29 5.71 0.223 63.0, 185.0 0.6


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 125.1 7.3653 139.6125 110.5875
129S2/SvPas m 104.4211 7.5567 119.3105 89.5316
BALB/cJ f 147.1714 5.5677 158.1418 136.201
BALB/cJ m 129.2353 5.6489 140.3658 118.1047
C3HeB/FeJ f 185.4571 5.5677 196.4275 174.4868
C3HeB/FeJ m 141.0857 5.5677 152.0561 130.1153
C57BL/6J f 157.8 6.0138 169.6494 145.9506
C57BL/6J m 138.069 6.1166 150.1209 126.017


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 114.7605 5.2762 125.1565 104.3645
BALB/cJ both 138.2034 3.9658 146.0174 130.3893
C3HeB/FeJ both 163.2714 3.9369 171.0287 155.5142
C57BL/6J both 147.9345 4.2889 156.3852 139.4838




GWAS analysis not available: SNP data is not available for enough strains (at least 4)