Project measure / variable:   Lake2   lacrimation

ID, description, units MPD:21728   lacrimation   presence of lacrimal fluid (tears) around eyes during supine restraint (score 0-1)   [score]  
Data set, strains Lake2   B6.A consomic w/par   23 strains     sex: both     age: 8wks
Procedure observation (SHIRPA)
Ontology mappings

  STRAIN COMPARISON PLOT
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Lake2 - presence of lacrimal fluid (tears) around eyes during supine restraint (score 0-1)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains23 strains
Mean of the strain means0.0217   score 0.0435   score
Median of the strain means0   score 0   score
SD of the strain means± 0.0813 ± 0.128
Coefficient of variation (CV)3.74 2.95
Min–max range of strain means0   –   0.375   score 0   –   0.500   score
Mean sample size per strain8.3   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0496 0.0496 2.2166 0.1375
strain 22 3.3651 0.153 6.8321 < 0.0001
sex:strain 22 0.7073 0.0322 1.4361 0.0945
Residuals 335 7.5 0.0224


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 0.0 0.0   16 0.0 0.0 -0.27
A/J m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-Chr1 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr1 m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-Chr10 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr10 m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-Chr11 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr11 m 0.0 0.0   10 0.0 0.0 -0.34
B6.A-Chr12 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr12 m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-Chr13 f 0.0 0.0   5 0.0 0.0 -0.27
B6.A-Chr13 m 0.0 0.0   7 0.0 0.0 -0.34
B6.A-Chr14 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr14 m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-Chr15 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr15 m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-Chr16 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr16 m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-Chr17 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr17 m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-Chr18 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr18 m 0.125 0.354   8 0.125 2.83 0.63
B6.A-Chr19 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr19 m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-Chr2 f 0.375 0.518   8 0.183 1.38 4.35
B6.A-Chr2 m 0.5 0.535   8 0.189 1.07 3.56
B6.A-Chr3 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr3 m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-Chr4 f 0.0 0.0   7 0.0 0.0 -0.27
B6.A-Chr4 m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-Chr5 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr5 m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-Chr6 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr6 m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-Chr7 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr7 m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-Chr8 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr8 m 0.375 0.518   8 0.183 1.38 2.58
B6.A-Chr9 f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-Chr9 m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-ChrX f 0.125 0.354   8 0.125 2.83 1.27
B6.A-ChrX m 0.0 0.0   8 0.0 0.0 -0.34
B6.A-ChrY f 0.0 0.0   8 0.0 0.0 -0.27
B6.A-ChrY m 0.0 0.0   8 0.0 0.0 -0.34
C57BL/6J f 0.0 0.0   16 0.0 0.0 -0.27
C57BL/6J m 0.0 0.0   8 0.0 0.0 -0.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 0.0 0.0374 0.0736 -0.0736
A/J m 0.0 0.0529 0.1041 -0.1041
B6.A-Chr1 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr1 m 0.0 0.0529 0.1041 -0.1041
B6.A-Chr10 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr10 m 0.0 0.0529 0.1041 -0.1041
B6.A-Chr11 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr11 m 0.0 0.0473 0.0931 -0.0931
B6.A-Chr12 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr12 m 0.0 0.0529 0.1041 -0.1041
B6.A-Chr13 f 0.0 0.0669 0.1316 -0.1316
B6.A-Chr13 m 0.0 0.0566 0.1112 -0.1112
B6.A-Chr14 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr14 m 0.0 0.0529 0.1041 -0.1041
B6.A-Chr15 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr15 m 0.0 0.0529 0.1041 -0.1041
B6.A-Chr16 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr16 m 0.0 0.0529 0.1041 -0.1041
B6.A-Chr17 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr17 m 0.0 0.0529 0.1041 -0.1041
B6.A-Chr18 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr18 m 0.125 0.0529 0.2291 0.0209
B6.A-Chr19 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr19 m 0.0 0.0529 0.1041 -0.1041
B6.A-Chr2 f 0.375 0.0529 0.4791 0.2709
B6.A-Chr2 m 0.5 0.0529 0.6041 0.3959
B6.A-Chr3 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr3 m 0.0 0.0529 0.1041 -0.1041
B6.A-Chr4 f 0.0 0.0566 0.1112 -0.1112
B6.A-Chr4 m 0.0 0.0529 0.1041 -0.1041
B6.A-Chr5 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr5 m 0.0 0.0529 0.1041 -0.1041
B6.A-Chr6 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr6 m 0.0 0.0529 0.1041 -0.1041
B6.A-Chr7 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr7 m 0.0 0.0529 0.1041 -0.1041
B6.A-Chr8 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr8 m 0.375 0.0529 0.4791 0.2709
B6.A-Chr9 f 0.0 0.0529 0.1041 -0.1041
B6.A-Chr9 m 0.0 0.0529 0.1041 -0.1041
B6.A-ChrX f 0.125 0.0529 0.2291 0.0209
B6.A-ChrX m 0.0 0.0529 0.1041 -0.1041
B6.A-ChrY f 0.0 0.0529 0.1041 -0.1041
B6.A-ChrY m 0.0 0.0529 0.1041 -0.1041
C57BL/6J f 0.0 0.0374 0.0736 -0.0736
C57BL/6J m 0.0 0.0529 0.1041 -0.1041


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 0.0 0.0324 0.0637 -0.0637
B6.A-Chr1 both 0.0 0.0374 0.0736 -0.0736
B6.A-Chr10 both 0.0 0.0374 0.0736 -0.0736
B6.A-Chr11 both 0.0 0.0355 0.0698 -0.0698
B6.A-Chr12 both 0.0 0.0374 0.0736 -0.0736
B6.A-Chr13 both 0.0 0.0438 0.0862 -0.0862
B6.A-Chr14 both 0.0 0.0374 0.0736 -0.0736
B6.A-Chr15 both 0.0 0.0374 0.0736 -0.0736
B6.A-Chr16 both 0.0 0.0374 0.0736 -0.0736
B6.A-Chr17 both 0.0 0.0374 0.0736 -0.0736
B6.A-Chr18 both 0.0625 0.0374 0.1361 -0.0111
B6.A-Chr19 both 0.0 0.0374 0.0736 -0.0736
B6.A-Chr2 both 0.4375 0.0374 0.5111 0.3639
B6.A-Chr3 both 0.0 0.0374 0.0736 -0.0736
B6.A-Chr4 both 0.0 0.0387 0.0762 -0.0762
B6.A-Chr5 both 0.0 0.0374 0.0736 -0.0736
B6.A-Chr6 both 0.0 0.0374 0.0736 -0.0736
B6.A-Chr7 both 0.0 0.0374 0.0736 -0.0736
B6.A-Chr8 both 0.1875 0.0374 0.2611 0.1139
B6.A-Chr9 both 0.0 0.0374 0.0736 -0.0736
B6.A-ChrX both 0.0625 0.0374 0.1361 -0.0111
B6.A-ChrY both 0.0 0.0374 0.0736 -0.0736
C57BL/6J both 0.0 0.0324 0.0637 -0.0637




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA