Project measure / variable:   Lake1   QT_Dis

ID, description, units MPD:19946   QT_Dis   difference between smallest and largest QT interval   [ms]  
Data set, strains Lake1   B6.A consomic w/par   23 strains     sex: both     age: 11wks
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  STRAIN COMPARISON PLOT
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Lake1 - difference between smallest and largest QT interval



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains23 strains
Mean of the strain means21.6   ms 19.1   ms
Median of the strain means20.9   ms 19.6   ms
SD of the strain means± 2.79 ± 3.48
Coefficient of variation (CV)0.129 0.182
Min–max range of strain means17.1   –   27.3   ms 10.2   –   25.7   ms
Mean sample size per strain8.0   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 566.192 566.192 11.053 0.001
strain 22 2499.4189 113.6099 2.2179 0.0015
sex:strain 22 1040.1932 47.2815 0.923 0.5645
Residuals 323 16545.7569 51.2253


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 27.3 9.67   8 3.42 0.354 8.5, 38.5 2.03
A/J m 25.7 10.1   8 3.57 0.393 5.0, 41.0 1.89
B6.A-Chr1 f 19.1 6.14   8 2.17 0.322 5.5, 24.0 -0.91
B6.A-Chr1 m 19.6 3.88   8 1.37 0.198 13.0, 24.0 0.13
B6.A-Chr10 f 26.7 7.89   9 2.63 0.295 19.5, 46.0 1.82
B6.A-Chr10 m 21.2 3.08   8 1.09 0.145 18.0, 26.5 0.59
B6.A-Chr11 f 21.9 3.7   8 1.31 0.169 16.5, 29.0 0.1
B6.A-Chr11 m 17.8 8.5   8 3.0 0.479 1.5, 30.0 -0.38
B6.A-Chr12 f 24.2 10.2   8 3.61 0.422 13.5, 48.0 0.92
B6.A-Chr12 m 23.3 3.27   8 1.16 0.14 19.5, 27.5 1.2
B6.A-Chr13 f 20.7 3.18   8 1.13 0.154 17.5, 27.0 -0.33
B6.A-Chr13 m 13.9 7.65   8 2.7 0.551 6.0, 28.0 -1.51
B6.A-Chr14 f 23.9 7.2   8 2.55 0.301 18.5, 40.5 0.81
B6.A-Chr14 m 17.4 3.12   8 1.1 0.179 12.5, 21.0 -0.5
B6.A-Chr15 f 19.3 9.64   9 3.21 0.5 2.5, 36.5 -0.83
B6.A-Chr15 m 16.6 5.78   7 2.18 0.349 10.0, 25.0 -0.73
B6.A-Chr16 f 20.8 5.04   8 1.78 0.242 15.0, 29.5 -0.3
B6.A-Chr16 m 18.6 4.46   8 1.58 0.24 12.0, 25.0 -0.15
B6.A-Chr17 f 25.8 6.72   8 2.38 0.261 19.0, 40.5 1.49
B6.A-Chr17 m 22.7 5.66   7 2.14 0.249 13.0, 28.5 1.02
B6.A-Chr18 f 22.2 3.29   8 1.16 0.148 19.0, 28.5 0.2
B6.A-Chr18 m 20.6 6.35   8 2.24 0.309 10.5, 27.5 0.42
B6.A-Chr19 f 20.6 7.4   8 2.62 0.36 9.0, 32.5 -0.37
B6.A-Chr19 m 19.8 6.87   8 2.43 0.347 9.0, 29.0 0.19
B6.A-Chr2 f 17.1 7.45   8 2.64 0.435 9.0, 30.5 -1.62
B6.A-Chr2 m 18.2 6.26   8 2.21 0.343 10.0, 27.5 -0.27
B6.A-Chr3 f 19.9 5.01   8 1.77 0.252 13.0, 27.5 -0.62
B6.A-Chr3 m 21.8 9.0   8 3.18 0.414 10.5, 39.5 0.76
B6.A-Chr4 f 22.6 18.4   8 6.51 0.817 6.5, 63.5 0.35
B6.A-Chr4 m 10.2 6.7   8 2.37 0.653 2.0, 23.5 -2.57
B6.A-Chr5 f 22.6 10.6   8 3.73 0.467 15.5, 48.0 0.35
B6.A-Chr5 m 15.8 4.8   8 1.7 0.304 10.5, 24.0 -0.96
B6.A-Chr6 f 19.9 2.32   7 0.878 0.117 16.0, 23.5 -0.62
B6.A-Chr6 m 20.1 6.33   8 2.24 0.316 10.5, 28.5 0.28
B6.A-Chr7 f 20.9 6.34   8 2.24 0.303 10.0, 32.0 -0.26
B6.A-Chr7 m 22.2 3.32   8 1.17 0.149 16.5, 26.0 0.88
B6.A-Chr8 f 23.3 9.67   8 3.42 0.415 12.0, 39.5 0.6
B6.A-Chr8 m 22.0 4.45   12 1.29 0.202 16.0, 32.5 0.82
B6.A-Chr9 f 23.4 2.39   8 0.844 0.102 21.0, 29.0 0.63
B6.A-Chr9 m 20.6 4.34   6 1.77 0.211 14.5, 26.5 0.42
B6.A-ChrX f 20.0 14.3   8 5.04 0.713 2.0, 52.0 -0.58
B6.A-ChrX m 18.8 6.95   8 2.46 0.369 3.5, 25.0 -0.1
B6.A-ChrY f 17.2 5.29   8 1.87 0.307 6.5, 23.5 -1.59
B6.A-ChrY m 19.4 3.41   8 1.21 0.176 14.5, 24.5 0.07
C57BL/6J f 18.1 4.34   8 1.53 0.239 12.5, 26.5 -1.26
C57BL/6J m 13.9 5.3   8 1.88 0.382 8.0, 22.5 -1.51


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 27.3125 2.5304 32.2907 22.3343
A/J m 25.6875 2.5304 30.6657 20.7093
B6.A-Chr1 f 19.0625 2.5304 24.0407 14.0843
B6.A-Chr1 m 19.5625 2.5304 24.5407 14.5843
B6.A-Chr10 f 26.7222 2.3857 31.4157 22.0287
B6.A-Chr10 m 21.25 2.5304 26.2282 16.2718
B6.A-Chr11 f 21.875 2.5304 26.8532 16.8968
B6.A-Chr11 m 17.75 2.5304 22.7282 12.7718
B6.A-Chr12 f 24.25 2.5304 29.2282 19.2718
B6.A-Chr12 m 23.3125 2.5304 28.2907 18.3343
B6.A-Chr13 f 20.6875 2.5304 25.6657 15.7093
B6.A-Chr13 m 13.875 2.5304 18.8532 8.8968
B6.A-Chr14 f 23.9375 2.5304 28.9157 18.9593
B6.A-Chr14 m 17.4375 2.5304 22.4157 12.4593
B6.A-Chr15 f 19.2778 2.3857 23.9713 14.5843
B6.A-Chr15 m 16.5714 2.7052 21.8934 11.2495
B6.A-Chr16 f 20.8125 2.5304 25.7907 15.8343
B6.A-Chr16 m 18.625 2.5304 23.6032 13.6468
B6.A-Chr17 f 25.75 2.5304 30.7282 20.7718
B6.A-Chr17 m 22.7143 2.7052 28.0362 17.3923
B6.A-Chr18 f 22.1875 2.5304 27.1657 17.2093
B6.A-Chr18 m 20.5625 2.5304 25.5407 15.5843
B6.A-Chr19 f 20.5625 2.5304 25.5407 15.5843
B6.A-Chr19 m 19.8125 2.5304 24.7907 14.8343
B6.A-Chr2 f 17.125 2.5304 22.1032 12.1468
B6.A-Chr2 m 18.25 2.5304 23.2282 13.2718
B6.A-Chr3 f 19.875 2.5304 24.8532 14.8968
B6.A-Chr3 m 21.75 2.5304 26.7282 16.7718
B6.A-Chr4 f 22.5625 2.5304 27.5407 17.5843
B6.A-Chr4 m 10.25 2.5304 15.2282 5.2718
B6.A-Chr5 f 22.625 2.5304 27.6032 17.6468
B6.A-Chr5 m 15.75 2.5304 20.7282 10.7718
B6.A-Chr6 f 19.8571 2.7052 25.1791 14.5352
B6.A-Chr6 m 20.0625 2.5304 25.0407 15.0843
B6.A-Chr7 f 20.9375 2.5304 25.9157 15.9593
B6.A-Chr7 m 22.25 2.5304 27.2282 17.2718
B6.A-Chr8 f 23.3125 2.5304 28.2907 18.3343
B6.A-Chr8 m 22.0 2.0661 26.0647 17.9353
B6.A-Chr9 f 23.375 2.5304 28.3532 18.3968
B6.A-Chr9 m 20.5833 2.9219 26.3317 14.835
B6.A-ChrX f 20.0 2.5304 24.9782 15.0218
B6.A-ChrX m 18.8125 2.5304 23.7907 13.8343
B6.A-ChrY f 17.25 2.5304 22.2282 12.2718
B6.A-ChrY m 19.375 2.5304 24.3532 14.3968
C57BL/6J f 18.125 2.5304 23.1032 13.1468
C57BL/6J m 13.875 2.5304 18.8532 8.8968


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 26.5 1.7893 30.0201 22.9799
B6.A-Chr1 both 19.3125 1.7893 22.8326 15.7924
B6.A-Chr10 both 23.9861 1.7389 27.4071 20.5651
B6.A-Chr11 both 19.8125 1.7893 23.3326 16.2924
B6.A-Chr12 both 23.7812 1.7893 27.3014 20.2611
B6.A-Chr13 both 17.2813 1.7893 20.8014 13.7611
B6.A-Chr14 both 20.6875 1.7893 24.2076 17.1674
B6.A-Chr15 both 17.9246 1.8034 21.4726 14.3766
B6.A-Chr16 both 19.7187 1.7893 23.2389 16.1986
B6.A-Chr17 both 24.2321 1.8521 27.8758 20.5884
B6.A-Chr18 both 21.375 1.7893 24.8951 17.8549
B6.A-Chr19 both 20.1875 1.7893 23.7076 16.6674
B6.A-Chr2 both 17.6875 1.7893 21.2076 14.1674
B6.A-Chr3 both 20.8125 1.7893 24.3326 17.2924
B6.A-Chr4 both 16.4063 1.7893 19.9264 12.8861
B6.A-Chr5 both 19.1875 1.7893 22.7076 15.6674
B6.A-Chr6 both 19.9598 1.8521 23.6035 16.3161
B6.A-Chr7 both 21.5937 1.7893 25.1139 18.0736
B6.A-Chr8 both 22.6562 1.6334 25.8697 19.4428
B6.A-Chr9 both 21.9792 1.9327 25.7814 18.177
B6.A-ChrX both 19.4062 1.7893 22.9264 15.8861
B6.A-ChrY both 18.3125 1.7893 21.8326 14.7924
C57BL/6J both 16.0 1.7893 19.5201 12.4799




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA