Project measure / variable:   Donahue2   ultimate_strength

ID, description, units MPD:17231   ultimate_strength   estimated ultimate strength   [N]  
Data set, strains Donahue2   inbred   10 strains     sex: both     age: 16wks
Procedure biomechanical test
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  STRAIN COMPARISON PLOT
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Donahue2 - estimated ultimate strength



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means296   N 279   N
Median of the strain means294   N 290   N
SD of the strain means± 53.7 ± 51.3
Coefficient of variation (CV)0.181 0.184
Min–max range of strain means217   –   409   N 206   –   359   N
Mean sample size per strain9.9   mice 10.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 13546.017 13546.017 7.818 0.0057
strain 9 464046.9946 51560.7772 29.7579 < 0.0001
sex:strain 9 29355.1218 3261.6802 1.8825 0.0567
Residuals 190 329208.4618 1732.6761


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 254.0 42.1   10 13.3 0.166 183.0, 308.0 -0.79
129S1/SvImJ m 278.0 38.2   15 9.85 0.137 200.0, 322.0 -0.02
BALB/cJ f 329.0 50.5   10 16.0 0.153 238.0, 391.0 0.61
BALB/cJ m 311.0 49.6   10 15.7 0.16 225.0, 384.0 0.63
C3H/HeJ f 409.0 59.5   9 19.8 0.145 327.0, 491.0 2.1
C3H/HeJ m 359.0 44.5   10 14.1 0.124 279.0, 426.0 1.56
C57BL/6J f 217.0 36.5   10 11.5 0.168 162.0, 258.0 -1.48
C57BL/6J m 206.0 31.2   12 9.01 0.151 129.0, 239.0 -1.42
C58/J f 269.0 41.1   10 13.0 0.153 228.0, 361.0 -0.51
C58/J m 225.0 33.9   10 10.7 0.151 176.0, 274.0 -1.05
FVB/NJ f 256.0 27.4   10 8.67 0.107 213.0, 290.0 -0.75
FVB/NJ m 211.0 33.4   9 11.1 0.158 173.0, 276.0 -1.32
NZB/BlNJ f 331.0 28.1   11 8.47 0.0848 276.0, 379.0 0.64
NZB/BlNJ m 304.0 25.5   13 7.07 0.084 244.0, 349.0 0.49
PWK/PhJ f 281.0 41.1   12 11.9 0.146 218.0, 359.0 -0.29
PWK/PhJ m 268.0 48.5   11 14.6 0.181 209.0, 366.0 -0.21
SJL/J f 310.0 52.7   8 18.6 0.17 244.0, 375.0 0.25
SJL/J m 302.0 45.8   11 13.8 0.152 211.0, 369.0 0.45
SWR/J f 308.0 55.8   9 18.6 0.181 244.0, 378.0 0.22
SWR/J m 325.0 40.3   10 12.7 0.124 266.0, 381.0 0.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 253.6 13.1631 279.5646 227.6354
129S1/SvImJ m 278.1333 10.7476 299.3334 256.9333
BALB/cJ f 329.3 13.1631 355.2646 303.3354
BALB/cJ m 310.6 13.1631 336.5646 284.6354
C3H/HeJ f 408.7778 13.8751 436.1469 381.4087
C3H/HeJ m 359.4 13.1631 385.3646 333.4354
C57BL/6J f 216.9 13.1631 242.8646 190.9354
C57BL/6J m 206.1667 12.0162 229.869 182.4643
C58/J f 268.8 13.1631 294.7646 242.8354
C58/J m 225.1 13.1631 251.0646 199.1354
FVB/NJ f 256.4 13.1631 282.3646 230.4354
FVB/NJ m 210.8889 13.8751 238.258 183.5198
NZB/BlNJ f 331.3636 12.5505 356.1199 306.6073
NZB/BlNJ m 303.6154 11.5448 326.3879 280.8429
PWK/PhJ f 280.6667 12.0162 304.369 256.9643
PWK/PhJ m 267.5455 12.5505 292.3017 242.7892
SJL/J f 310.0 14.7168 339.0293 280.9707
SJL/J m 301.6364 12.5505 326.3927 276.8801
SWR/J f 308.2222 13.8751 335.5913 280.8531
SWR/J m 324.6 13.1631 350.5646 298.6354


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 265.8667 8.4968 282.6268 249.1066
BALB/cJ both 319.95 9.3077 338.3098 301.5902
C3H/HeJ both 384.0889 9.5628 402.9517 365.226
C57BL/6J both 211.5333 8.9115 229.1115 193.9552
C58/J both 246.95 9.3077 265.3098 228.5902
FVB/NJ both 233.6444 9.5628 252.5073 214.7816
NZB/BlNJ both 317.4895 8.5264 334.3081 300.6709
PWK/PhJ both 274.1061 8.6877 291.2428 256.9693
SJL/J both 305.8182 9.6708 324.8942 286.7422
SWR/J both 316.4111 9.5628 335.274 297.5483




  GWAS USING LINEAR MIXED MODELS