Project measure / variable:   Donahue2   femur_yield_load

ID, description, units MPD:17209   femur_yield_load   load at 95% break load   [N]  
Data set, strains Donahue2   inbred   10 strains     sex: both     age: 16wks
Procedure biomechanical test
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  STRAIN COMPARISON PLOT
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Donahue2 - load at 95% break load



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means13.8   N 15.1   N
Median of the strain means13.4   N 13.9   N
SD of the strain means± 4.00 ± 4.31
Coefficient of variation (CV)0.290 0.285
Min–max range of strain means9.29   –   23.5   N 10.1   –   23.7   N
Mean sample size per strain10.0   mice 11.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 125.2287 125.2287 18.9857 < 0.0001
strain 9 2792.6414 310.2935 47.0431 < 0.0001
sex:strain 9 337.5951 37.5106 5.6869 < 0.0001
Residuals 192 1266.4208 6.5959


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 14.1 2.45   10 0.774 0.174 10.5, 18.4 0.08
129S1/SvImJ m 14.5 3.45   15 0.89 0.237 3.8, 19.4 -0.14
BALB/cJ f 16.4 1.51   10 0.478 0.0924 13.7, 18.5 0.65
BALB/cJ m 18.7 4.31   10 1.36 0.23 15.5, 30.3 0.84
C3H/HeJ f 23.5 1.95   9 0.649 0.0827 20.9, 26.2 2.43
C3H/HeJ m 23.7 2.77   11 0.836 0.117 19.8, 28.4 2.0
C57BL/6J f 10.3 2.38   10 0.752 0.232 7.7, 14.3 -0.87
C57BL/6J m 17.5 3.21   12 0.928 0.184 12.8, 22.5 0.56
C58/J f 13.1 2.55   10 0.805 0.195 8.07, 18.0 -0.17
C58/J m 13.1 1.6   10 0.507 0.123 10.7, 15.9 -0.46
FVB/NJ f 13.7 4.86   11 1.47 0.356 9.75, 27.7 -0.02
FVB/NJ m 11.2 1.29   9 0.429 0.115 9.34, 13.9 -0.91
NZB/BlNJ f 14.2 1.59   11 0.479 0.112 10.9, 16.3 0.1
NZB/BlNJ m 18.0 2.09   13 0.578 0.116 15.7, 22.2 0.67
PWK/PhJ f 11.0 1.82   12 0.525 0.165 8.42, 15.2 -0.7
PWK/PhJ m 10.8 2.56   11 0.771 0.237 8.34, 16.3 -1.0
SJL/J f 12.3 0.669   8 0.236 0.0543 11.2, 13.3 -0.37
SJL/J m 13.4 2.1   11 0.634 0.157 9.48, 17.9 -0.39
SWR/J f 9.29 0.82   9 0.273 0.0883 7.77, 10.2 -1.12
SWR/J m 10.1 1.61   10 0.508 0.158 7.98, 12.8 -1.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 14.1 0.8122 15.7019 12.4981
129S1/SvImJ m 14.5333 0.6631 15.8413 13.2254
BALB/cJ f 16.35 0.8122 17.9519 14.7481
BALB/cJ m 18.7 0.8122 20.3019 17.0981
C3H/HeJ f 23.5333 0.8561 25.2219 21.8448
C3H/HeJ m 23.6909 0.7744 25.2183 22.1636
C57BL/6J f 10.267 0.8122 11.8689 8.6651
C57BL/6J m 17.475 0.7414 18.9373 16.0127
C58/J f 13.067 0.8122 14.6689 11.4651
C58/J m 13.09 0.8122 14.6919 11.4881
FVB/NJ f 13.6773 0.7744 15.2046 12.1499
FVB/NJ m 11.1711 0.8561 12.8597 9.4826
NZB/BlNJ f 14.2273 0.7744 15.7546 12.6999
NZB/BlNJ m 18.0077 0.7123 19.4126 16.6027
PWK/PhJ f 11.0083 0.7414 12.4707 9.546
PWK/PhJ m 10.7909 0.7744 12.3183 9.2636
SJL/J f 12.3125 0.908 14.1035 10.5215
SJL/J m 13.3527 0.7744 14.8801 11.8254
SWR/J f 9.2878 0.8561 10.9763 7.5992
SWR/J m 10.129 0.8122 11.7309 8.5271


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 14.3167 0.5242 15.3507 13.2827
BALB/cJ both 17.525 0.5743 18.6577 16.3923
C3H/HeJ both 23.6121 0.5772 24.7505 22.4737
C57BL/6J both 13.871 0.5498 14.9555 12.7865
C58/J both 13.0785 0.5743 14.2112 11.9458
FVB/NJ both 12.4242 0.5772 13.5626 11.2858
NZB/BlNJ both 16.1175 0.5261 17.1551 15.0799
PWK/PhJ both 10.8996 0.536 11.9569 9.8424
SJL/J both 12.8326 0.5967 14.0095 11.6557
SWR/J both 9.7084 0.59 10.8721 8.5446




  GWAS USING LINEAR MIXED MODELS