Project measure / variable:   Schulz1   TLC

ID, description, units MPD:1608   TLC   total lung capacity   [µL]  
Data set, strains Schulz1   inbred   7 strains     sex: both     age: 12-14wks
Procedure ventilator
Ontology mappings

  STRAIN COMPARISON PLOT
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Schulz1 - total lung capacity



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means1266   µL 1431   µL
Median of the strain means1232   µL 1353   µL
SD of the strain means± 139 ± 204
Coefficient of variation (CV)0.110 0.143
Min–max range of strain means1129   –   1461   µL 1226   –   1837   µL
Mean sample size per strain14.6   mice 14.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1369007.0586 1369007.0586 95.9464 < 0.0001
strain 6 4738080.9309 789680.1552 55.3444 < 0.0001
sex:strain 6 551256.7129 91876.1188 6.4391 < 0.0001
Residuals 192 2739544.6422 14268.4617


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1289.0 95.8   15 24.7 0.0743 1120.0, 1523.0 0.17
129S1/SvImJ m 1334.0 91.7   16 22.9 0.0687 1056.0, 1512.0 -0.47
A/J f 1232.0 89.6   16 22.4 0.0727 1067.0, 1355.0 -0.24
A/J m 1401.0 137.0   14 36.7 0.098 1091.0, 1656.0 -0.15
BALB/cByJ f 1461.0 81.0   15 20.9 0.0555 1341.0, 1627.0 1.4
BALB/cByJ m 1548.0 75.6   16 18.9 0.0488 1406.0, 1706.0 0.57
C3H/HeJ f 1443.0 105.0   13 29.1 0.0727 1278.0, 1621.0 1.27
C3H/HeJ m 1837.0 297.0   14 79.4 0.162 1476.0, 2298.0 1.99
C57BL/6J f 1174.0 84.4   14 22.6 0.0719 982.0, 1279.0 -0.66
C57BL/6J m 1353.0 125.0   13 34.8 0.0927 1025.0, 1478.0 -0.38
FVB/NJ f 1129.0 78.5   16 19.6 0.0695 1015.0, 1343.0 -0.98
FVB/NJ m 1316.0 114.0   15 29.3 0.0863 965.0, 1437.0 -0.56
SWR/J f 1131.0 57.4   13 15.9 0.0508 1014.0, 1219.0 -0.97
SWR/J m 1226.0 67.6   16 16.9 0.0551 1137.0, 1431.0 -1.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1288.8 30.842 1349.6327 1227.9673
129S1/SvImJ m 1334.375 29.8627 1393.276 1275.474
A/J f 1232.5 29.8627 1291.401 1173.599
A/J m 1401.0 31.9245 1463.9678 1338.0322
BALB/cByJ f 1460.9333 30.842 1521.766 1400.1006
BALB/cByJ m 1547.9375 29.8627 1606.8385 1489.0365
C3H/HeJ f 1442.6154 33.1297 1507.9602 1377.2706
C3H/HeJ m 1836.9286 31.9245 1899.8964 1773.9607
C57BL/6J f 1173.6429 31.9245 1236.6107 1110.675
C57BL/6J m 1353.0769 33.1297 1418.4217 1287.7321
FVB/NJ f 1129.3125 29.8627 1188.2135 1070.4115
FVB/NJ m 1316.4667 30.842 1377.2994 1255.634
SWR/J f 1130.7692 33.1297 1196.114 1065.4244
SWR/J m 1226.25 29.8627 1285.151 1167.349


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1311.5875 21.4651 1353.9253 1269.2497
A/J both 1316.75 21.8572 1359.8611 1273.6389
BALB/cByJ both 1504.4354 21.4651 1546.7732 1462.0976
C3H/HeJ both 1639.772 23.0041 1685.1451 1594.3988
C57BL/6J both 1263.3599 23.0041 1308.733 1217.9867
FVB/NJ both 1222.8896 21.4651 1265.2274 1180.5518
SWR/J both 1178.5096 22.3011 1222.4962 1134.523




  GWAS USING LINEAR MIXED MODELS