Project measure / variable:   Flaherty1   lat

ID, description, units MPD:11804   lat   latency to enter open quadrant   [s]  
Data set, strains Flaherty1   inbred   8 strains     sex: both     age: 8-9wks
Procedure elevated zero maze
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  STRAIN COMPARISON PLOT
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Flaherty1 - latency to enter open quadrant



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means55.6   s 47.8   s
Median of the strain means30.7   s 37.1   s
SD of the strain means± 54.4 ± 41.4
Coefficient of variation (CV)0.979 0.867
Min–max range of strain means6.34   –   140   s 8.34   –   127   s
Mean sample size per strain19.9   mice 19.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4627.3606 4627.3606 0.8262 0.3641
strain 7 612524.5622 87503.5089 15.6228 < 0.0001
sex:strain 7 38743.8129 5534.8304 0.9882 0.4398
Residuals 301 1685903.7413 5601.0091


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 108.0 119.0   20 26.7 1.11 8.3, 300.0 0.96
129S1/SvImJ m 49.9 58.1   20 13.0 1.16 0.8, 215.0 0.05
A/J f 140.0 134.0   20 29.9 0.953 2.1, 300.0 1.55
A/J m 127.0 118.0   20 26.5 0.933 6.9, 300.0 1.91
BALB/cByJ f 47.2 91.0   20 20.4 1.93 0.2, 300.0 -0.15
BALB/cByJ m 45.6 86.2   20 19.3 1.89 0.7, 291.0 -0.05
C3H/HeJ f 11.3 11.1   20 2.49 0.982 0.2, 48.8 -0.81
C3H/HeJ m 8.34 6.76   19 1.55 0.811 0.4, 22.0 -0.95
C57BL/6J f 6.34 8.54   20 1.91 1.35 0.2, 33.6 -0.9
C57BL/6J m 28.6 43.3   20 9.69 1.52 1.2, 156.0 -0.46
CBA/J f 10.5 8.59   20 1.92 0.815 0.3, 26.6 -0.83
CBA/J m 18.2 19.1   19 4.39 1.05 1.3, 62.3 -0.71
DBA/2J f 107.0 96.5   20 21.6 0.901 1.4, 300.0 0.95
DBA/2J m 90.5 105.0   20 23.6 1.16 0.2, 300.0 1.03
FVB/NJ f 14.2 17.6   19 4.03 1.24 0.1, 53.7 -0.76
FVB/NJ m 14.4 15.6   20 3.49 1.08 0.7, 65.4 -0.81


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 107.745 16.7347 140.6768 74.8132
129S1/SvImJ m 49.915 16.7347 82.8468 16.9832
A/J f 140.49 16.7347 173.4218 107.5582
A/J m 126.785 16.7347 159.7168 93.8532
BALB/cByJ f 47.18 16.7347 80.1118 14.2482
BALB/cByJ m 45.575 16.7347 78.5068 12.6432
C3H/HeJ f 11.32 16.7347 44.2518 0.0
C3H/HeJ m 8.3368 17.1694 42.1242 0.0
C57BL/6J f 6.34 16.7347 39.2718 0.0
C57BL/6J m 28.595 16.7347 61.5268 0.0
CBA/J f 10.535 16.7347 43.4668 0.0
CBA/J m 18.1684 17.1694 51.9558 0.0
DBA/2J f 107.09 16.7347 140.0218 74.1582
DBA/2J m 90.52 16.7347 123.4518 57.5882
FVB/NJ f 14.1684 17.1694 47.9558 0.0
FVB/NJ m 14.43 16.7347 47.3618 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 78.83 11.8332 102.1163 55.5437
A/J both 133.6375 11.8332 156.9238 110.3512
BALB/cByJ both 46.3775 11.8332 69.6638 23.0912
C3H/HeJ both 9.8284 11.9879 33.4192 0.0
C57BL/6J both 17.4675 11.8332 40.7538 0.0
CBA/J both 14.3517 11.9879 37.9424 0.0
DBA/2J both 98.805 11.8332 122.0913 75.5187
FVB/NJ both 14.2992 11.9879 37.8899 0.0




  GWAS USING LINEAR MIXED MODELS