Project measure / variable:   Wahlsten1   pct_open

ID, description, units MPD:10852   pct_open   percentage of time spent in open arms vs closed   [%]  
Data set, strains Wahlsten1   inbred   21 strains     sex: both     age: 9wks
Procedure elevated plus maze
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  STRAIN COMPARISON PLOT
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Wahlsten1 - percentage of time spent in open arms vs closed



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains21 strains
Mean of the strain means37.8   % 37.6   %
Median of the strain means38.1   % 36.3   %
SD of the strain means± 15.9 ± 16.4
Coefficient of variation (CV)0.422 0.437
Min–max range of strain means6.78   –   65.6   % 8.21   –   71.9   %
Mean sample size per strain8.9   mice 8.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 18.3969 18.3969 0.0392 0.8432
strain 20 69434.3755 3471.7188 7.3964 < 0.0001
sex:strain 20 11533.3577 576.6679 1.2286 0.2279
Residuals 329 154426.147 469.3804


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 65.6 38.9   7 14.7 0.593 10.9, 99.8 1.75
129S1/SvImJ m 68.4 32.1   10 10.2 0.47 1.87
A/J f 6.78 17.6   8 6.21 2.59 -1.94
A/J m 28.0 35.8   8 12.6 1.28 -0.58
AKR/J f 17.9 9.05   8 3.2 0.506 2.22, 27.8 -1.25
AKR/J m 13.7 10.6   8 3.76 0.777 0.27, 29.4 -1.45
BALB/cByJ f 33.0 28.3   10 8.93 0.857 -0.3
BALB/cByJ m 44.5 17.9   8 6.32 0.402 17.8, 67.3 0.42
BTBR T+ Itpr3tf/J f 49.8 19.8   12 5.72 0.398 13.5, 81.7 0.76
BTBR T+ Itpr3tf/J m 71.9 11.4   5 5.09 0.159 59.4, 86.8 2.09
C3H/HeJ f 32.0 21.1   8 7.46 0.66 0.27, 62.7 -0.36
C3H/HeJ m 36.3 19.5   8 6.88 0.536 0.69, 72.1 -0.08
C57BL/6J f 43.2 13.3   8 4.69 0.307 20.6, 59.1 0.34
C57BL/6J m 35.1 21.0   10 6.64 0.599 10.9, 64.0 -0.15
C57L/J f 28.3 12.5   10 3.95 0.441 10.9, 53.8 -0.59
C57L/J m 36.2 9.4   6 3.84 0.26 22.9, 46.1 -0.09
C58/J f 47.8 26.1   8 9.22 0.545 11.6, 93.4 0.63
C58/J m 28.6 11.9   10 3.75 0.414 11.6, 45.7 -0.55
CAST/EiJ f 64.1 29.4   8 10.4 0.458 3.43, 98.2 1.65
CAST/EiJ m 39.4 19.8   9 6.59 0.503 12.1, 61.4 0.11
DBA/2J f 15.9 11.5   8 4.06 0.721 1.72, 35.8 -1.37
DBA/2J m 17.8 10.3   8 3.65 0.581 4.27, 35.1 -1.2
FVB/NJ f 38.1 15.2   10 4.8 0.399 11.0, 57.5 0.02
FVB/NJ m 50.6 9.65   11 2.91 0.191 35.2, 66.4 0.79
MOLF/EiJ f 19.3 7.44   8 2.63 0.386 5.79, 31.4 -1.16
MOLF/EiJ m 17.9 9.54   7 3.61 0.532 0.99, 29.2 -1.2
NOD/ShiLtJ f 47.2 31.8   12 9.18 0.674 1.46, 100.0 0.59
NOD/ShiLtJ m 39.3 26.0   12 7.5 0.661 1.14, 81.8 0.1
NZB/BlNJ f 30.1 18.0   6 7.33 0.596 -0.48
NZB/BlNJ m 29.8 20.6   12 5.95 0.693 0.45, 73.0 -0.47
PERA/EiJ f 39.3 19.6   10 6.2 0.498 8.61, 68.3 0.1
PERA/EiJ m 33.4 22.2   11 6.69 0.664 -0.26
PL/J f 41.8 23.5   12 6.79 0.563 0.42, 89.3 0.25
PL/J m 45.0 16.0   8 5.67 0.357 20.1, 70.6 0.45
SJL/J f 30.4 20.0   8 7.08 0.658 0.38, 60.3 -0.46
SJL/J m 38.1 28.3   10 8.95 0.743 1.17, 73.4 0.03
SM/J f 59.7 18.4   14 4.91 0.308 14.2, 88.1 1.38
SM/J m 55.0 30.8   8 10.9 0.56 0.5, 87.4 1.06
SPRET/EiJ f 29.1 44.1   6 18.0 1.51 -0.54
SPRET/EiJ m 8.21 3.67   2   2.6 0.447 5.61, 10.8 -1.79
SWR/J f 53.4 13.2   9 4.41 0.248 41.9, 79.9 0.98
SWR/J m 52.4 16.4   10 5.18 0.313 22.1, 77.6 0.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 65.6429 8.1887 81.7516 49.5341
129S1/SvImJ m 68.36 6.8511 81.8376 54.8824
A/J f 6.775 7.6598 21.8434 0.0
A/J m 28.0375 7.6598 43.1059 12.9691
AKR/J f 17.9025 7.6598 32.9709 2.8341
AKR/J m 13.6962 7.6598 28.7646 0.0
BALB/cByJ f 32.974 6.8511 46.4516 19.4964
BALB/cByJ m 44.4625 7.6598 59.5309 29.3941
BTBR T+ Itpr3tf/J f 49.8167 6.2542 62.1199 37.5134
BTBR T+ Itpr3tf/J m 71.86 9.689 90.9201 52.7999
C3H/HeJ f 31.9713 7.6598 47.0396 16.9029
C3H/HeJ m 36.3112 7.6598 51.3796 21.2429
C57BL/6J f 43.2125 7.6598 58.2809 28.1441
C57BL/6J m 35.07 6.8511 48.5476 21.5924
C57L/J f 28.32 6.8511 41.7976 14.8424
C57L/J m 36.1833 8.8448 53.5828 18.7839
C58/J f 47.8125 7.6598 62.8809 32.7441
C58/J m 28.62 6.8511 42.0976 15.1424
CAST/EiJ f 64.1288 7.6598 79.1971 49.0604
CAST/EiJ m 39.3556 7.2217 53.5621 25.149
DBA/2J f 15.9288 7.6598 30.9971 0.8604
DBA/2J m 17.7725 7.6598 32.8409 2.7041
FVB/NJ f 38.06 6.8511 51.5376 24.5824
FVB/NJ m 50.5909 6.5323 63.4413 37.7406
MOLF/EiJ f 19.2863 7.6598 34.3546 4.2179
MOLF/EiJ m 17.9271 8.1887 34.0359 1.8184
NOD/ShiLtJ f 47.1975 6.2542 59.5008 34.8942
NOD/ShiLtJ m 39.3167 6.2542 51.6199 27.0134
NZB/BlNJ f 30.1333 8.8448 47.5328 12.7339
NZB/BlNJ m 29.75 6.2542 42.0533 17.4467
PERA/EiJ f 39.331 6.8511 52.8086 25.8534
PERA/EiJ m 33.4091 6.5323 46.2594 20.5587
PL/J f 41.7883 6.2542 54.0916 29.4851
PL/J m 44.95 7.6598 60.0184 29.8816
SJL/J f 30.4225 7.6598 45.4909 15.3541
SJL/J m 38.1 6.8511 51.5776 24.6224
SM/J f 59.6857 5.7903 71.0763 48.2951
SM/J m 54.9625 7.6598 70.0309 39.8941
SPRET/EiJ f 29.1117 8.8448 46.5111 11.7122
SPRET/EiJ m 8.205 15.3196 38.3417 0.0
SWR/J f 53.4444 7.2217 67.651 39.2379
SWR/J m 52.39 6.8511 65.8676 38.9124


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 67.0014 5.3384 77.5031 56.4998
A/J both 17.4062 5.4163 28.0612 6.7513
AKR/J both 15.7994 5.4163 26.4543 5.1444
BALB/cByJ both 38.7183 5.1384 48.8264 28.6101
BTBR T+ Itpr3tf/J both 60.8383 5.7661 72.1814 49.4953
C3H/HeJ both 34.1412 5.4163 44.7962 23.4863
C57BL/6J both 39.1413 5.1384 49.2494 29.0331
C57L/J both 32.2517 5.5939 43.256 21.2473
C58/J both 38.2162 5.1384 48.3244 28.1081
CAST/EiJ both 51.7422 5.2637 62.0969 41.3874
DBA/2J both 16.8506 5.4163 27.5056 6.1957
FVB/NJ both 44.3255 4.7331 53.6364 35.0145
MOLF/EiJ both 18.6067 5.6064 29.6356 7.5778
NOD/ShiLtJ both 43.2571 4.4224 51.9568 34.5574
NZB/BlNJ both 29.9417 5.4163 40.5966 19.2867
PERA/EiJ both 36.37 4.7331 45.681 27.0591
PL/J both 43.3692 4.9444 53.0958 33.6426
SJL/J both 34.2613 5.1384 44.3694 24.1531
SM/J both 57.3241 4.801 66.7687 47.8795
SPRET/EiJ both 18.6583 8.8448 36.0578 1.2589
SWR/J both 52.9172 4.9772 62.7084 43.126




  GWAS USING LINEAR MIXED MODELS