Intervention:   ethanol          

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg) Year
    Bennett3 37501 alcohol quantification ethanol blood ethanol concentration (BEC)   [mg/mL]     first loss of balance (ataxia)    first regain of balance    second regain of balance ILSXISS w/par 72 both 8-14wks N=5 2007
    Bennett3 37504 alcohol quantification ethanol acute functional tolerance to EtOH (AFT1 = BEC 2 minus BEC 1)   [mg/mL]  AFT1 ILSXISS w/par 72 both 8-14wks N=5 2007
    Bennett3 37505 alcohol quantification ethanol acute functional tolerance to EtOH (AFT2 = BEC 2 minus BEC 0)   [mg/mL]  AFT2 ILSXISS w/par 72 both 8-14wks N=5 2007
Chesler6 27104 rotarod ethanol  2.0 g/kg rotarod: two trial post alcohol average minus pre trial latency to fall off rotarod (latency difference in seconds)   [second]  Rotarod_atax QTL population both 9-34wks N=187 2012
Chesler6 27105 body temperature ethanol  3.5 g/kg post alcohol minus pre alcohol body temperature (degrees Celsius)   [° C]  Hypotherm QTL population both 9-34wks N=187 2012
Chesler6 27106 behavior observation ethanol  3.5 g/kg alcohol induced Loss of Righting Reflex (latency to return of reflex in seconds)   [second]  LORR QTL population both 9-34wks N=187 2012
Chesler6 27107 alcohol quantification ethanol  3.5 g/kg Blood Ethanol Concentration at return of righting reflex (latency to return in seconds)   [mg/mL]  LORR_BEC QTL population both 9-34wks N=187 2012
Chesler6 27109 rotarod ethanol  2.0 g/kg rotarod: first alcohol trial performance (latency to fall in seconds)   [second]  RotaTest1 QTL population both 9-34wks N=187 2012
    Crabbe1 15403 balance beam ethanol missteps crossing balance beam   [n]     12.7mm beam:    control    i.p. doses g/kg:    1.0    1.2    1.4 inbred 7 both 8-16wks N=4 2003
    Crabbe1 15404 balance beam ethanol missteps crossing balance beam   [n]     15.8mm beam:    control    i.p. doses g/kg:    1.0    1.2    1.4 inbred 8 both 8-16wks N=5 2003
    Crabbe1 15405 balance beam ethanol missteps crossing balance beam   [n]     19.0mm beam:    control    i.p. doses g/kg:    1.0    1.2    1.4 inbred 8 both 8-16wks N=4 2003
    Crabbe1 15406 grid test ethanol grid habituation, distance traveled   [cm]     control    i.p. doses g/kg:    1.5    2.0    2.5 inbred 8 both 8-16wks N=5 2003
    Crabbe1 15407 grid test ethanol grid habituation, missteps per cm   [n/cm]     control    i.p. doses g/kg:    1.5    2.0    2.5 inbred 8 both 8-16wks N=5 2003
    Crabbe3 15810 rotarod ethanol fixed speed 3 rpm rotarod (latency to fall)   [s]     ethanol i.p. g/kg:    1    2    3 inbred 9 both 9-17wks N=4 2003
    Crabbe3 15815 rotarod ethanol fixed speed 6 rpm rotarod (latency to fall)   [s]     ethanol i.p. g/kg:    1    2    3 inbred 9 both 9-17wks N=4 2003
    Crabbe3 15820 rotarod ethanol fixed speed 10 rpm rotarod (latency to fall)   [s]     ethanol i.p. g/kg:    1    2    3 inbred 7 both 9-17wks N=3 2003
    Crabbe3 15840 rotarod ethanol accelerating rotarod (latency to fall), test day 1 20 rpm/min (ARR1)   [s]     baseline    ethanol    Δchange (ethanol effect) inbred 8 both 9-17wks N=6 2003
    Crabbe3 15845 rotarod ethanol accelerating rotarod (latency to fall), test day 2 30 rpm/min (ARR1)   [s]     baseline    ethanol    Δchange (ethanol effect) inbred 8 both 9-17wks N=5 2003
    Crabbe3 15855 rotarod ethanol accelerating rotarod (latency to fall), test 20 rpm/min (ARR2)   [s]     baseline    ethanol inbred 21 both 9-17wks N=9 2003
    Crabbe3 15857 rotarod ethanol  2g/kg i.p. accelerating rotarod (ARR2) average latency of post-injection trials minus pre-injection trials (ETPOST - ETBASE) (20 rpm/min)   [s]  ARR2_chg_20rpm inbred 21 both 9-17wks N=9 2003
    Crabbe4 19101 vertical wire mesh ethanol  2g/kg i.p. latency to fall from a vertical wire mesh grid 30 min post-injection   [s]  latency_screen30 inbred 8 both 9-10wks N=5 2003
    Crabbe4 19102 dowel balance test ethanol latency to fall 0 min post-injection   [s]     9.5mm    15.8mm inbred 8 both 12-16wks N=4 2003
    Crabbe4 19103 dowel balance test ethanol latency to fall, 30 min post-injection   [s]     9.5mm    15.8mm inbred 8 both 12-16wks N=4 2003
    Crabbe4 19106 grip strength ethanol grip strength test: peak force applied   [g]     baseline    30min after ethanol inbred 21 both 7-12wks N=6 2003
    Crabbe4 19108 grip strength ethanol  2g/kg i.p. change in peak force applied (T0-T30) post-injection, grip strength test   [g]  gripEtOHeffect inbred 21 both 7-12wks N=6 2003
    Crabbe4 19109 grip strength ethanol  2g/kg i.p. percent change in average latency to fall post-injection, grip strength test   [%]  pct_gripchange inbred 21 both 7-12wks N=6 2003
    Crabbe4 19111 alcohol quantification ethanol  2g/kg i.p. blood ethanol concentration (BEC), 35 min post-injection, dowel (15.8 mm) test   [mg/mL]  BEC_dowel15_8 inbred 8 both 12-16wks N=3 2003
    Crabbe4 19112 alcohol quantification ethanol blood ethanol levels post-injection   [mg/mL]     time after ethanol:    30min    60min    105min    150min inbred 21 both 7-12wks N=6 2003
    Crabbe5 19601 parallel rod floor test ethanol distance traveled, 1.6mm rod, 6mm space   [cm]     day1 control    day2 control    day3 ethanol inbred 8 both 8-10wks N=6 2005
    Crabbe5 19603 parallel rod floor test ethanol motor incoordination (errors/distance traveled)
1.6mm rod, 6mm space   [n/cm]
    day1 control    day2 control    day3 ethanol
inbred 8 both 7-14wks N=6 2005
    Metten1 16501 open field test ethanol line crossings, 2.75 g/kg injection   [n]     pre-injection    10min after injection    30min after inbred 9 both 8-11wks N=4 2004
    Metten1 16502 open field test ethanol line crossings, 3.0 g/kg injection   [n]     pre-injection    10min after injection    30min after inbred 9 both 8-11wks N=4 2004
    Metten1 16509 behavior observation ethanol hindlimb splay, 2.75 g/kg injection   [score]     10min after injection    30min after inbred 9 both 8-11wks N=4 2004
    Metten1 16511 behavior observation ethanol hindlimb splay, 3.0 g/kg injection   [score]     10min after injection    30min after inbred 9 both 8-11wks N=4 2004
    Metten1 16513 behavior observation ethanol erratic gait, 2.75 g/kg injection   [score]     10min after injection    30min after inbred 9 both 8-11wks N=4 2004
    Metten1 16515 behavior observation ethanol erratic gait, 3.0 g/kg injection   [score]     10min after injection    30min after inbred 9 both 8-11wks N=4 2004
    Metten2 19503 behavior observation ethanol peak handling-induced convulsion (HIC) score   [score]     control    ethanol    ethanol normalized to controls inbred 15 m 8-15wks N=10 2005
    Metten2 19506 behavior observation ethanol  aerosolized latency to first handling-induced convulsions score used to calculate peak ethanol   [h]  peak_latency inbred 15 m 8-15wks N=11 2005
    Metten2 19507 behavior observation ethanol  aerosolized withdrawal severity during 0-25h (area under curve of handling-induced convulsions scores)   [AUC]  withdrawal_EtOH inbred 15 m 8-15wks N=20 2005
    Metten2 19508 behavior observation ethanol  aerosolized withdrawal severity during 0-25h (area under curve of handling-induced convulsions scores), normalized to controls   [AUC]  withdrawal_EtOHadj inbred 15 m 8-15wks N=11 2005
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Other available data sets:
Data set Procedure What's in this data set Strains
Tested
Sex Age Year
Chesler6 study archive
with ethanol
Sensitivity to ethanol. Baseline and ethanol. blood alcohol concentration, loss of righting reflex, rotarod, body temperature. EtOH QTL population both 2012