GWAS analyses for phenotype

endocrine — hormones — insulin         ELISA  
Naggert1
insulin   [ng/mL]   high-fat diet   18wks
43 strains   age 25-27wks
  Inbred



Please note: EMMAserver is hosted at UCLA on servers not under MPD's control.

These association analyses require that phenotype variables have reasonably normal distributions. EMMAserver supports inbred, AXB, BXA, BXD, BXH, and CXB strains.

• View results of UCLA/ZarLab EMMA analysis for this measurement

    View this measurement's results on the ZarLab web site
    Begin by clicking on Female, Male, or Both (note that clickable links on that site are undecorated and look like any other text). You will then see genome-wide plots. Drill down by clicking on a region of interest in the plots, eventually reaching a view with genome browser tracks and a list of SNP locations with p values. The 132,000 location SNP map was used.

• Generate a phenotype input file formatted for UCLA/ZarLab EMMAserver



References:
    Kirby A, Kang HM, Wade CM, Cotsapas C, Kostem E, Han B, Furlotte N, Kang EY, Rivas M, Bogue MA, Frazer KA, Johnson FM, Beilharz EJ, Cox DR, Eskin E, Daly MJ. Fine mapping in 94 inbred mouse strains using a high-density haplotype resource. Genetics. 2010 Jul;185(3):1081-95. Epub 2010 May 3.     PubMed 20439770     MGI     FullText

    Kang HM, Zaitlen NA, Wade CM, Kirby A, Heckerman D, Daly MJ, Eskin E. Efficient control of population structure in model organism association mapping. Genetics. 2008 Mar;178(3):1709-23.     PubMed 18385116     MGI     FullText