MPD - Projects that involve: high-fat diet

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Projects that involve: high-fat diet

Each of the projects below has phenotype data in MPD.
Links are available for data, protocols, and publications.

Albers1 Data Protocol
Albers JJ, Paigen B Diet-induced changes in plasma phospholipid transfer protein activity, lipids, and lipoproteins in 15 inbred strains of mice

Albers JJ, Pitman W, Wolfbauer G, Cheung MC, Kennedy H, Tu AY, Marcovina SM, Paigen B. Relationship between phospholipid transfer protein activity and HDL level and size among inbred mouse strains. J Lipid Res. 1999 Feb;40(2):295-301. PubMed 9925659 MGI FullText

Cheverud1 Data Protocol
Cheverud JM Diet-induced obesity and diabetes in 19 LGXSM recombinant inbred strains of mice

Cheverud JM, Ehrich TH, Kenney JP, Pletscher LS, Semenkovich CF. Genetic evidence for discordance between obesity- and diabetes-related traits in the LGXSM recombinant inbred mouse strains. Diabetes. 2004 Oct;53(10):2700-8. PubMed 15448104 MGI FullText

Hrbek T, de Brito RA, Wang B, Pletscher LS, Cheverud JM. Genetic characterization of a new set of recombinant inbred lines (LGXSM) formed from the inter-cross of SM/J and LG/J inbred mouse strains. Mamm Genome. 2006 May;17(5):417-29. PubMed 16688532 MGI FullText

Nadeau1 Data Protocol
Nadeau JH, Hill AE Diet-induced obesity survey in C57BL/6J-Chr#^A/J/NaJ mouse chromosome substitution panel (males)

Singer JB, Hill AE, Burrage LC, Olszens KR, Song J, Justice M, O'Brien WE, Conti DV, Witte JS, Lander ES, Nadeau JH. Genetic dissection of complex traits with chromosome substitution strains of mice. Science. 2004 Apr 16;304(5669):445-8. Epub 2004 Mar 18. PubMed 15031436 MGI FullText

Naggert1 Data Protocol
Naggert J, Svenson KL, Smith RV, Paigen B, Peters LL Diet effects on bone mineral density and content, body composition, and plasma glucose, leptin, and insulin levels in 43 inbred strains of mice on a high-fat atherogenic diet

Li R, Svenson KL, Donahue LR, Peters LL, Churchill GA. Relationships of dietary fat, body composition, and bone mineral density in inbred mouse strain panels. Physiol Genomics. 2008 Mar 14;33(1):26-32. Epub 2008 Jan 29. PubMed 18230669 MGI FullText

Svenson KL, Von Smith R, Magnani PA, Suetin HR, Paigen B, Naggert JK, Li R, Churchill GA, Peters LL. Multiple trait measurements in 43 inbred mouse strains capture the phenotypic diversity characteristic of human populations. J Appl Physiol. 2007 Jun;102(6):2369-78. Epub 2007 Feb 22. PubMed 17317875 MGI FullText

Paigen1 Data Protocol
Paigen B, Bouchard G, Carey MC Diet effects on gallstone formation and the assessment of liver morphology, plasma lipids, and atherosclerosis in 44 inbred strains of mice on high-fat atherogenic diet (not under pathogen-free conditions)

Paigen2 Data Protocol
Paigen B, Svenson KL, Peters LL Diet effects on plasma lipids and susceptibility to atherosclerosis in 43 inbred strains of mice on high-fat atherogenic diet (under pathogen-free conditions)

Paigen3 Data Protocol
Paigen B, Bouchard G, Carey MC Diet effects on gallstone formation, liver pathology, plasma lipids, and pathogen-accelerated atherosclerosis in 8 obesity mutant mouse strains

Bouchard G, Johnson D, Carver T, Paigen B, Carey MC. Cholesterol gallstone formation in overweight mice establishes that obesity per se is not linked directly to cholelithiasis risk. J Lipid Res. 2002 Jul;43(7):1105-13. PubMed 12091495 MGI FullText

Rusyn5 Data Protocol
Rusyn I Drug study: High-fat diet plus subchronic alcohol-induced effects in males of 14 inbred strains of mice

Tsuchiya M, Ji C, Kosyk O, Shymonyak S, Melnyk S, Kono H, Tryndyak V, Muskhelishvili L, Pogribny IP, Kaplowitz N, Rusyn I. Interstrain differences in liver injury and one-carbon metabolism in alcohol-fed mice. Hepatology. 2012 Jul;56(1):130-9. doi: 10.1002/hep.2564Epub 2012 Jun 6. PubMed 22307928 MGI FullText

Shockley1 Data Protocol
Shockley K, Paigen B, Churchill GA Diet effects on blood chemistry and lipids in 10 inbred strains of mice

Shockley KR, Witmer D, Burgess-Herbert SL, Paigen B, Churchill GA. Effects of atherogenic diet on hepatic gene expression across mouse strains. Physiol Genomics. 2009 Nov 6;39(3):172-82. Epub 2009 Aug 11. PubMed 19671657 MGI FullText

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