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Projects that involve: endocrine

Each of the projects below has phenotype data in MPD.
Links are available for data, protocols, and publications.

CGDpheno1     Data     Protocol    
Center for Genome Dynamics (CGD)     Multi-system survey of mouse physiology in 72 inbred strains of mice (ANOVA-adjusted methodology)


Cheverud1     Data     Protocol    
Cheverud JM     Diet-induced obesity and diabetes in 19 LGXSM recombinant inbred strains of mice
  Cheverud JM, Ehrich TH, Kenney JP, Pletscher LS, Semenkovich CF. Genetic evidence for discordance between obesity- and diabetes-related traits in the LGXSM recombinant inbred mouse strains. Diabetes. 2004 Oct;53(10):2700-8.     PubMed 15448104     MGI     FullText

Hrbek T, de Brito RA, Wang B, Pletscher LS, Cheverud JM. Genetic characterization of a new set of recombinant inbred lines (LGXSM) formed from the inter-cross of SM/J and LG/J inbred mouse strains. Mamm Genome. 2006 May;17(5):417-29.     PubMed 16688532     MGI     FullText



Deschepper1     Data     Protocol    
Deschepper CF, Gallo-Payet N     Systolic blood pressure and multi-organ morphologic characterization in 13 inbred strains of mice
  Deschepper CF, Olson JL, Otis M, Gallo-Payet N. Characterization of blood pressure and morphological traits in cardiovascular-related organs in 13 different inbred mouse strains. J Appl Physiol. 2004 Jul;97(1):369-76. Epub 2004 Mar 26.     PubMed 15047670     MGI     FullText



DiCurzio1     Data     Protocol    
Di Curzio DL, Goldowitz D     Adrenal gland weight and morphology in 66 BXD recombinant inbred strains of mice
  Di Curzio DL, Goldowitz D. The genetic basis of adrenal gland weight and structure in BXD recombinant inbred mice. Mamm Genome. 2011 Apr;22(3-4):209-34. Epub 2011 Feb 24.     PubMed 21347846     MGI     FullText

Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ. High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains. Genes Brain Behav. 2010 Mar 1;9(2):129-59. Epub 2009 Sep 22.     PubMed 19958391     MGI     FullText



Donahue1     Data     Protocol    
Donahue L     Bone mineral density, body composition, and craniofacial characterization in 30 inbred strains of mice
  Li R, Svenson KL, Donahue LR, Peters LL, Churchill GA. Relationships of dietary fat, body composition, and bone mineral density in inbred mouse strain panels. Physiol Genomics. 2008 Mar 14;33(1):26-32. Epub 2008 Jan 29.     PubMed 18230669     MGI     FullText



Jaxpheno3     Data     Protocol    
Jackson Laboratory     Blood chemistry survey of 11 inbred strains of mice


Naggert1     Data     Protocol    
Naggert J, Svenson KL, Smith RV, Paigen B, Peters LL     Diet effects on bone mineral density and content, body composition, and plasma glucose, leptin, and insulin levels in 43 inbred strains of mice on a high-fat atherogenic diet
  Li R, Svenson KL, Donahue LR, Peters LL, Churchill GA. Relationships of dietary fat, body composition, and bone mineral density in inbred mouse strain panels. Physiol Genomics. 2008 Mar 14;33(1):26-32. Epub 2008 Jan 29.     PubMed 18230669     MGI     FullText

Svenson KL, Von Smith R, Magnani PA, Suetin HR, Paigen B, Naggert JK, Li R, Churchill GA, Peters LL. Multiple trait measurements in 43 inbred mouse strains capture the phenotypic diversity characteristic of human populations. J Appl Physiol. 2007 Jun;102(6):2369-78. Epub 2007 Feb 22.     PubMed 17317875     MGI     FullText



Pletcher1     Data     Protocol    
Pletcher MT     Open field and tail suspension tests in males of 32 inbred strains of mice
  Miller BH, Schultz LE, Gulati A, Su AI, Pletcher MT. Phenotypic characterization of a genetically diverse panel of mice for behavioral despair and anxiety. PLoS One. 2010 Dec 29;5(12):e14458.     PubMed 21206921     MGI     FullText



Schonfeld1     Data     Protocol    
Schonfeld G     Strain survey of liver and plasma lipids and blood glucose levels in 11 inbred strains of mice
  Lin X, Yue P, Chen Z, Schonfeld G. Hepatic triglyceride contents are genetically determined in mice: results of a strain survey. Am J Physiol Gastrointest Liver Physiol. 2005 Jun;288(6):G1179-89. Epub 2004 Dec 9.     PubMed 15591160     MGI     FullText



Shockley1     Data     Protocol    
Shockley K, Paigen B, Churchill GA     Diet effects on blood chemistry and lipids in 10 inbred strains of mice
  Shockley KR, Witmer D, Burgess-Herbert SL, Paigen B, Churchill GA. Effects of atherogenic diet on hepatic gene expression across mouse strains. Physiol Genomics. 2009 Nov 6;39(3):172-82. Epub 2009 Aug 11.     PubMed 19671657     MGI     FullText



Yuan1     Data     Protocol    
Yuan R, Rosen CJ, Beamer WG     Aging study: IGF-1 and body weight for 33 inbred strains of mice
  Leduc MS, Hageman RS, Meng Q, Verdugo RA, Tsaih SW, Churchill GA, Paigen B, Yuan R. Identification of genetic determinants of IGF-1 levels and longevity among mouse inbred strains. Aging Cell. 2010 Oct;9(5):823-36. doi: 10.1111/j.1474-9726.2010.00612.x.     PubMed 20735370     MGI     FullText

Yuan R, Tsaih SW, Petkova SB, Marin de Evsikova C, Xing S, Marion MA, Bogue MA, Mills KD, Peters LL, Bult CJ, Rosen CJ, Sundberg JP, Harrison DE, Churchill GA, Paigen B. Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels. Aging Cell. 2009 Jun;8(3):277-87. Epub 2009 Apr 9.     PubMed 19627267     MGI     FullText



Yuan3     Data     Protocol    
Yuan R, Korstanje R     Aging study: Blood chemistry for 32 inbred strains of mice
  Sinke AP, Caputo C, Tsaih SW, Yuan R, Ren D, Deen PM, Korstanje R. Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulation. Physiol Genomics. 2011 Mar 16;43(5):265-70. Epub 2010 Dec 21.     PubMed 21177381     MGI     FullText



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