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Projects that involve: cardiovascular

Each of the projects below has phenotype data in MPD.
Links are available for data, protocols, and publications.

CGDpheno3     Data     Protocol    
Center for Genome Dynamics     Multi-system survey of mouse physiology in 8 inbred founder strains and 54 F1 hybrids of the Collaborative Cross
  Lenarcic AB, Svenson KL, Churchill GA, Valdar W. A general Bayesian approach to analyzing diallel crosses of inbred strains. Genetics. 2012 Feb;190(2):413-35.     PubMed 22345610     MGI     FullText



Chesler2     Data     Protocol    
Chesler EJ, Philip VM, Voy BH     Multi-system assessment of 8 inbred founder strains and 54 F1 hybrids of the Collaborative Cross
  Philip VM, Sokoloff G, Ackert-Bicknell CL, Striz M, Branstetter L, Beckmann MA, Spence JS, Jackson BL, Galloway LD, Barker P, Wymore AM, Hunsicker PR, Durtschi DC, Chesler EJ, et al. Genetic analysis in the Collaborative Cross breeding population. Genome Res. 2011 Aug;21(8):1223-38. Epub 2011 Jul 6.     PubMed 21734011     MGI     FullText



Chesler3     Data     Protocol    
Chesler EJ, Philip VM, Voy BH     Multi-system assessment of 8 inbred founder strains and 380+ emerging lines (pre-CC) of the Collaborative Cross
  Philip VM, Sokoloff G, Ackert-Bicknell CL, Striz M, Branstetter L, Beckmann MA, Spence JS, Jackson BL, Galloway LD, Barker P, Wymore AM, Hunsicker PR, Durtschi DC, Chesler EJ, et al. Genetic analysis in the Collaborative Cross breeding population. Genome Res. 2011 Aug;21(8):1223-38. Epub 2011 Jul 6.     PubMed 21734011     MGI     FullText



Cheverud1     Data     Protocol    
Cheverud JM     Diet-induced obesity and diabetes in 19 LGXSM recombinant inbred strains of mice
  Cheverud JM, Ehrich TH, Kenney JP, Pletscher LS, Semenkovich CF. Genetic evidence for discordance between obesity- and diabetes-related traits in the LGXSM recombinant inbred mouse strains. Diabetes. 2004 Oct;53(10):2700-8.     PubMed 15448104     MGI     FullText

Hrbek T, de Brito RA, Wang B, Pletscher LS, Cheverud JM. Genetic characterization of a new set of recombinant inbred lines (LGXSM) formed from the inter-cross of SM/J and LG/J inbred mouse strains. Mamm Genome. 2006 May;17(5):417-29.     PubMed 16688532     MGI     FullText



Deschepper1     Data     Protocol    
Deschepper CF, Gallo-Payet N     Systolic blood pressure and multi-organ morphologic characterization in 13 inbred strains of mice
  Deschepper CF, Olson JL, Otis M, Gallo-Payet N. Characterization of blood pressure and morphological traits in cardiovascular-related organs in 13 different inbred mouse strains. J Appl Physiol. 2004 Jul;97(1):369-76. Epub 2004 Mar 26.     PubMed 15047670     MGI     FullText



Eumorphia6     Data     Protocol    
Eumorphia / Europhenome     Echocardiographic parameters in 4 inbred strains of mice


Gavras1     Data     Protocol    
Gavras H, Johns C, Paigen B, Peters LL     Diet effects: salt-induced changes in blood pressure and heart rate in 11 inbred strains of mice


Hampton1     Data     Protocol    
Hampton TG, Paigen B, Seburn KL     Electrocardiography in 17 inbred strains of mice


Jaxpheno2     Data     Protocol    
Jackson Laboratory     Morphometric (organ weight) survey of 11 inbred strains of mice


Jaxpheno8     Data     Protocol    
Jackson Laboratory     Echocardiography and auditory brainstem response survey in males of 7 inbred strains of mice


Jaxwest1     Data     Protocol    
Jackson Laboratory     Multi-system analysis of physiology on 7 inbred strains of mice


Lake1     Data     Protocol    
Lake J, Donahue L, Davisson MT     Multi-system analysis of mouse physiology, C57BL/6J-Chr#A/J/NaJ chromosome substitution panel


Maurer1     Data     Protocol    
Maurer F, Beckmann J, Abriel H, Pedrazzini T     Drug study: Cardiovascular response to beta-adrenergic blockade or activation in males of 23 inbred strains of mice
  Berthonneche C, Peter B, Schüpfer F, Hayoz P, Kutalik Z, Abriel H, Pedrazzini T, Beckmann JS, Bergmann S, Maurer F. Cardiovascular response to beta-adrenergic blockade or activation in 23 inbred mouse strains. PLoS One. 2009 Aug 12;4(8):e6610.     PubMed 19672458     MGI     FullText



Paigen1     Data     Protocol    
Paigen B, Bouchard G, Carey MC     Diet effects on gallstone formation and the assessment of liver morphology, plasma lipids, and atherosclerosis in 44 inbred strains of mice on high-fat atherogenic diet (not under pathogen-free conditions)


Paigen2     Data     Protocol    
Paigen B, Svenson KL, Peters LL     Diet effects on plasma lipids and susceptibility to atherosclerosis in 43 inbred strains of mice on high-fat atherogenic diet (under pathogen-free conditions)
  Svenson KL, Von Smith R, Magnani PA, Suetin HR, Paigen B, Naggert JK, Li R, Churchill GA, Peters LL. Multiple trait measurements in 43 inbred mouse strains capture the phenotypic diversity characteristic of human populations. J Appl Physiol. 2007 Jun;102(6):2369-78. Epub 2007 Feb 22.     PubMed 17317875     MGI     FullText



Paigen3     Data     Protocol    
Paigen B, Bouchard G, Carey MC     Diet effects on gallstone formation, liver pathology, plasma lipids, and pathogen-accelerated atherosclerosis in 8 obesity mutant mouse strains
  Bouchard G, Johnson D, Carver T, Paigen B, Carey MC. Cholesterol gallstone formation in overweight mice establishes that obesity per se is not linked directly to cholelithiasis risk. J Lipid Res. 2002 Jul;43(7):1105-13.     PubMed 12091495     MGI     FullText



Reed1     Data     Protocol    
Reed DR, Bachmanov AA, Tordoff MG     Survey of adipose depots, body size, and heart and kidney weights in males of 28 inbred strains of mice


Sugiyama1     Data     Protocol    
Sugiyama F, Tsukahara C, Paigen B     Blood pressure survey in males of 25 inbred strains of mice
  Tsukahara C, Sugiyama F, Paigen B, Kunita S, Yagami K. Blood pressure in 15 inbred mouse strains and its lack of relation with obesity and insulin resistance in the progeny of an NZO/HILtJ x C3H/HeJ intercross. Mamm Genome. 2004 Dec;15(12):943-50.     PubMed 15599552     MGI     FullText



Svenson1     Data     Protocol    
Svenson KL, Smith RV     Systolic blood pressure and pulse rate survey in 14 inbred strains of mice


Xing1     Data     Protocol    
Xing S, Korstanje R, Paigen B     Aging study: Electrocardiogram for 29 inbred strains of mice
  Xing S, Tsaih SW, Yuan R, Svenson KL, Jorgenson LM, So M, Paigen BJ, Korstanje R. Genetic influence on electrocardiogram time intervals and heart rate in aging mice. Am J Physiol Heart Circ Physiol. 2009 Jun;296(6):H1907-13. Epub 2009 Apr 24.     PubMed 19395551     MGI     FullText



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