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Projects that involve: cardiovascular
Each of the projects below has phenotype data in MPD.
Links are available for data, protocols, and publications.
View several projects together
CGDpheno3
Data
Protocol
Center for Genome Dynamics Multi-system survey of mouse physiology in 8 inbred founder strains and 54 F1 hybrids of the Collaborative Cross
Lenarcic AB, Svenson KL, Churchill GA, Valdar W. A general Bayesian approach to analyzing diallel crosses of inbred strains. Genetics. 2012 Feb;190(2):413-35.
PubMed 22345610
MGI
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Chesler2
Data
Protocol
Chesler EJ, Philip VM, Voy BH Multi-system assessment of 8 inbred founder strains and 54 F1 hybrids of the Collaborative Cross
Philip VM, Sokoloff G, Ackert-Bicknell CL, Striz M, Branstetter L, Beckmann MA, Spence JS, Jackson BL, Galloway LD, Barker P, Wymore AM, Hunsicker PR, Durtschi DC, Chesler EJ, et al. Genetic analysis in the Collaborative Cross breeding population. Genome Res. 2011 Aug;21(8):1223-38. Epub 2011 Jul 6.
PubMed 21734011
MGI
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Chesler3
Data
Protocol
Chesler EJ, Philip VM, Voy BH Multi-system assessment of 8 inbred founder strains and 380+ emerging lines (pre-CC) of the Collaborative Cross
Philip VM, Sokoloff G, Ackert-Bicknell CL, Striz M, Branstetter L, Beckmann MA, Spence JS, Jackson BL, Galloway LD, Barker P, Wymore AM, Hunsicker PR, Durtschi DC, Chesler EJ, et al. Genetic analysis in the Collaborative Cross breeding population. Genome Res. 2011 Aug;21(8):1223-38. Epub 2011 Jul 6.
PubMed 21734011
MGI
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Cheverud1
Data
Protocol
Cheverud JM Diet-induced obesity and diabetes in 19 LGXSM recombinant inbred strains of mice
Cheverud JM, Ehrich TH, Kenney JP, Pletscher LS, Semenkovich CF. Genetic evidence for discordance between obesity- and diabetes-related traits in the LGXSM recombinant inbred mouse strains. Diabetes. 2004 Oct;53(10):2700-8.
PubMed 15448104
MGI
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Hrbek T, de Brito RA, Wang B, Pletscher LS, Cheverud JM. Genetic characterization of a new set of recombinant inbred lines (LGXSM) formed from the inter-cross of SM/J and LG/J inbred mouse strains. Mamm Genome. 2006 May;17(5):417-29.
PubMed 16688532
MGI
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Deschepper1
Data
Protocol
Deschepper CF, Gallo-Payet N Systolic blood pressure and multi-organ morphologic characterization in 13 inbred strains of mice
Deschepper CF, Olson JL, Otis M, Gallo-Payet N. Characterization of blood pressure and morphological traits in cardiovascular-related organs in 13 different inbred mouse strains. J Appl Physiol. 2004 Jul;97(1):369-76. Epub 2004 Mar 26.
PubMed 15047670
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Eumorphia6
Data
Protocol
Eumorphia / Europhenome Echocardiographic parameters in 4 inbred strains of mice
Gavras1
Data
Protocol
Gavras H, Johns C, Paigen B, Peters LL Diet effects: salt-induced changes in blood pressure and heart rate in 11 inbred strains of mice
Hampton1
Data
Protocol
Hampton TG, Paigen B, Seburn KL Electrocardiography in 17 inbred strains of mice
Jaxpheno2
Data
Protocol
Jackson Laboratory Morphometric (organ weight) survey of 11 inbred strains of mice
Jaxpheno8
Data
Protocol
Jackson Laboratory Echocardiography and auditory brainstem response survey in males of 7 inbred strains of mice
Jaxwest1
Data
Protocol
Jackson Laboratory Multi-system analysis of physiology on 7 inbred strains of mice
Lake1
Data
Protocol
Lake J, Donahue L, Davisson MT Multi-system analysis of mouse physiology, C57BL/6J-Chr#
A/J
/NaJ chromosome substitution panel
Maurer1
Data
Protocol
Maurer F, Beckmann J, Abriel H, Pedrazzini T Drug study: Cardiovascular response to beta-adrenergic blockade or activation in males of 23 inbred strains of mice
Berthonneche C, Peter B, Schüpfer F, Hayoz P, Kutalik Z, Abriel H, Pedrazzini T, Beckmann JS, Bergmann S, Maurer F. Cardiovascular response to beta-adrenergic blockade or activation in 23 inbred mouse strains. PLoS One. 2009 Aug 12;4(8):e6610.
PubMed 19672458
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Paigen1
Data
Protocol
Paigen B, Bouchard G, Carey MC Diet effects on gallstone formation and the assessment of liver morphology, plasma lipids, and atherosclerosis in 44 inbred strains of mice on high-fat atherogenic diet (not under pathogen-free conditions)
Paigen2
Data
Protocol
Paigen B, Svenson KL, Peters LL Diet effects on plasma lipids and susceptibility to atherosclerosis in 43 inbred strains of mice on high-fat atherogenic diet (under pathogen-free conditions)
Svenson KL, Von Smith R, Magnani PA, Suetin HR, Paigen B, Naggert JK, Li R, Churchill GA, Peters LL. Multiple trait measurements in 43 inbred mouse strains capture the phenotypic diversity characteristic of human populations. J Appl Physiol. 2007 Jun;102(6):2369-78. Epub 2007 Feb 22.
PubMed 17317875
MGI
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Paigen3
Data
Protocol
Paigen B, Bouchard G, Carey MC Diet effects on gallstone formation, liver pathology, plasma lipids, and pathogen-accelerated atherosclerosis in 8 obesity mutant mouse strains
Bouchard G, Johnson D, Carver T, Paigen B, Carey MC. Cholesterol gallstone formation in overweight mice establishes that obesity per se is not linked directly to cholelithiasis risk. J Lipid Res. 2002 Jul;43(7):1105-13.
PubMed 12091495
MGI
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Reed1
Data
Protocol
Reed DR, Bachmanov AA, Tordoff MG Survey of adipose depots, body size, and heart and kidney weights in males of 28 inbred strains of mice
Sugiyama1
Data
Protocol
Sugiyama F, Tsukahara C, Paigen B Blood pressure survey in males of 25 inbred strains of mice
Tsukahara C, Sugiyama F, Paigen B, Kunita S, Yagami K. Blood pressure in 15 inbred mouse strains and its lack of relation with obesity and insulin resistance in the progeny of an NZO/HILtJ x C3H/HeJ intercross. Mamm Genome. 2004 Dec;15(12):943-50.
PubMed 15599552
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Svenson1
Data
Protocol
Svenson KL, Smith RV Systolic blood pressure and pulse rate survey in 14 inbred strains of mice
Xing1
Data
Protocol
Xing S, Korstanje R, Paigen B Aging study: Electrocardiogram for 29 inbred strains of mice
Xing S, Tsaih SW, Yuan R, Svenson KL, Jorgenson LM, So M, Paigen BJ, Korstanje R. Genetic influence on electrocardiogram time intervals and heart rate in aging mice. Am J Physiol Heart Circ Physiol. 2009 Jun;296(6):H1907-13. Epub 2009 Apr 24.
PubMed 19395551
MGI
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