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Projects that involve: brain

Each of the projects below has phenotype data in MPD.
Links are available for data, protocols, and publications.

Chesler3     Data     Protocol    
Chesler EJ, Philip VM, Voy BH     Multi-system assessment of 8 inbred founder strains and 380+ emerging lines (pre-CC) of the Collaborative Cross
  Philip VM, Sokoloff G, Ackert-Bicknell CL, Striz M, Branstetter L, Beckmann MA, Spence JS, Jackson BL, Galloway LD, Barker P, Wymore AM, Hunsicker PR, Durtschi DC, Chesler EJ, et al. Genetic analysis in the Collaborative Cross breeding population. Genome Res. 2011 Aug;21(8):1223-38. Epub 2011 Jul 6.     PubMed 21734011     MGI     FullText



Crabbe2     Data     Protocol    
Crabbe JC, Gallaher EJ, Belknap JK     Drug study: Effects of diazepam on activity, motor coordination, and body temperature, in 15 inbred strains of mice
  Crabbe JC, Gallaher EJ, Cross SJ, Belknap JK. Genetic determinants of sensitivity to diazepam in inbred mice. Behav Neurosci. 1998 Jun;112(3):668-77.     PubMed 9676982     MGI     FullText



Frankel1     Data     Protocol    
Frankel WN, White HS     Drug study: Induced seizures and their suppression with lamotrigine in 16 inbred strains of mice
  Frankel WN, Taylor L, Beyer B, Tempel BL, White HS. Electroconvulsive thresholds of inbred mouse strains. Genomics. 2001 Jun 15;74(3):306-12.     PubMed 11414758     MGI     FullText



Gould1     Data     Protocol    
Can A, Gould TD     Drug study: Antidepressant-like responses to lithium in males of 8 inbred mouse strains and 3 outbred stocks
  Can A, Blackwell RA, Piantadosi SC, Dao DT, O'Donnell KC, Gould TD. Antidepressant-like responses to lithium in genetically diverse mouse strains. Genes Brain Behav. 2011 Jun;10(4):434-43. doi: 10.1111/j.1601-183X.2011.00682.x. Epub 2011 Mar 1.     PubMed 21306560     MGI     FullText



Jaxpheno2     Data     Protocol    
Jackson Laboratory     Morphometric (organ weight) survey of 11 inbred strains of mice


Marchuk1     Data     Protocol    
Marchuk DA     Surgically-induced cerebral infarct volume for assessing stroke susceptibility in 16 inbred strains of mice
  Keum S, Marchuk DA. A locus mapping to mouse chromosome 7 determines infarct volume in a mouse model of ischemic stroke. Circ Cardiovasc Genet. 2009 Dec;2(6):591-8. Epub 2009 Oct 19.     PubMed 20031639     MGI     FullText



Richfield1     Data     Protocol    
Richfield EK, Mhyre TR, Cory-Slechta DA, Thiruchelvam M, Chesler EJ     Behavioral, neurochemical, neuroanatomical, and neurotoxicological survey of the midbrain dopamine system in males of 15 inbred strains of mice
  Mhyre TR, Chesler EJ, Thiruchelvam M, Lungu C, Cory-Slechta DA, Fry JD, Richfield EK. Heritability, correlations and in silico mapping of locomotor behavior and neurochemistry in inbred strains of mice. Genes Brain Behav. 2005 Jun;4(4):209-28.     PubMed 15924554     MGI     FullText



Wahlsten1     Data     Protocol    
Wahlsten D, Crabbe JC     Survey of motor activity, behavior, and forebrain morphometry in 21 inbred strains of mice across two laboratories
  Wahlsten D, Bachmanov A, Finn DA, Crabbe JC. Stability of inbred mouse strain differences in behavior and brain size between laboratories and across decades. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16364-9. Epub 2006 Oct 19.     PubMed 17053075     MGI     FullText

Wahlsten D, Metten P, Crabbe JC. Survey of 21 inbred mouse strains in two laboratories reveals that BTBR T/+ tf/tf has severely reduced hippocampal commissure and absent corpus callosum. Brain Res. 2003 May 2;971(1):47-54.     PubMed 12691836     MGI     FullText



Wiltshire3     Data     Protocol    
Wiltshire T, Pletcher MT     Drug study: Neurobiochemical analytes in response to chronic fluoxetine treatment in males of 30 inbred mouse strains
  Benton CS, Miller BH, Skwerer S, Suzuki O, Schultz LE, Cameron MD, Marron JS, Pletcher MT, Wiltshire T. Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. Psychopharmacology (Berl). 2012 May;221(2):297-315. Epub 2011 Nov 24.     PubMed 22113448     MGI     FullText



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