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Projects that involve: brain
Each of the projects below has phenotype data in MPD.
Links are available for data, protocols, and publications.
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Chesler3
Data
Protocol
Chesler EJ, Philip VM, Voy BH Multi-system assessment of 8 inbred founder strains and 380+ emerging lines (pre-CC) of the Collaborative Cross
Philip VM, Sokoloff G, Ackert-Bicknell CL, Striz M, Branstetter L, Beckmann MA, Spence JS, Jackson BL, Galloway LD, Barker P, Wymore AM, Hunsicker PR, Durtschi DC, Chesler EJ, et al. Genetic analysis in the Collaborative Cross breeding population. Genome Res. 2011 Aug;21(8):1223-38. Epub 2011 Jul 6.
PubMed 21734011
MGI
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Crabbe2
Data
Protocol
Crabbe JC, Gallaher EJ, Belknap JK Drug study: Effects of diazepam on activity, motor coordination, and body temperature, in 15 inbred strains of mice
Crabbe JC, Gallaher EJ, Cross SJ, Belknap JK. Genetic determinants of sensitivity to diazepam in inbred mice. Behav Neurosci. 1998 Jun;112(3):668-77.
PubMed 9676982
MGI
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Frankel1
Data
Protocol
Frankel WN, White HS Drug study: Induced seizures and their suppression with lamotrigine in 16 inbred strains of mice
Frankel WN, Taylor L, Beyer B, Tempel BL, White HS. Electroconvulsive thresholds of inbred mouse strains. Genomics. 2001 Jun 15;74(3):306-12.
PubMed 11414758
MGI
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Gould1
Data
Protocol
Can A, Gould TD Drug study: Antidepressant-like responses to lithium in males of 8 inbred mouse strains and 3 outbred stocks
Can A, Blackwell RA, Piantadosi SC, Dao DT, O'Donnell KC, Gould TD. Antidepressant-like responses to lithium in genetically diverse mouse strains. Genes Brain Behav. 2011 Jun;10(4):434-43. doi: 10.1111/j.1601-183X.2011.00682.x. Epub 2011 Mar 1.
PubMed 21306560
MGI
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Jaxpheno2
Data
Protocol
Jackson Laboratory Morphometric (organ weight) survey of 11 inbred strains of mice
Marchuk1
Data
Protocol
Marchuk DA Surgically-induced cerebral infarct volume for assessing stroke susceptibility in 16 inbred strains of mice
Keum S, Marchuk DA. A locus mapping to mouse chromosome 7 determines infarct volume in a mouse model of ischemic stroke. Circ Cardiovasc Genet. 2009 Dec;2(6):591-8. Epub 2009 Oct 19.
PubMed 20031639
MGI
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Richfield1
Data
Protocol
Richfield EK, Mhyre TR, Cory-Slechta DA, Thiruchelvam M, Chesler EJ Behavioral, neurochemical, neuroanatomical, and neurotoxicological survey of the midbrain dopamine system in males of 15 inbred strains of mice
Mhyre TR, Chesler EJ, Thiruchelvam M, Lungu C, Cory-Slechta DA, Fry JD, Richfield EK. Heritability, correlations and in silico mapping of locomotor behavior and neurochemistry in inbred strains of mice. Genes Brain Behav. 2005 Jun;4(4):209-28.
PubMed 15924554
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Wahlsten1
Data
Protocol
Wahlsten D, Crabbe JC Survey of motor activity, behavior, and forebrain morphometry in 21 inbred strains of mice across two laboratories
Wahlsten D, Bachmanov A, Finn DA, Crabbe JC. Stability of inbred mouse strain differences in behavior and brain size between laboratories and across decades. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16364-9. Epub 2006 Oct 19.
PubMed 17053075
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Wahlsten D, Metten P, Crabbe JC. Survey of 21 inbred mouse strains in two laboratories reveals that BTBR T/+ tf/tf has severely reduced hippocampal commissure and absent corpus callosum. Brain Res. 2003 May 2;971(1):47-54.
PubMed 12691836
MGI
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Wiltshire3
Data
Protocol
Wiltshire T, Pletcher MT Drug study: Neurobiochemical analytes in response to chronic fluoxetine treatment in males of 30 inbred mouse strains
Benton CS, Miller BH, Skwerer S, Suzuki O, Schultz LE, Cameron MD, Marron JS, Pletcher MT, Wiltshire T. Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. Psychopharmacology (Berl). 2012 May;221(2):297-315. Epub 2011 Nov 24.
PubMed 22113448
MGI
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