MPD - Projects that involve: blood

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Projects that involve: blood–lipids

Each of the projects below has phenotype data in MPD.
Links are available for data, protocols, and publications.

Albers1 Data Protocol
Albers JJ, Paigen B Diet-induced changes in plasma phospholipid transfer protein activity, lipids, and lipoproteins in 15 inbred strains of mice

Albers JJ, Pitman W, Wolfbauer G, Cheung MC, Kennedy H, Tu AY, Marcovina SM, Paigen B. Relationship between phospholipid transfer protein activity and HDL level and size among inbred mouse strains. J Lipid Res. 1999 Feb;40(2):295-301. PubMed 9925659 MGI FullText

CGDpheno1 Data Protocol
Center for Genome Dynamics (CGD) Multi-system survey of mouse physiology in 72 inbred strains of mice (ANOVA-adjusted methodology)

CGDpheno3 Data Protocol
Center for Genome Dynamics Multi-system survey of mouse physiology in 8 inbred founder strains and 54 F1 hybrids of the Collaborative Cross

Lenarcic AB, Svenson KL, Churchill GA, Valdar W. A general Bayesian approach to analyzing diallel crosses of inbred strains. Genetics. 2012 Feb;190(2):413-35. PubMed 22345610 MGI FullText

Cheverud1 Data Protocol
Cheverud JM Diet-induced obesity and diabetes in 19 LGXSM recombinant inbred strains of mice

Cheverud JM, Ehrich TH, Kenney JP, Pletscher LS, Semenkovich CF. Genetic evidence for discordance between obesity- and diabetes-related traits in the LGXSM recombinant inbred mouse strains. Diabetes. 2004 Oct;53(10):2700-8. PubMed 15448104 MGI FullText

Hrbek T, de Brito RA, Wang B, Pletscher LS, Cheverud JM. Genetic characterization of a new set of recombinant inbred lines (LGXSM) formed from the inter-cross of SM/J and LG/J inbred mouse strains. Mamm Genome. 2006 May;17(5):417-29. PubMed 16688532 MGI FullText

Eumorphia1 Data Protocol
Eumorphia / Europhenome Blood chemistry and hematology in 8 inbred strains of mice

Champy MF, Selloum M, Zeitler V, Caradec C, Jung B, Rousseau S, Pouilly L, Sorg T, Auwerx J. Genetic background determines metabolic phenotypes in the mouse. Mamm Genome. 2008 May;19(5):318-3Epub 2008 Apr 5. PubMed 18392653 MGI FullText

HMDPpheno2 Data Protocol
Bennett BJ, Farber CR, Orozco L, Eskin E, Lusis AJ Plasma lipids and body composition in males of 99 strains of mice in the Hybrid Mouse Diversity Panel (HMDP)

Bennett BJ, Farber CR, Orozco L, Kang HM, Ghazalpour A, Siemers N, Neubauer M, Neuhaus I, Yordanova R, Guan B, Truong A, Yang WP, He A, Kayne P, Gargalovic P, Kirchgessner T, Pan C, Castellani LW, Kostem E, Furlotte N, Drake TA, Eskin E, Lusis AJ. A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Res. 2010 Feb;20(2):281-90. Epub 2010 Jan 6. PubMed 20054062 MGI FullText

Jaxpheno3 Data Protocol
Jackson Laboratory Blood chemistry survey of 11 inbred strains of mice

Lake1 Data Protocol
Lake J, Donahue L, Davisson MT Multi-system analysis of mouse physiology, C57BL/6J-Chr#^A/J/NaJ chromosome substitution panel

Paigen1 Data Protocol
Paigen B, Bouchard G, Carey MC Diet effects on gallstone formation and the assessment of liver morphology, plasma lipids, and atherosclerosis in 44 inbred strains of mice on high-fat atherogenic diet (not under pathogen-free conditions)

Paigen2 Data Protocol
Paigen B, Svenson KL, Peters LL Diet effects on plasma lipids and susceptibility to atherosclerosis in 43 inbred strains of mice on high-fat atherogenic diet (under pathogen-free conditions)

Svenson KL, Von Smith R, Magnani PA, Suetin HR, Paigen B, Naggert JK, Li R, Churchill GA, Peters LL. Multiple trait measurements in 43 inbred mouse strains capture the phenotypic diversity characteristic of human populations. J Appl Physiol. 2007 Jun;102(6):2369-78. Epub 2007 Feb 22. PubMed 17317875 MGI FullText

Paigen3 Data Protocol
Paigen B, Bouchard G, Carey MC Diet effects on gallstone formation, liver pathology, plasma lipids, and pathogen-accelerated atherosclerosis in 8 obesity mutant mouse strains

Bouchard G, Johnson D, Carver T, Paigen B, Carey MC. Cholesterol gallstone formation in overweight mice establishes that obesity per se is not linked directly to cholelithiasis risk. J Lipid Res. 2002 Jul;43(7):1105-13. PubMed 12091495 MGI FullText

Paigen4 Data Protocol
Paigen B, Svenson KL, Peters LL Diet effects: Survey of plasma lipids in 43 inbred strains of mice fed standard maintenance diet (6% fat)

RIKEN-EAD1 Data Protocol
RIKEN BioResource Center / Experimental Animal Division Blood chemistry, hematology, and body size for 56 inbred mouse strains (RBRC)

RIKEN-EAD2 Data Protocol
RIKEN BioResource Center / Experimental Animal Division Blood chemistry, hematology, and body size for 33 RBRC wild-derived mouse strains

Schonfeld1 Data Protocol
Schonfeld G Strain survey of liver and plasma lipids and blood glucose levels in 11 inbred strains of mice

Lin X, Yue P, Chen Z, Schonfeld G. Hepatic triglyceride contents are genetically determined in mice: results of a strain survey. Am J Physiol Gastrointest Liver Physiol. 2005 Jun;288(6):G1179-89. Epub 2004 Dec 9. PubMed 15591160 MGI FullText

Shockley1 Data Protocol
Shockley K, Paigen B, Churchill GA Diet effects on blood chemistry and lipids in 10 inbred strains of mice

Shockley KR, Witmer D, Burgess-Herbert SL, Paigen B, Churchill GA. Effects of atherogenic diet on hepatic gene expression across mouse strains. Physiol Genomics. 2009 Nov 6;39(3):172-82. Epub 2009 Aug 11. PubMed 19671657 MGI FullText

Svenson3 Data Protocol
Svenson KL, Forejt J, Donahue L, Paigen B Hematology and blood chemistry of C57BL/6J-Chr#^PWD/Ph/ForeJ mouse chromosome substitution strains

Gregorová S, Divina P, Storchova R, Trachtulec Z, Fotopulosova V, Svenson KL, Donahue LR, Paigen B, Forejt J. Mouse consomic strains: exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies. Genome Res. 2008 Mar;18(3):509-15. Epub 2008 Feb 6. PubMed 18256238 MGI FullText

Yuan3 Data Protocol
Yuan R, Korstanje R Aging study: Blood chemistry for 32 inbred strains of mice

Sinke AP, Caputo C, Tsaih SW, Yuan R, Ren D, Deen PM, Korstanje R. Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulation. Physiol Genomics. 2011 Mar 16;43(5):265-70. Epub 2010 Dec 21. PubMed 21177381 MGI FullText

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