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Data set / project: Gatti2   (2014)

Project QTL mapping of neutrophil counts in Diversity Outbred population

Gatti2     MPD:289     2014     QTLA: Gatti_2014

AfilliationChurchill Group QTL Archive
Investigators Daniel M Gatti     The Jackson Laboratory   Bar Harbor, ME
Contact Daniel M Gatti
Other participants Svenson KL, Shabalin A, Wu L, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman K, Churchill GA
  Mapping of neutrophil counts in whole blood using 742 JAX Diversity Outbred mice (410 female, 332 male). Males (1025 +/- 427, mean +/- s.d.) had higher mean neutrophil counts than females (838 +/- 422). The trait has an estimated heritability of 0.132.
 Available download files:
Excel file with descriptions and data: • Data_Description_Gatti_2014.xlsx
CSV files • Gatti_2014_geno.csv
• Gatti_2014_pheno.csv
Large zipped data sets / archives •
Progenitors: CC8 founder strains         Cross type: Diversity Outbred
Population size: 410     332    

Studied phenotypes
WBC   white blood cell counts [thousands/µL] age 10-12wks  
NEUR   neutrophil counts [n/µL] age 10-12wks  
Ontology term mappings

Phenotyping methodologies utilized:   • complete blood count    

Notes and
This work was supported in part by National Institutes of Health grants P50 GM076468 and R01 GM070683 (to GAC), R01 GM074244 (to KWB) and RC1DK087346, DK076050, DK056350 (to DP).
Changelog No updates or corrections have been posted since initial release in Apr 2014
Relocated to MPD from in Feb 2015.

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