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Project data set: Palmer1   (2007)

Project Survey of innate anxiety-like behavior and fear conditioning in C57BL/6J-Chr#A/J/NaJ mouse chromosome substitution panel (19 strains)

MPD:255     2007     Palmer1     Citing

Investigators Abraham Palmer     University of Chicago   Chicago, IL
Christine A Ponder     Rockefeller University   New York, NY
Michealanne Munoz     University of Chicago   Chicago, IL
T Conrad Gilliam     University of Chicago   Chicago, IL
Web site Investigator's lab
Contact Abraham Palmer       aap@uchicago.edu
Introductory
description
An investigation of fear-conditioned behavior during re-exposure to a specific context and tone.
Study design

Study design: baseline survey; 1 cohort.
19 strains tested     female male     Test age: 7-12wks

Availability
Strain survey data and protocol available – click here to view
Changelog There have been no updates or corrections to the data set since MPD release in Sep 2007  
Notes and
funding
Funding provided by NIH MH70933, GM07088; National Alliance for Research on Schizophrenia and Depression (NARSAD) Young Investigator Award

Reference
Ponder CA, Munoz M, Gilliam TC, Palmer AA. Genetic architecture of fear conditioning in chromosome substitution strains: relationship to measures of innate (unlearned) anxiety-like behavior. Mamm Genome. 2007 Apr;18(4):221-8. Epub 2007 May 10.     PubMed 17492333     MGI


Related papers
Ponder CA, Kliethermes CL, Drew MR, Muller J, Das K, Risbrough VB, Crabbe JC, Gilliam TC, Palmer AA. Selection for contextual fear conditioning affects anxiety-like behaviors and gene expression. Genes Brain Behav. 2007 Nov;6(8):736-49. Epub 2007 Feb 16.     PubMed 17309658     MGI

Sokoloff G, Parker CC, Lim JE, Palmer AA. Anxiety and fear in a cross of C57BL/6J and DBA/2J mice: mapping overlapping and independent QTL for related traits. Genes Brain Behav. 2011 Jul;10(5):604-14. doi: 10.1111/j.1601-183X.2011.00699.x. Epub 2011 May 31.     PubMed 21554534     MGI

Winawer MR, Kuperman R, Niethammer M, Sherman S, Rabinowitz D, Guell IP, Ponder CA, Palmer AA. Use of chromosome substitution strains to identify seizure susceptibility loci in mice. Mamm Genome. 2007 Jan;18(1):23-31. Epub 2007 Jan 22.     PubMed 17242861     MGI

 




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