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Tordoff1 project protocol

Tordoff MG, Bachmanov AA

Diet preference: Survey of salt preference in drinking water for males of 28 inbred strains of mice

Taste preferences between two fluid sources were measured:
  • NaCl solution vs. water, using concentrations of 75, 150, 300, and 450 mM
  • KCl solution vs. water, using concentrations of 10, 30, 100, 200, and 300 mM
  • CaCl2 solution vs. water, using concentrations of 3, 10, 30, and 100 mM
  • NH4Cl solution vs. water, using concentrations of 10, 30, 100 and 300 mM
For each solution and concentration, intake was measured over a 48h period, and preference ratios (solution vs. water) computed. These preference ratios (%) are presented as MPD measurements.

Study design: baseline survey; 1 cohort.
28 strains tested     male only     Test age: 4-12wks

Tordoff1 project data page       Animals and environment

 

 

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