Vendor |
Ten
inbred
strains
of
mice
of
both
genders
were
purchased
from
Jackson
Laboratory
(JAX®,
Bar
Harbor,
ME).
AKR
males
were
not
studied
because
only
AKR
females
were
available
from
the
supplier. |
Ages
|
Mice
were
11-12
wks
of
age
on
the
day
of
sacrifice |
Feed
|
Purina
mouse
chow
5053
containing
4.5%
fat,
20.0%
protein,
and
54.8%
carbohydrate
(LabDiet)
|
Water
|
Ad
libitum
|
Housing
|
group-housed
4-5
mice
of
the
same
sex
per
cage |
Room
temperature |
24°C |
Bedding |
corncob;
aspen
chips
during
GTT
and
ITT
days |
Photoperiod |
12h/12h
light/dark
cycle
(6:00
AM
to
6:00
PM) |
Health
status
|
All
animal
procedures
were
performed
in
accordance
with
guidelines
of
Washington
University's
Animal
Studies
Committee
and
approved
by
the
IACUC
of
Washington
University. |
