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Johnson1 project protocol

Johnson KR, Erway LC, Zheng QY

Assessment of age-dependent hearing loss in 51 inbred strains of mice

Four ABR threshold measurements were taken per mouse, in response to four different audible sounds. The first measurement was for a click; the second for an 8kHz pip; the third for a 16kHz pip; the fourth for a 32kHz pip. The results are presented here broken down by mouse age. Early onset of hearing impairment occurs at age < 13 weeks. Later onset of hearing impairment occurs at age ≥ 13 weeks.

Study design: baseline survey; 2 cohorts.
51 strains tested     female male     Test age: 3-12wks and 15-72wks

Johnson1 project data page       Animals and environment

 

 

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