Crabbe JC, Wahlsten D
with Metten P, Yu C-H, Schlumbohm JP, Cameron AJ
Drug study: Evaluation of ethanol sensitivity and intoxication using motor incoordination in the balance beam and grid test, in 8 inbred strains of mice
An investigation of the genetic determinants of ethanol sensitivity and intoxication. Animals were assayed for motor and/or behavioral incoordination following saline administration in control vs. ethanol treated mice using balance beam and grid test apparatus. Four i.p. treatment group cohorts: (1) saline; (2) ethanol 1.0 mg/kg body weight; (3) ethanol 1.2 mg/kg; (4) ethanol 1.4 mg/kg.
Study design:
control vs. intervention in various doses;
4 cohorts.
8 strains tested
Test age:
8-16wks
Test age:
8-16wks
