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Project data set: Yuan1   (2007)

Project Aging study: IGF-1 and body weight for 33 inbred strains of mice

Animals were evaluated for serum IGF-1 levels using radioimmunoassay.

Study design: aging study (longitudinal); 1 cohort.
33 strains tested     female male     Test age: 6, 12, 18 mo

Investigators Yuan R, Rosen CJ, Beamer WG   [Details, papers]
The Jackson Laboratory Nathan Shock Center

Protocol View phenotyping protocol and methods

Yuan1
measurements



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          Ontologies


body weight         scales  
Yuan1
body weight [g]  
      • 6mo  • 12mo  • 18mo    • age comparison   		33 strains   ages shown
  Inbred
 
endocrine — hormones         radioimmunoassay  
Yuan1
insulin-like growth factor 1 (serum IGF-1) [ng/mL]  
      • 6mo  • 12mo  • 18mo    • age comparison   		33 strains   ages shown
  Inbred



Number of mice tested per strain, for each measurement

  
Changelog There has been one update or correction to the data set since MPD release in Jun 2008  
Reference
Leduc MS, Hageman RS, Meng Q, Verdugo RA, Tsaih SW, Churchill GA, Paigen B, Yuan R. Identification of genetic determinants of IGF-1 levels and longevity among mouse inbred strains. Aging Cell. 2010 Oct;9(5):823-36. doi: 10.1111/j.1474-9726.2010.00612.x.     PubMed 20735370     MGI     FullText


Yuan R, Tsaih SW, Petkova SB, Marin de Evsikova C, Xing S, Marion MA, Bogue MA, Mills KD, Peters LL, Bult CJ, Rosen CJ, Sundberg JP, Harrison DE, Churchill GA, Paigen B. Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels. Aging Cell. 2009 Jun;8(3):277-87. Epub 2009 Apr 9.     PubMed 19627267     MGI     FullText

Related papers
Mice
Strain and animal info
Note
Caution: Very low sample sizes (N < 3) are present. [View table]

Yuan1
downloads


Individual animal data
Table format (.csv)		 Individual animal data in table format, with one row per animal and one column per measurement.
Individual animal data
List format (.csv)		 Individual animal data organized as one row per animal / measurement reading.
Strain means (.csv) Strain means with SD, N, other summary statistics. One row per strain / sex / measurement.
No supplemental data for this project. 

 See also the MPD download center for more general data download options.




 




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