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Project data set: Tordoff3   (2002)

Project Diet preference: Survey of calcium and sodium intake, blood pH and calcium level, and bone and body composition data in 40 inbred strains of mice

Animals were evaluated using Ciba-Corning calcium analyzer and PIXImus II mouse densitometer (DXA).

Study design: baseline survey; 1 cohort.
40 strains tested     female male     Test age: 9-15wks

Investigators Tordoff MG, Bachmanov AA   [Details, papers]
Monell Chemical Senses Center

Protocol View phenotyping protocol and methods

Tordoff3
measurements



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blood — clinical chemistry         metabolic panel  
Tordoff3
blood ionized calcium [mg/dL]        
• Ca   • Ca adj to pH 7.4    • comparison  
40 strains   age 13-15wks
  Inbred
Tordoff3
plasma total calcium   [mg/dL] 40 strains   age 13-15wks
  Inbred
Tordoff3
blood pH   [pH] 40 strains   age 13-15wks
  Inbred
 
body composition         DXA  
Tordoff3
percent fat, head excluded   [%] 40 strains   age 14-18wks
  Inbred
Tordoff3
weight of fat tissue, head excluded   [g] 40 strains   age 14-18wks
  Inbred
Tordoff3
non-fat portion of body mass        
• non-fat weight   • % non-fat 
40 strains   age 14-18wks
  Inbred
Tordoff3
total weight (lean + fat), head excluded   [g] 40 strains   age 14-18wks
  Inbred
 
body weight         scales  
Tordoff3
body weight [g]        
• start   • end   • Δchange    • comparison  
40 strains   age 8-10wks
  Inbred
 
bone — mineral density and content — whole body without head         DXA  
Tordoff3
bone mineral density and content        
• BMD   • BMC 
40 strains   age 14-18wks
  Inbred
 
ingestive preference — salt solutions         gauge  
Tordoff3
preference for CaCl2 (calcium chloride) solutions [%]        
• 7.5mM  • 25  • 75    • comparison  
40 strains   age 9-11wks
  Inbred
Tordoff3
preference for CaLa (calcium lactate) solutions [%]        
• 7.5mM  • 25  • 75    • comparison  
40 strains   age 10-12wks
  Inbred
Tordoff3
preference for NaCl (sodium chloride) solutions [%]        
• 25mM  • 75  • 225    • comparison  
40 strains   age 11-13wks
  Inbred
Tordoff3
preference for NaLa (sodium lactate) solutions [%]        
• 25mM  • 75  • 225    • comparison  
40 strains   age 12-14wks
  Inbred


local experiment parameter  
Tordoff3
age at the start of the 1st test (water)   [d] 40 strains  
  Inbred
Tordoff3
time from tail cut to 1/2 tube of blood
collected (approx 30 µL)
  [s]
40 strains   age 13-15wks
  Inbred
Tordoff3
age of mouse at death   [d] 40 strains  
  Inbred



Number of mice tested per strain, for each measurement

  
Changelog There have been 3 updates or corrections to the data set since MPD release in Nov 2002  
Reference
Reed DR, Bachmanov AA, Tordoff MG. Forty mouse strain survey of body composition. Physiol Behav. 2007 Aug 15;91(5):593-600. Epub 2007 Apr 1.     PubMed 17493645     MGI


Tordoff MG, Bachmanov AA, Reed DR. Forty mouse strain survey of water and sodium intake. Physiol Behav. 2007 Aug 15;91(5):620-31. Epub 2007 Apr 1.     PubMed 17490693     MGI


Tordoff MG, Bachmanov AA, Reed DR. Forty mouse strain survey of voluntary calcium intake, blood calcium, and bone mineral content. Physiol Behav. 2007 Aug 15;91(5):632-43. Epub 2007 Apr 1.     PubMed 17493644     MGI

Related papers
Mice
Strain and animal info
Note
Some measurements were derived by MPD staff,
based on supplied data. [View list]
Note
Some measurements are not eligible for all-MPD pheno vs. pheno
correlations due to data characteristics or semantics [View list]

Tordoff3
downloads


Individual animal data
Table format (.csv)
Individual animal data in table format, with one row per animal and one column per measurement.
Individual animal data
List format (.csv)
Individual animal data organized as one row per animal / measurement reading.
Strain means (.csv) Strain means with SD, N, other summary statistics. One row per strain / sex / measurement.
Supplemental data are available

 See also the MPD download center for more general data download options.





 




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