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Phenotype >
Data set: Schulz1   (2000)

  Lung function survey in 7 inbred strains of mice
 

Study design: baseline survey   1 cohort.
7 strains tested     female male     Test age: 9-18wks
Sample sizes are 14.7 on average.  [details]

  Investigators: Schulz H     [More info... papers, citing, funding]

  • Protocol / methods           • Ontology classifications           • Downloads

Schulz1
phenotype
measurements



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body weight         body weight  
Schulz1
body weight   [g] 7 strains   age 12-14wks
  Inbred
 
respiratory — airway resistance         ventilator  
Schulz1
resistance        
• system resistance  • system resistance adjusted to lung capacity      comparison  
7 strains   age 12-14wks
  Inbred
 
respiratory — lung compliance         ventilator  
Schulz1
compliance [µL/cm]        
• static (system)  • static (lung)  • dynamic      comparison  
7 strains   age 12-14wks
  Inbred
Schulz1
compliance adjusted to lung capacity [1/cm]        
• static  • dynamic      comparison  
7 strains   age 12-14wks
  Inbred
 
respiratory — lung volume         ventilator  
Schulz1
volume [µL]        
• alveolar 
7 strains   age 12-14wks
  Inbred
 
respiratory — mechanics         ventilator  
Schulz1
capacity [µL]        
• inspiratory  • residual  • total  • vital      comparison  
7 strains   age 12-14wks
  Inbred
Schulz1
capacity (adjusted)        
• total adjusted to body weight  • vital adjusted to body weight 
• residual adjusted to body weight 
• residual adjusted to lung capacity      comparison  
7 strains   age 12-14wks
  Inbred
Schulz1
dead space        
• Fowler adjusted to lung capacity  • Fowler adjusted to body weight 
• Fowler dead space volume      comparison  
7 strains   age 12-14wks
  Inbred
 
respiratory — pulmonary gas exchange         ventilator  
Schulz1
gas mixing and diffusing capacity        
• gas mixing  • diffusing capacity 
• diffusing capacity adjusted to alveolar volume      comparison  
7 strains   age 12-14wks
  Inbred


local experiment parameter  
Schulz1
age   [d] 7 strains  
  Inbred




One update or correction was posted since initial release in Nov 2002
 
Reinhard C, Eder G, Fuchs H, Ziesenis A, Heyder J, Schulz H. Inbred strain variation in lung function. Mamm Genome. 2002 Aug;13(8):429-37.     PubMed 12226708     MGI

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