MPD: Data set: Peters1

Peters LL, Cheever EM, Ellis HR, Magnani PA, Svenson KL, Von Smith R, Bogue MA. Large-scale, high-throughput screening for coagulation and hematologic phenotypes in mice. Physiol Genomics. 2002 Dec 3;11(3):185-93. PubMed 12419856

Notes
Animal identifiers were found to not always be consistent when comparing an ADVIA measurement vs. a BCS measurement, animal by animal.

Peters1 downloads
• Download Peters1 project data set animal data, as uploaded
• Download Peters1 animal data matrix with factor-related expansion applied as necessary
• Download Peters1 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to Peters1 measures:

MA:0000059 blood
MP:0000217 abnormal leukocyte cell number
MP:0000226 abnormal mean corpuscular volume
MP:0000717 abnormal lymphocyte cell number
MP:0001586 abnormal erythrocyte cell number
MP:0001588 abnormal hemoglobin
MP:0001589 abnormal mean corpuscular hemoglobin
MP:0002586 abnormal platelet volume
MP:0002596 abnormal hematocrit
MP:0002602 abnormal eosinophil cell number
MP:0005640 abnormal mean corpuscular hemoglobin concentration
MP:0008849 abnormal hemoglobin concentration distribution width
MP:0010066 abnormal red blood cell distribution width
MP:0010213 abnormal circulating fibrinogen level
MP:0011898 abnormal platelet cell number
MP:0011913 abnormal reticulocyte cell number
MP:0012354 abnormal prothrombin time
MP:0012357 abnormal partial thromboplastin time
MP:0012360 abnormal large unstained cell number
MP:0012397 abnormal nucleated erythrocyte cell number
MP:0012440 abnormal neutrophil cell number
MP:0012441 abnormal monocyte cell number
MP:0012442 abnormal basophil cell number
VT:0000217 leukocyte quantity
VT:0000222 neutrophil quantity
VT:0000223 monocyte quantity
VT:0000248 erythrocyte size trait
VT:0000717 lymphocyte quantity
VT:0001586 erythrocyte quantity
VT:0001588 blood hemoglobin amount
VT:0002447 erythrocyte morphology trait
VT:0002551 blood coagulation trait
VT:0002602 eosinophil quantity
VT:0002607 basophil quantity
VT:0003135 reticulocyte quantity
VT:0003179 platelet quantity
VT:0004152 blood iron amount
VT:0010457 platelet size trait
VT:3000003 fibrin formation trait

Investigators	Luanne L Peters The Jackson Laboratory, Bar Harbor, ME Jane E Barker The Jackson Laboratory, Bar Harbor, ME
Participants	Svenson K, Von Smith R
Contact	Luanne L Peters Luanne.Peters@jax.org
Affiliated Center	JAX Heart, Lung, and Blood Center (HLB)
Part of a series:	• Inbred strains (this project) Peters1 • AxB and BxA strains see Peters2 • B6 controls sampled over time see Peters3
Acknowledgements	Funding provided by Program for Genomic Applications (PGA) HL66611. In fulfillment of NIH requirements that all information is made promptly and freely available to the research community, data are deposited in the MPD when complete.
Project type	Phenotype strain survey data set
MPD identifiers	Peters1 MPD:62
Data changelog	7 updates/corrections. Initial release date: 06/2001.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Animals were evaluated using Advia 120 analyzer and Dade Behring BCS automated coagulation analyzer adapted for mice.

Procedures conducted:

• complete blood count		Hematology.
• coagulation test		Fibrinogen.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
Peters1:1	Peters1	complete blood count	(none)	white blood cell count (WBC; per volume x 10³) [n/µL] WBC 6201	inbred w/CC7	43	both	10wks	N=12

Peters1:2	Peters1	complete blood count	(none)	red blood cell count (RBC; per volume x 10⁶) [n/µL] RBC 6202	inbred w/CC7	43	both	10wks	N=12

Peters1:3	Peters1	complete blood count	(none)	measured hemoglobin (HGB) [g/dL] mHGB 6203	inbred w/CC7	43	both	10wks	N=12

Peters1:4	Peters1	complete blood count	(none)	hematocrit (HCT) [%] HCT 6204	inbred w/CC7	43	both	10wks	N=12

Peters1:5	Peters1	complete blood count	(none)	mean RBC corpuscular volume (MCV) [fL] MCV 6205	inbred w/CC7	43	both	10wks	N=12

Peters1:6	Peters1	complete blood count	(none)	mean RBC corpuscular hemoglobin (MCH) [pg] MCH 6206	inbred w/CC7	43	both	10wks	N=12

Peters1:7	Peters1	complete blood count	(none)	mean RBC corpuscular hemoglobin concentration (MCHC) [g/dL] MCHC 6207	inbred w/CC7	43	both	10wks	N=12

Peters1:8	Peters1	complete blood count	(none)	RBC corpuscular hemoglobin concentration mean (CHCM) [g/dL] CHCM 6208	inbred w/CC7	43	both	10wks	N=12

Peters1:9	Peters1	complete blood count	(none)	RBC corpuscular distribution width (RDW) [%] RDW 6209	inbred w/CC7	43	both	10wks	N=12

Peters1:10	Peters1	complete blood count	(none)	hemoglobin concentration distribution width (HDW) [g/dL] HDW 6210	inbred w/CC7	43	both	10wks	N=12

Peters1:11	Peters1	complete blood count	(none)	neutrophil differential (percent of total WBC) [%] NEUT 6211	inbred w/CC7	43	both	10wks	N=12

Peters1:12	Peters1	complete blood count	(none)	lymphocyte differential (percent of total WBC) [%] LYM 6212	inbred w/CC7	43	both	10wks	N=12

Peters1:13	Peters1	complete blood count	(none)	monocyte differential (percent of total WBC) [%] MONO 6213	inbred w/CC7	43	both	10wks	N=11

Peters1:14	Peters1	complete blood count	(none)	eosinophil differential (percent of total WBC) [%] EOS 6214	inbred w/CC7	43	both	10wks	N=11

Peters1:15	Peters1	complete blood count	(none)	large unstained cell differential (percent of total WBC) [%] LUC 6215	inbred w/CC7	43	both	10wks	N=12

Peters1:16	Peters1	complete blood count	(none)	basophil differential (percent of total WBC) [%] BASO 6216	inbred w/CC7	43	both	10wks	N=11

Peters1:17	Peters1	complete blood count	(none)	reticulocyte differential (percent of total RBC) [%] Retic 6217	inbred w/CC7	43	both	10wks	N=12

Peters1:18	Peters1	complete blood count	(none)	calculated hemoglobin (HGB) [g/dL] cHGB 6218	inbred w/CC7	43	both	10wks	N=12

Peters1:19	Peters1	complete blood count	(none)	platelet count (PLT; units per volume x 10³) [n/µL] PLT 6219	inbred w/CC7	43	both	10wks	N=12

Peters1:20	Peters1	complete blood count	(none)	mean platelet volume (MPV) [fL] MPV 6220	inbred w/CC7	43	both	10wks	N=12

Peters1:25	Peters1	coagulation test	(none)	fibrinogen [mg/dL] Fib 6225	inbred w/CC7	43	both	10wks	N=10

Peters1:26	Peters1	coagulation test	(none)	prothrombin time (PT) [s] PT 6226	inbred w/CC7	43	both	10wks	N=11

Peters1:27	Peters1	coagulation test	(none)	partial thromboplastin time (PTT) [s] PTT 6227	inbred w/CC7	43	both	10wks	N=10

Peters1: Hematology and clotting time survey in 43 inbred strains of mice (2001)