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Project data set: Mitchell1   (2010)

Project Evaluating behavioral inhibition using a Go/No-go task in males of 15 inbred mouse strains

Study design: baseline survey; 1 cohort.
15 strains tested     male only     Test age: 5-7wks
Sample sizes are 7.6 on average.  [details]

Investigators Mitchell SH     [Project details, papers, citing]

Protocol View phenotyping protocol and methods

Mitchell1
measurements



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              Ontologies


behavior — impulsivity — attentional set shifting         Go/No-go task  
Mitchell1
response        
• pre-cue rate  • Go hits  • No-go false alarms      comparison  
15 strains   age 5-7wks
  Inbred
Mitchell1
latency to respond [s]        
• Go cue  • No-go cue      comparison  
15 strains   age 5-7wks
  Inbred
Mitchell1
measures of efficiency and discrimination [ratio]        
• target specificity  • efficiency  • discrimination      comparison  
15 strains   age 5-7wks
  Inbred
 
behavior — locomotor activity         monitoring system  
Mitchell1
ambulatory activity [cm]        
• day2 activity  • habituation 
15 strains   age 5-7wks
  Inbred


local experiment parameter  
Mitchell1
daily sucrose intake, two bottle choice test   [g/kg] 15 strains   age 5-7wks
  Inbred
Mitchell1
daily water intake, two bottle choice test   [mL/kg] 15 strains   age 5-7wks
  Inbred


  
Reference
Gubner NR, Wilhelm CJ, Phillips TJ, Mitchell SH. Strain differences in behavioral inhibition in a Go/No-go task demonstrated using 15 inbred mouse strains. Alcohol Clin Exp Res. 2010 Aug;34(8):1353-62. Epub 2010 May 14.     PubMed 20491731     MGI

See also these related papers


Mice

Strain and animal info

Citing

Cite this MPD data set

Changelog

No updates or corrections have been posted since MPD release in Aug 2011  

Note

MPD curation note: Responses to light or sound cues are highly dependant on visual or hearing ability. This information is critical to understanding and utilizing the data from this project. Several strains tested are visually impaired by 3 wks of age while others are hearing impaired (variable onset, depending on genetic background).
  • Vision: the following strains are homozygous for the retinal degeneration mutation, Pde6brd1 (phosphodiesterase 6B): C3H/HeJ, CBA/J, PL/J, SJL/J, SWR/J.
  • Hearing: the following strains are homozygous for the age-related hearing loss mutation, Cdh23ahl (cadherin 23, otocadherin): 129P3/J, C57L/J, C57BL/6J, C58/J, DBA/1J, DBA/2J.

Mitchell1
downloads


Individual animal data
Table format (.csv)
All individual animal data, table format, one row per animal and one column per measurement.
Individual animal data
List format (.csv)
All numeric animal data values, one row per animal per measurement.
Strain means (.csv) Strain means with SD, N, other summary statistics. One row per strain / sex / measurement.
No supplemental data for this project. 

 See also MPD's general data download page for other options.





 




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