at The Jackson Laboratory

      Home       About             Help      

Phenotype >
Project data set: Klaassen1   (2001)


DBA warning: phenods entry not found
Project Cadmium toxicity in the testes, liver, and trigeminal ganglia in males of 8 inbred strains of mice

Study design: control vs. an intervention; 2 cohorts.
8 strains tested     male only     Test age: 8wks

Investigators Klaassen CD   [Details, papers]   [Citing]

Protocol View phenotyping protocol and methods

Klaassen1
measurements



Apply tools
          Ontologies


liver — pathology — hepatotoxicity         histopathology  
Klaassen1
Cd-induced toxicity to liver   [designation]   cadmium 9 strains   age 8wks
  Inbred
 
nervous system — morphology — neurotoxicity         histopathology  
Klaassen1
Cd-induced toxicity to trigeminal ganglia   [designation]   cadmium 9 strains   age 8wks
  Inbred
 
reproduction — morphology — male — testicular toxicity         histopathology  
Klaassen1
Cd-induced toxicity to testis   [designation]   cadmium 9 strains   age 8wks
  Inbred



Number of mice tested per strain, for each measurement

  
Reference
Habeebu SS, Liu Y, Park JD, Klaassen CD. Strain differences in the toxicity of cadmium to trigeminal ganglia in mice. Toxicol Appl Pharmacol. 2001 Dec 15;177(3):200-7.     PubMed 11749119     MGI

Related papers       Cite the MPD data set

MiceStrain and animal info
Changelog No updates or corrections have been posted since MPD release in Mar 2004  
Note A tissue or organ is resistant to Cd toxicity if there is no biochemical and/or morphological evidence of toxicity despite increasing doses of Cd to the lethal range.
ValueDescription
Rresistant
Ssensitive
HShighly sensitive
1degeneration only
2degeneration, hemorrhage
3degeneration, necrosis
4degeneration, hemorrhage, necrosis
Note
Please note: Low sample sizes (N < 5) are present. [View table]

Klaassen1
downloads


Individual animal dataNot accessioned
Strain means (.csv) Strain means with SD, N, other summary statistics. One row per strain / sex / measurement.
No supplemental data for this project. 

 See also MPD's general data download page for other options.





 




Contact us
About MPD
Also at JAX
  Units
Changelog
Downloads
  Citing
Funding
Terms of Use