|Project data set: Graubert1 (2006)|
Drug study: ENU-induced tumorigenesis in 20 inbred strains of mice
An investigation of secondary malignancies and whether certain susceptibilities are genetically predetermined.
Animals were evaluated for baseline hematology. Some animals were treated with
and then evaluated for tumor burden in the blood, lungs, and gastrointestinal system.
There were two cohorts: 1) controls;
2) treated with 100 mg/kg body weight ENU i.p.
Study design: control vs. an intervention;
Graubert TA, Watters JW, McLeod HL
View phenotyping protocol and methods
Number of mice tested per strain, for each measurement
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Fenske TS, McMahon C, Edwin D, Jarvis JC, Cheverud JM, Minn M, Mathews V, Bogue MA, Province MA, McLeod HL, Graubert TA. Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice.
Cancer Res. 2006 May 15;66(10):5029-38.
Cite the MPD data set
|Mice||Strain and animal info|
2 updates or corrections
was posted since MPD release
Caution: Very low sample sizes (N < 3) are present.
Some measurements are not eligible for all-MPD pheno vs. pheno
correlations due to data characteristics or semantics
See also the MPD download center for more general data download options.