Phenotype >
| Project data set: Crabbe3 (2003) |
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| | Project |
Drug study: Evaluation of ethanol intoxication using the rotorod in 22 inbred strains of mice
Animals were evaluated on an accelerating
and fixed speed rotarod following ethanol administration. This project has a complex study design
involving multiple cohorts, as described in the protocol workflow table.
Study design:
baseline and intervention in various doses;
9 cohorts.
22 strains tested
Test age:
9-17wks
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| Investigators |
Crabbe JC, Wahlsten D
[Details, papers]
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| Protocol |
View phenotyping protocol and methods
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Crabbe3 measurements
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behavior — balance and coordination
rotarod
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fixed speed 3 rpm rotarod (latency to fall)
[s]
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ethanol
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ethanol i.p. g/kg:
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Inbred
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fixed speed 6 rpm rotarod (latency to fall)
[s]
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ethanol
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ethanol i.p. g/kg:
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Inbred
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fixed speed 10 rpm rotarod (latency to fall)
[s]
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ethanol
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ethanol i.p. g/kg:
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Inbred
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accelerating rotarod (latency to fall) - acquisition trials 20 rpm/min
[s]
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Inbred
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accelerating rotarod (latency to fall) - test day 1 20 rpm/min (ARR1)
[s]
| baseline and
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ethanol
various i.p.
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Inbred
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accelerating rotarod (latency to fall) - test day 2 30 rpm/min (ARR1)
[s]
| baseline and
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ethanol
various i.p.
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Inbred
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accelerating rotarod (latency to fall) - acquisition trials 20 rpm/min (ARR2)
[s]
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Inbred
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accelerating rotarod (latency to fall) - test 20 rpm/min (ARR2)
[s]
| baseline and
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ethanol
2g/kg i.p.
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Inbred
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local experiment parameter
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Inbred
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Number of mice tested per strain, for each measurement
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| Changelog |
There have been no updates or corrections
to the data set since MPD release
in
Feb 2010
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| Reference |
Rustay NR, Wahlsten D, Crabbe JC. Assessment of genetic susceptibility to ethanol intoxication in mice.
Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2917-22. Epub 2003 Feb 12.
PubMed 12584362
MGI
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| Mice |
Strain and animal info
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| Note |
Caution: Very low sample sizes (N < 3) are present.
[View table]
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| Note |
Some measurements are a mixture of + and – values. [View list]
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Crabbe3
downloads
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See also the MPD download center for more general data download options.
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