Cowell1: Host response to Staphylococcus aureus infection in females of 13 inbred strains of mice (2012)

Johnson NV, Ahn SH, Deshmukh H, Levin MK, Nelson CL, Scott WK, Allen A, Fowler VG Jr, Cowell LG. Haplotype Association Mapping Identifies a Candidate Gene Region in Mice Infected With Staphylococcus aureus. G3 (Bethesda). 2012 Jun;2(6):693-700. Epub 2012 Jun 1.   PubMed 22690378     FullText


         
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Investigators Lindsay G Cowell       University of Texas - Southwestern,  Dallas, TX
Vance G Fowler       Duke University Medical Center,  Durham, NC
Participants Johnson NV, Ahn SH, Deshmukh H, Levin MK, Nelson CL, Scott WK, Allen A
ContactLindsay G Cowell     Lindsay.Cowell@UTSouthwestern.edu     Lab web site
AcknowledgementsFunding provided by NIH AI068804, AI077706; Burroughs Wellcome Fund
Project type Phenotype strain survey data set
MPD identifiersCowell1     MPD:490
Data changelog No updates/corrections.       Initial release date: 10/2013.
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Procedures conducted:
• health assessment  Survival rate, Staphylococcus aureus.
• hormone quantification  Interleukin 6 levels (serum) after infection with Staphylococcus aureus. Kidney and peritoneal fluid.
• in vitro assay  Bacterial load after infection with Staphylococcus aureus. Kidney and peritoneal fluid. In vitro assay.

Mice: inbred   13 strains   ♀   age 8wks   3 experimental groups