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Project data set: Berndt1   (2010)

Project Methacholine-induced changes in airway resistance in 37 inbred strains of mice

Study design: baseline and intervention in various doses; 1 cohort.
37 strains tested     female male     Test age: 9-12wks

Investigators Berndt A, Leme AS, Paigen B, Shapiro SD   [Details, papers]

Protocol View phenotyping protocol and methods

Berndt1
measurements



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          Ontologies


respiratory — airway resistance         ventilator  
Berndt1
resistance [cm/mL/s]  
      • untreated 
36 strains   age 9-12wks
  Inbred
Berndt1
resistance [cm/mL/s]     baseline and  methacholine
      • baseline    MCh challenge (mg/mL): • 1   • 3   • 10   • 30    • comparison  
36 strains   age 9-12wks
  Inbred
Berndt1
resistance (percent of baseline) [%]   methacholine
      MCh challenge (mg/mL): • 1   • 3   • 10   • 30    • comparison  
36 strains   age 9-12wks
  Inbred



Number of mice tested per strain, for each measurement

  
Changelog There has been one update or correction to the data set since MPD release in Jul 2010  
Reference
Leme AS, Berndt A, Williams LK, Tsaih SW, Szatkiewicz JP, Verdugo R, Paigen B, Shapiro SD. A survey of airway responsiveness in 36 inbred mouse strains facilitates gene mapping studies and identification of quantitative trait loci. Mol Genet Genomics. 2010 Apr;283(4):317-26. Epub 2010 Feb 9.     PubMed 20143096     MGI     FullText

Related papers
Mice
Strain and animal info
Note
Caution: Very low sample sizes (N < 3) are present. [View table]
Note
Some measurements were derived by MPD staff,
based on supplied data. [View list]

Berndt1
downloads


Individual animal data
Table format (.csv)
Individual animal data in table format, with one row per animal and one column per measurement.
Individual animal data
List format (.csv)
Individual animal data organized as one row per animal / measurement reading.
Strain means (.csv) Strain means with SD, N, other summary statistics. One row per strain / sex / measurement.
No supplemental data for this project. 

 See also the MPD download center for more general data download options.





 




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